Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor A Brunet, A Bonni, MJ Zigmond, MZ Lin, P Juo, LS Hu, MJ Anderson, ... cell 96 (6), 857-868, 1999 | 8208 | 1999 |
Cellular survival: a play in three Akts SR Datta, A Brunet, ME Greenberg Genes & development 13 (22), 2905-2927, 1999 | 5531 | 1999 |
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase A Brunet, LB Sweeney, JF Sturgill, KF Chua, PL Greer, Y Lin, H Tran, ... science 303 (5666), 2011-2015, 2004 | 3867 | 2004 |
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and-independent mechanisms A Bonni, A Brunet, AE West, SR Datta, MA Takasu, ME Greenberg Science 286 (5443), 1358-1362, 1999 | 2549 | 1999 |
Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 2375 | 2014 |
FOXO transcription factors at the interface between longevity and tumor suppression EL Greer, A Brunet Oncogene 24 (50), 7410-7425, 2005 | 1641 | 2005 |
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway JN Lavoie, G L'Allemain, A Brunet, R Müller, J Pouysségur Journal of Biological Chemistry 271 (34), 20608-20616, 1996 | 1637 | 1996 |
Transcription-dependent and-independent control of neuronal survival by the PI3K–Akt signaling pathway A Brunet, SR Datta, ME Greenberg Current opinion in neurobiology 11 (3), 297-305, 2001 | 1510 | 2001 |
The foxo code DR Calnan, A Brunet Oncogene 27 (16), 2276-2288, 2008 | 1429 | 2008 |
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a) A Brunet, J Park, H Tran, LS Hu, BA Hemmings, ME Greenberg Molecular and cellular biology, 2001 | 1089 | 2001 |
DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein H Tran, A Brunet, JM Grenier, SR Datta, AJ Fornace Jr, PS DiStefano, ... Science 296 (5567), 530-534, 2002 | 1062 | 2002 |
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor EL Greer, PR Oskoui, MR Banko, JM Maniar, MP Gygi, SP Gygi, A Brunet Journal of Biological Chemistry 282 (41), 30107-30119, 2007 | 975 | 2007 |
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans EL Greer, D Dowlatshahi, MR Banko, J Villen, K Hoang, D Blanchard, ... Current biology 17 (19), 1646-1656, 2007 | 941 | 2007 |
AMPK: an energy-sensing pathway with multiple inputs and outputs DG Hardie, BE Schaffer, A Brunet Trends in cell biology 26 (3), 190-201, 2016 | 892 | 2016 |
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts P Lenormand, C Sardet, G Pages, G L'Allemain, A Brunet, J Pouysségur The Journal of cell biology 122 (5), 1079-1088, 1993 | 863 | 1993 |
Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry A Brunet, D Roux, P Lenormand, S Dowd, S Keyse, J Pouysségur The EMBO journal, 1999 | 768 | 1999 |
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport A Brunet, F Kanai, J Stehn, J Xu, D Sarbassova, JV Frangioni, SN Dalal, ... The Journal of cell biology 156 (5), 817-828, 2002 | 722 | 2002 |
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans EL Greer, TJ Maures, D Ucar, AG Hauswirth, E Mancini, JP Lim, ... Nature 479 (7373), 365-371, 2011 | 716 | 2011 |
FoxO transcription factors in the maintenance of cellular homeostasis during aging DAM Salih, A Brunet Current opinion in cell biology 20 (2), 126-136, 2008 | 693 | 2008 |
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons OL Wapinski, T Vierbuchen, K Qu, QY Lee, S Chanda, DR Fuentes, ... Cell 155 (3), 621-635, 2013 | 669 | 2013 |