De novo mutations in histone-modifying genes in congenital heart disease S Zaidi, M Choi, H Wakimoto, L Ma, J Jiang, JD Overton, ... Nature 498 (7453), 220-223, 2013 | 1003 | 2013 |
Two populations of node monocilia initiate left-right asymmetry in the mouse J McGrath, S Somlo, S Makova, X Tian, M Brueckner Cell 114 (1), 61-73, 2003 | 935 | 2003 |
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies J Homsy, S Zaidi, Y Shen, JS Ware, KE Samocha, KJ Karczewski, ... Science 350 (6265), 1262-1266, 2015 | 836 | 2015 |
Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands SC Jin, J Homsy, S Zaidi, Q Lu, S Morton, SR DePalma, X Zeng, H Qi, ... Nature genetics 49 (11), 1593-1601, 2017 | 822 | 2017 |
Mutation of an axonemal dynein affects left–right asymmetry in inversus viscerum mice DM Supp, DP Witte, SS Potter, M Brueckner Nature 389 (6654), 963-966, 1997 | 627 | 1997 |
Genetic basis for congenital heart disease: revisited: a scientific statement from the American Heart Association ME Pierpont, M Brueckner, WK Chung, V Garg, RV Lacro, AL McGuire, ... Circulation 138 (21), e653-e711, 2018 | 582 | 2018 |
Genetics and genomics of congenital heart disease S Zaidi, M Brueckner Circulation research 120 (6), 923-940, 2017 | 510 | 2017 |
Conserved function for embryonic nodal cilia JJ Essner, KJ Vogan, MK Wagner, CJ Tabin, HJ Yost, M Brueckner Nature 418 (6893), 37-38, 2002 | 460 | 2002 |
Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data JT Glessner, AG Bick, K Ito, JG Homsy, L Rodriguez-Murillo, M Fromer, ... Circulation research 115 (10), 884-896, 2014 | 286 | 2014 |
Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning KA Fakhro, M Choi, SM Ware, JW Belmont, JA Towbin, RP Lifton, ... Proceedings of the National Academy of Sciences 108 (7), 2915-2920, 2011 | 284 | 2011 |
Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries DM Supp, M Brueckner, MR Kuehn, DP Witte, LA Lowe, J McGrath, ... Development 126 (23), 5495-5504, 1999 | 279 | 1999 |
GATA4 haploinsufficiency in patients with interstitial deletion of chromosome region 8p23.1 and congenital heart disease T Pehlivan, BR Pober, M Brueckner, S Garrett, R Slaugh, R Van Rheeden, ... American journal of medical genetics 83 (3), 201-206, 1999 | 256 | 1999 |
Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused AF Cooper, KP Yu, M Brueckner, LL Brailey, L Johnson, JM McGrath, ... Oxford University Press for The Company of Biologists Limited 132 (19), 4407 …, 2005 | 239 | 2005 |
Linkage mapping of a mouse gene, iv, that controls left-right asymmetry of the heart and viscera. M Brueckner, P D'Eustachio, AL Horwich Proceedings of the National Academy of Sciences 86 (13), 5035-5038, 1989 | 214 | 1989 |
Aberrant Wnt/β-catenin signaling can induce chromosomal instability in colon cancer MV Hadjihannas, M Brückner, B Jerchow, W Birchmeier, W Dietmaier, ... Proceedings of the National Academy of Sciences 103 (28), 10747-10752, 2006 | 203 | 2006 |
TBX5 genetic testing validates strict clinical criteria for Holt-Oram syndrome DA McDermott, MC Bressan, JIE He, JS Lee, S Aftimos, M Brueckner, ... Pediatric research 58 (5), 981-986, 2005 | 192 | 2005 |
The congenital heart disease genetic network study: rationale, design, and early results Pediatric Cardiac Genomics Consortium, Writing Committee:, B Gelb, ... Circulation research 112 (4), 698-706, 2013 | 185 | 2013 |
The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality MT Boskovski, S Yuan, NB Pedersen, CK Goth, S Makova, H Clausen, ... Nature 504 (7480), 456-459, 2013 | 183 | 2013 |
Intraciliary calcium oscillations initiate vertebrate left-right asymmetry S Yuan, L Zhao, M Brueckner, Z Sun Current biology 25 (5), 556-567, 2015 | 182 | 2015 |
The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle EE Davis, M Brueckner, N Katsanis Developmental cell 11 (1), 9-19, 2006 | 172 | 2006 |