Extracellular vesicles as drug delivery systems: Why and how? OM Elsharkasy, JZ Nordin, DW Hagey, OG de Jong, RM Schiffelers, ... Advanced drug delivery reviews 159, 332-343, 2020 | 925 | 2020 |
Identification of storage conditions stabilizing extracellular vesicles preparations A Görgens, G Corso, DW Hagey, R Jawad Wiklander, MO Gustafsson, ... Journal of extracellular vesicles 11 (6), e12238, 2022 | 230 | 2022 |
Systematic methodological evaluation of a multiplex bead-based flow cytometry assay for detection of extracellular vesicle surface signatures OPB Wiklander, RB Bostancioglu, JA Welsh, AM Zickler, F Murke, ... Frontiers in immunology 9, 1326, 2018 | 226 | 2018 |
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging D Gupta, X Liang, S Pavlova, OPB Wiklander, G Corso, Y Zhao, O Saher, ... Journal of extracellular vesicles 9 (1), 1800222, 2020 | 172 | 2020 |
Sox2 acts in a dose-dependent fashion to regulate proliferation of cortical progenitors DW Hagey, J Muhr Cell reports 9 (5), 1908-1920, 2014 | 104 | 2014 |
MyT1 counteracts the neural progenitor program to promote vertebrate neurogenesis FF Vasconcelos, A Sessa, C Laranjeira, AASF Raposo, V Teixeira, ... Cell reports 17 (2), 469-483, 2016 | 76 | 2016 |
SOX2 regulates common and specific stem cell features in the CNS and endoderm derived organs DW Hagey, S Klum, I Kurtsdotter, C Zaouter, D Topcic, O Andersson, ... PLoS genetics 14 (2), e1007224, 2018 | 65 | 2018 |
Sequentially acting SOX proteins orchestrate astrocyte‐and oligodendrocyte‐specific gene expression S Klum, C Zaouter, Z Alekseenko, ÅK Björklund, DW Hagey, J Ericson, ... EMBO reports 19 (11), e46635, 2018 | 58 | 2018 |
Targeting OGG1 arrests cancer cell proliferation by inducing replication stress T Visnes, C Benítez-Buelga, A Cázares-Körner, K Sanjiv, BMF Hanna, ... Nucleic acids research 48 (21), 12234-12251, 2020 | 54 | 2020 |
Growth media conditions influence the secretion route and release levels of engineered extracellular vesicles JP Bost, O Saher, D Hagey, DR Mamand, X Liang, W Zheng, G Corso, ... Advanced Healthcare Materials 11 (5), 2101658, 2022 | 47 | 2022 |
SOX5/6/21 prevent oncogene-driven transformation of brain stem cells I Kurtsdotter, D Topcic, A Karlén, B Singla, DW Hagey, M Bergsland, ... Cancer research 77 (18), 4985-4997, 2017 | 46 | 2017 |
Estimating the number of diseases–the concept of rare, ultra-rare, and hyper-rare CIE Smith, P Bergman, DW Hagey IScience 25 (8), 2022 | 42 | 2022 |
Pbx homeodomain proteins pattern both the zebrafish retina and tectum CR French, T Erickson, D Callander, KM Berry, R Koss, DW Hagey, ... BMC developmental biology 7, 1-12, 2007 | 42 | 2007 |
The cellular response to extracellular vesicles is dependent on their cell source and dose DW Hagey, M Ojansivu, BR Bostancioglu, O Saher, JP Bost, ... Science advances 9 (35), eadh1168, 2023 | 41 | 2023 |
Extracellular vesicles are the primary source of blood‐borne tumour‐derived mutant KRAS DNA early in pancreatic cancer DW Hagey, M Kordes, A Görgens, MO Mowoe, JZ Nordin, CF Moro, ... Journal of Extracellular Vesicles 10 (12), e12142, 2021 | 41 | 2021 |
Phenotype-agnostic molecular subtyping of neurodegenerative disorders: The Cincinnati Cohort Biomarker Program (CCBP) A Sturchio, L Marsili, JA Vizcarra, AK Dwivedi, MA Kauffman, AP Duker, ... Frontiers in Aging Neuroscience 12, 553635, 2020 | 36 | 2020 |
CYCLIN-B1/2 and-D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment DW Hagey, D Topcic, N Kee, F Reynaud, M Bergsland, T Perlmann, ... Nature communications 11 (1), 2898, 2020 | 36 | 2020 |
Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells DW Hagey, C Zaouter, G Combeau, MA Lendahl, O Andersson, M Huss, ... Genome research 26 (7), 908-917, 2016 | 31 | 2016 |
The cell cycle and differentiation as integrated processes: Cyclins and CDKs reciprocally regulate Sox and Notch to balance stem cell maintenance J Muhr, DW Hagey Bioessays 43 (7), 2000285, 2021 | 21 | 2021 |
Elevated levels of ZAC1 disrupt neurogenesis and promote rapid in vivo reprogramming V Rraklli, E Södersten, U Nyman, DW Hagey, J Holmberg Stem cell research 16 (1), 1-9, 2016 | 21 | 2016 |