NCLX is an essential component of mitochondrial Na+/Ca2+ exchange R Palty, WF Silverman, M Hershfinkel, T Caporale, SL Sensi, J Parnis, ... Proceedings of the National Academy of Sciences 107 (1), 436-441, 2010 | 925 | 2010 |
Zinc in the physiology and pathology of the CNS SL Sensi, P Paoletti, AI Bush, I Sekler Nature reviews neuroscience 10 (11), 780-791, 2009 | 864 | 2009 |
Role of GPR40 in fatty acid action on the β cell line INS-1E H Shapiro, S Shachar, I Sekler, M Hershfinkel, MD Walker Biochemical and biophysical research communications 335 (1), 97-104, 2005 | 313 | 2005 |
A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport M Hershfinkel, A Moran, N Grossman, I Sekler Proceedings of the National Academy of Sciences 98 (20), 11749-11754, 2001 | 301 | 2001 |
Mechanism and regulation of cellular zinc transport I Sekler, SL Sensi, M Hershfinkel, WF Silverman Molecular medicine 13, 337-343, 2007 | 300 | 2007 |
Synaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus L Besser, E Chorin, I Sekler, WF Silverman, S Atkin, JT Russell, ... Journal of Neuroscience 29 (9), 2890-2901, 2009 | 273 | 2009 |
Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter E Ohana, E Hoch, C Keasar, T Kambe, O Yifrach, M Hershfinkel, I Sekler Journal of Biological Chemistry 284 (26), 17677-17686, 2009 | 228 | 2009 |
NCLX: the mitochondrial sodium calcium exchanger L Boyman, GSB Williams, D Khananshvili, I Sekler, WJ Lederer Journal of molecular and cellular cardiology 59, 205-213, 2013 | 210 | 2013 |
The Mitochondrial Ca2+ Uniporter MCU Is Essential for Glucose-Induced ATP Increases in Pancreatic β-Cells AI Tarasov, F Semplici, MA Ravier, EA Bellomo, TJ Pullen, P Gilon, ... PloS one 7 (7), e39722, 2012 | 204 | 2012 |
The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers TC Pozos, I Seller, MS Cyert Molecular and cellular biology, 1996 | 187 | 1996 |
PKA phosphorylation of NCLX reverses mitochondrial calcium overload and depolarization, promoting survival of PINK1-deficient dopaminergic neurons M Kostic, MHR Ludtmann, H Bading, M Hershfinkel, E Steer, CT Chu, ... Cell reports 13 (2), 376-386, 2015 | 185 | 2015 |
Lithium-calcium exchange is mediated by a distinct potassium-independent sodium-calcium exchanger R Palty, E Ohana, M Hershfinkel, M Volokita, V Elgazar, O Beharier, ... Journal of Biological Chemistry 279 (24), 25234-25240, 2004 | 170 | 2004 |
Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor E Chorin, O Vinograd, I Fleidervish, D Gilad, S Herrmann, I Sekler, ... Journal of Neuroscience 31 (36), 12916-12926, 2011 | 168 | 2011 |
The zinc sensing receptor, a link between zinc and cell signaling M Hershfinkel, WF Silverman, I Sekler Molecular Medicine 13, 331-336, 2007 | 145 | 2007 |
Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity E Hoch, W Lin, J Chai, M Hershfinkel, D Fu, I Sekler Proceedings of the National Academy of Sciences 109 (19), 7202-7207, 2012 | 142 | 2012 |
Zinc released from injured cells is acting via the Zn2+-sensing receptor, ZnR, to trigger signaling leading to epithelial repair H Sharir, A Zinger, A Nevo, I Sekler, M Hershfinkel Journal of Biological Chemistry 285 (34), 26097-26106, 2010 | 137 | 2010 |
LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation MHR Ludtmann, M Kostic, A Horne, S Gandhi, I Sekler, AY Abramov Cell death & disease 10 (4), 265, 2019 | 136* | 2019 |
NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD (P) H production and modulating matrix redox state U De Marchi, J Santo-Domingo, C Castelbou, I Sekler, A Wiederkehr, ... Journal of Biological Chemistry 289 (29), 20377-20385, 2014 | 133 | 2014 |
Mitochondrial calcium dysregulation contributes to dendrite degeneration mediated by PD/LBD-associated LRRK2 mutants M Verma, J Callio, PA Otero, I Sekler, ZP Wills, CT Chu Journal of Neuroscience 37 (46), 11151-11165, 2017 | 130 | 2017 |
ZnT‐1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc C Nolte, A Gore, I Sekler, W Kresse, M Hershfinkel, A Hoffmann, ... Glia 48 (2), 145-155, 2004 | 130 | 2004 |