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Elena Lopez Knowles
Elena Lopez Knowles
Adresse e-mail validée de icr.ac.uk
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Comparison of PAM50 Risk of Recurrence Score With Oncotype DX and IHC4 for Predicting Risk of Distant Recurrence After Endocrine Therapy
M Dowsett, I Sestak, E Lopez-Knowles, K Sidhu, AK Dunbier, JW Cowens, ...
Journal of Clinical Oncology 31 (22), 2783-2790, 2013
7742013
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
G Schiavon, S Hrebien, I Garcia-Murillas, RJ Cutts, A Pearson, ...
Science translational medicine 7 (313), 313ra182-313ra182, 2015
6092015
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene …
DC Sgroi, I Sestak, J Cuzick, Y Zhang, CA Schnabel, B Schroeder, ...
The lancet oncology 14 (11), 1067-1076, 2013
4592013
Prospective Study of FGFR3 Mutations As a Prognostic Factor in Nonmuscle Invasive Urothelial Bladder Carcinomas
S Hernández, E López-Knowles, J Lloreta, M Kogevinas, A Amorós, ...
Journal of Clinical Oncology 24 (22), 3664-3671, 2006
4152006
PI3K pathway activation in breast cancer is associated with the basal‐like phenotype and cancer‐specific mortality
E López‐Knowles, SA O'Toole, CM McNeil, EKA Millar, MR Qiu, P Crea, ...
International journal of cancer 126 (5), 1121-1131, 2010
4092010
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
CG Fedele, LM Ooms, M Ho, J Vieusseux, SA O'Toole, EK Millar, ...
Proceedings of the National Academy of Sciences 107 (51), 22231-22236, 2010
3402010
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy
C Balbás-Martínez, A Sagrera, E Carrillo-de-Santa-Pau, J Earl, ...
Nature genetics 45 (12), 1464-1469, 2013
3352013
PIK3CA Mutations Are an Early Genetic Alteration Associated with FGFR3 Mutations in Superficial Papillary Bladder Tumors
E López-Knowles, S Hernández, N Malats, M Kogevinas, J Lloreta, ...
Cancer research 66 (15), 7401-7404, 2006
2912006
Prediction of late distant recurrence after 5 years of endocrine treatment: a combined analysis of patients from the Austrian breast and colorectal cancer study group 8 and …
I Sestak, J Cuzick, M Dowsett, E Lopez-Knowles, M Filipits, P Dubsky, ...
Journal of clinical oncology 33 (8), 916-922, 2015
2792015
Factors predicting late recurrence for estrogen receptor–positive breast cancer
I Sestak, M Dowsett, L Zabaglo, E Lopez-Knowles, S Ferree, JW Cowens, ...
Journal of the National Cancer Institute 105 (19), 1504-1511, 2013
2612013
Oncogenic PIK3CA mutations occur in epidermal nevi and seborrheic keratoses with a characteristic mutation pattern
C Hafner, E López-Knowles, NM Luis, A Toll, E Baselga, ...
Proceedings of the National Academy of Sciences 104 (33), 13450-13454, 2007
2542007
Cytoplasmic localization of β-catenin is a marker of poor outcome in breast cancer patients
E López-Knowles, SJ Zardawi, CM McNeil, EKA Millar, P Crea, ...
Cancer epidemiology, biomarkers & prevention 19 (1), 301-309, 2010
2192010
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ...
Nature genetics 48 (4), 374-386, 2016
1642016
FGFR3 and Tp53 Mutations in T1G3 Transitional Bladder Carcinomas: Independent Distribution and Lack of Association with Prognosis
S Hernández, E López-Knowles, J Lloreta, M Kogevinas, R Jaramillo, ...
Clinical Cancer Research 11 (15), 5444-5450, 2005
1592005
Identifying clinically relevant prognostic subgroups of postmenopausal women with node-positive hormone receptor-positive early-stage breast cancer treated with endocrine …
M Gnant, I Sestak, M Filipits, M Dowsett, M Balic, E Lopez-Knowles, ...
Annals of Oncology 26 (8), 1685-1691, 2015
1462015
Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data
D Zardavas, L Te Marvelde, RL Milne, D Fumagalli, G Fountzilas, ...
Journal of Clinical Oncology 36 (10), 981-990, 2018
1332018
Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance
A Pearson, P Proszek, J Pascual, C Fribbens, MK Shamsher, B Kingston, ...
Clinical Cancer Research 26 (3), 608-622, 2020
1242020
Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment
SC Drury, S Detre, A Leary, J Salter, J Reis-Filho, V Barbashina, ...
Endocrine Related Cancer 18 (5), 565, 2011
1092011
β-Catenin signaling is a critical event in ErbB2-mediated mammary tumor progression
B Schade, R Lesurf, V Sanguin-Gendreau, T Bui, G Deblois, SA O'Toole, ...
Cancer research 73 (14), 4474-4487, 2013
882013
High Notch1 protein expression is an early event in breast cancer development and is associated with the HER‐2 molecular subtype
SJ Zardawi, I Zardawi, CM McNeil, EKA Millar, D McLeod, AL Morey, ...
Histopathology 56 (3), 286-296, 2010
872010
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