Phosphodiesterase 5/protein kinase G signal governs stemness of prostate cancer stem cells through Hippo pathway N Liu, L Mei, X Fan, C Tang, X Ji, X Hu, W Shi, Y Qian, M Hussain, J Wu, ... Cancer Letters 378 (1), 38-50, 2016 | 83 | 2016 |
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation W Shi, X Sheng, KM Dorr, JE Hutton, JI Emerson, HA Davies, TD Andrade, ... Developmental cell 56 (21), 3019-3034. e7, 2021 | 68 | 2021 |
Cdc42 is essential for both articular cartilage degeneration and subchondral bone deterioration in experimental osteoarthritis X Hu, X Ji, M Yang, S Fan, J Wang, M Lu, W Shi, L Mei, C Xu, X Fan, ... Journal of Bone and Mineral Research 33 (5), 945-958, 2018 | 44 | 2018 |
Inhibition of phosphodiesterase 5 reduces bone mass by suppression of canonical Wnt signaling Y Gong, CY Xu, JR Wang, XH Hu, D Hong, X Ji, W Shi, HX Chen, ... Cell Death & Disease 5 (11), e1544-e1544, 2014 | 33 | 2014 |
RhoA/Rock activation represents a new mechanism for inactivating Wnt/β-catenin signaling in the aging-associated bone loss W Shi, C Xu, Y Gong, J Wang, Q Ren, Z Yan, L Mei, C Tang, X Ji, X Hu, ... Cell Regeneration 10, 1-19, 2021 | 32 | 2021 |
CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart ZL Robbe, W Shi, LK Wasson, AP Scialdone, CM Wilczewski, X Sheng, ... Genes & Development 36 (7-8), 468-482, 2022 | 30 | 2022 |
The emerging roles of nitric oxide in ferroptosis and pyroptosis of tumor cells Q He, M Qu, C Xu, W Shi, M Hussain, G Jin, H Zhu, LH Zeng, X Wu Life sciences 290, 120257, 2022 | 28 | 2022 |
High expression of Sonic hedgehog in allergic airway epithelia contributes to goblet cell metaplasia C Xu, C Zou, M Hussain, W Shi, Y Shao, Z Jiang, X Wu, M Lu, J Wu, Q Xie, ... Mucosal immunology 11 (5), 1306-1315, 2018 | 28 | 2018 |
Ginkgolide B functions as a determinant constituent of Ginkgolides in alleviating lipopolysaccharide-induced lung injury F Wu, W Shi, G Zhou, H Yao, C Xu, W Xiao, J Wu, X Wu Biomedicine & pharmacotherapy 81, 71-78, 2016 | 26 | 2016 |
SUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions L Mei, L Yuan, W Shi, S Fan, C Tang, X Fan, W Yang, Y Qian, M Hussain, ... Cancer Letters 386, 1-11, 2017 | 24 | 2017 |
Signaling cascades governing Cdc42-mediated chondrogenic differentiation and mensenchymal condensation J Wang, C Wang, C Xu, X Wu, D Hong, W Shi, Y Gong, H Chen, F Long, ... Genetics 202 (3), 1055-1069, 2016 | 23 | 2016 |
Endothelial Rac1 is essential for hematogenous metastasis to the lung H Yao, W Shi, J Wu, C Xu, J Wang, Y Shao, X Wu, Z Zhang Oncotarget 6 (19), 17501, 2015 | 19 | 2015 |
Vitamin C deficiency exacerbates diabetic glomerular injury through activation of transforming growth factor-β signaling X Ji, X Hu, C Zou, H Ruan, X Fan, C Tang, W Shi, L Mei, H Zhu, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (9), 2186-2195, 2017 | 16 | 2017 |
Missense mutation in human CHD4 causes ventricular noncompaction by repressing ADAMTS1 W Shi, AP Scialdone, JI Emerson, L Mei, LK Wasson, HA Davies, ... Circulation Research 133 (1), 48-67, 2023 | 8 | 2023 |
CHD4 and SMYD1 repress common transcriptional programs in the developing heart W Shi, LK Wasson, KM Dorr, ZL Robbe, CM Wilczewski, AJ Hepperla, ... Development 151 (8), 2024 | 6 | 2024 |
Sex Differences in Mouse Cardiac Electrophysiology Revealed by Simultaneous Imaging of Excitation-Contraction Coupling JI Emerson, P Ariel, W Shi, FL Conlon Journal of Cardiovascular Development and Disease 10 (12), 479, 2023 | 5 | 2023 |
Hippo signaling activates hedgehog signaling by Taz-driven Gli3 processing C Tang, J Wang, M Yao, X Ji, W Shi, C Xu, LH Zeng, X Wu Cell Regeneration 12 (1), 3, 2023 | 4 | 2023 |
SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling L Mei, M Qv, H Bao, Q He, Y Xu, Q Zhang, W Shi, Q Ren, Z Yan, C Xu, ... Oncogene 40 (35), 5357-5366, 2021 | 4 | 2021 |
T851I mutation of human large tumor suppressor 1 disrupts its kinase activity and tumor-suppressor functions Q Zhang, X Du, Q He, W Shi, L Mei, M Qv, D Tan, J Wu, LH Zeng, X Wu Life Sciences 264, 118655, 2021 | 3 | 2021 |
X-Chromosome–Linked miRNAs Regulate Sex Differences in Cardiac Physiology JI Emerson, W Shi, J Paredes-Larios, WG Walker, JE Hutton, IM Cristea, ... Circulation Research, 2025 | 1 | 2025 |