Laurent Chiarelli

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Giovanna ValentiniAssociated Professor, Department of Biology and Biotechnology, University of PaviaAdresse e-mail validée de unipv.it
Maria Rosalia PascaDept. Biology and Biotechnology "L. Spallanzani", UNIVERSITY OF PAVIAAdresse e-mail validée de unipv.it
Riccardi GiovannaPROFESSOR OF MICROBIOLOGYAdresse e-mail validée de unipv.it
Giovanni StelitanoUniversità di PaviaAdresse e-mail validée de unipv.it
Degiacomi GiuliaUniversità di PaviaAdresse e-mail validée de unipv.it
Andrea MatteviProfessor of Molecular Biology, Department of Biology and Biotechnology, University of Pavia.Adresse e-mail validée de unipv.it
Giorgia MoriAustralian BiocommonsAdresse e-mail validée de biocommons.org.au
Claudia ScottiUniversity of Pavia - Department of Molecular MedicineAdresse e-mail validée de unipv.it
Scoffone Viola CamillaDepartment of Biology and Biotechnology, University of PaviaAdresse e-mail validée de unipv.it
Tiziano TuccinardiAssociate Professor, University of PisaAdresse e-mail validée de unipi.it
JOSE' CAMILLA SAMMARTINOResearcher, Università degli Studi di Pavia Dipartimento di Scienze Clinico-Chirurgiche DiagnosticheAdresse e-mail validée de iusspavia.it
Katarína MikušováProfessor of Biochemistry, Comenius University in Bratislava, Faculty of Natural SciencesAdresse e-mail validée de uniba.sk
Alberto AzzalinTecnico di laboratorio, Dip. di Biologia a Biotecnologie "L. Spallanzani" - Università di PaviaAdresse e-mail validée de unipv.it
Marco BellinzoniInstitut PasteurAdresse e-mail validée de pasteur.fr
Donata CappellettiPhDAdresse e-mail validée de unipv.it
Stewart ColeInstitut PasteurAdresse e-mail validée de pasteur.fr
Gabriele TrespidiPost Doc, Università degli studi di PaviaAdresse e-mail validée de unipv.it
Federico FornerisArmenise-Harvard Laboratory, Department of Biology and Biotechnology, University of PaviaAdresse e-mail validée de unipv.it
Jana KordulakovaAdresse e-mail validée de fns.uniba.sk
De Rossi EddaAdresse e-mail validée de unipv.it

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Laurent Chiarelli

Department of Biology and Biotechnology, University of Pavia

Adresse e-mail validée de unipv.it - Page d'accueil

Biochemistry Medicinal Chemistry Infectious Diseases


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
ThermoFAD, a Thermofluor^®‐adapted flavin ad hoc detection system for protein folding and ligand binding F Forneris, R Orru, D Bonivento, LR Chiarelli, A Mattevi The FEBS journal 276 (10), 2833-2840, 2009	241	2009
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ... Science translational medicine 4 (150), 150ra121-150ra121, 2012	222	2012
The allosteric regulation of pyruvate kinase: a site-directed mutagenesis study G Valentini, L Chiarelli, R Fortin, ML Speranza, A Galizzi, A Mattevi Journal of Biological Chemistry 275 (24), 18145-18152, 2000	222	2000
Pyruvate kinase deficiency: the genotype-phenotype association A Zanella, E Fermo, P Bianchi, LR Chiarelli, G Valentini Blood reviews 21 (4), 217-231, 2007	211	2007
Burkholderia cenocepacia Infections in Cystic Fibrosis Patients: Drug Resistance and Therapeutic Approaches VC Scoffone, LR Chiarelli, G Trespidi, M Mentasti, G Riccardi, S Buroni Frontiers in microbiology 8, 1592, 2017	187	2017
Structure and function of human erythrocyte pyruvate kinase: molecular basis of nonspherocytic hemolytic anemia G Valentini, LR Chiarelli, R Fortin, M Dolzan, A Galizzi, DJ Abraham, ... Journal of Biological Chemistry 277 (26), 23807-23814, 2002	175	2002
Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients G Degiacomi, JC Sammartino, LR Chiarelli, O Riabova, V Makarov, ... International journal of molecular sciences 20 (23), 5868, 2019	146	2019
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1 J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ... ACS chemical biology 10 (3), 705-714, 2015	141	2015
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis G Riccardi, MR Pasca, LR Chiarelli, G Manina, A Mattevi, C Binda Applied microbiology and biotechnology 97, 8841-8848, 2013	132	2013
Expanding targets for a metabolic therapy of cancer: L-asparaginase D Covini, S Tardito, O Bussolati, L R Chiarelli, M V Pasquetto, R Digilio, ... Recent patents on anti-cancer drug discovery 7 (1), 4-13, 2012	132	2012
Helicobacter pyloril-asparaginase: a promising chemotherapeutic agent D Cappelletti, LR Chiarelli, MV Pasquetto, S Stivala, G Valentini, C Scotti Biochemical and biophysical research communications 377 (4), 1222-1226, 2008	120	2008
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ... Molecular microbiology 77 (5), 1172-1185, 2010	104	2010
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ... Journal of medicinal chemistry 57 (12), 5419-5434, 2014	99	2014
Mechanochemical synthesis and biological evaluation of novel isoniazid derivatives with potent antitubercular activity PFM Oliveira, B Guidetti, A Chamayou, C André-Barrès, J Madacki, ... Molecules 22 (9), 1457, 2017	91	2017
Structure of a lectin with antitumoral properties in king bolete (Boletus edulis) mushrooms M Bovi, ME Carrizo, S Capaldi, M Perduca, LR Chiarelli, M Galliano, ... Glycobiology 21 (8), 1000-1009, 2011	89	2011
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ... ACS chemical biology 8 (8), 1677-1682, 2013	84	2013
BEL β-trefoil: A novel lectin with antineoplastic properties in king bolete (Boletus edulis) mushrooms M Bovi, L Cenci, M Perduca, S Capaldi, ME Carrizo, L Civiero, ... Glycobiology 23 (5), 578-592, 2013	83	2013
Thiophenecarboxamide derivatives activated by EthA kill Mycobacterium tuberculosis by inhibiting the CTP synthetase PyrG G Mori, LR Chiarelli, M Esposito, V Makarov, M Bellinzoni, RC Hartkoorn, ... Chemistry & biology 22 (7), 917-927, 2015	81	2015
Molecular insights on pathogenic effects of mutations causing phosphoglycerate kinase deficiency LR Chiarelli, SM Morera, P Bianchi, E Fermo, A Zanella, A Galizzi, ... PLOS one 7 (2), e32065, 2012	80	2012
Quorum sensing as antivirulence target in cystic fibrosis pathogens VC Scoffone, G Trespidi, LR Chiarelli, G Barbieri, S Buroni International journal of molecular sciences 20 (8), 1838, 2019	79	2019

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