Depletion of human histone H1 variants uncovers specific roles in gene expression and cell growth M Sancho, E Diani, M Beato, A Jordan PLoS genetics 4 (10), e1000227, 2008 | 241 | 2008 |
Mapping of six somatic linker histone H1 variants in human breast cancer cells uncovers specific features of H1. 2 L Millan-Arino, AB Islam, A Izquierdo-Bouldstridge, R Mayor, JM Terme, ... Nucleic acids research 42 (7), 4474-4493, 2014 | 107 | 2014 |
Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes V Andreu-Fernández, M Sancho, A Genovés, E Lucendo, F Todt, ... Proceedings of the National Academy of Sciences 114 (2), 310-315, 2017 | 100 | 2017 |
Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic I Galiana, B Lozano-Torres, M Sancho, M Alfonso, A Bernardos, V Bisbal, ... Journal of Controlled Release 323, 624-634, 2020 | 88 | 2020 |
Understanding MCL1: from cellular function and regulation to pharmacological inhibition M Sancho, D Leiva, E Lucendo, M Orzáez The FEBS Journal 289 (20), 6209-6234, 2022 | 57 | 2022 |
Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases PM Soriano-Teruel, G García‑Laínez, M Marco-Salvador, J Pardo, M Arias, ... Cell death & disease 12 (12), 1155, 2021 | 52 | 2021 |
Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment A García-Fernández, M Sancho, V Bisbal, P Amorós, MD Marcos, ... Journal of Controlled Release 337, 14-26, 2021 | 45 | 2021 |
Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis E Lucendo, M Sancho, F Lolicato, M Javanainen, W Kulig, D Leiva, ... Proceedings of the National Academy of Sciences 117 (45), 27980-27988, 2020 | 38 | 2020 |
Apaf1 inhibition promotes cell recovery from apoptosis A Gortat, M Sancho, L Mondragón, À Messeguer, E Pérez-Payá, ... Protein & cell 6 (11), 833-843, 2015 | 38 | 2015 |
A polymeric nanomedicine diminishes inflammatory events in renal tubular cells AC Ucero, S Berzal, C Ocaña-Salceda, M Sancho, M Orzaez, ... PloS one 8 (1), e51992, 2013 | 38 | 2013 |
Minocycline inhibits cell death and decreases mutant Huntingtin aggregation by targeting Apaf-1 M Sancho, AE Herrera, A Gortat, RJ Carbajo, A Pineda-Lucena, M Orzáez, ... Human Molecular Genetics 20 (18), 3545-3553, 2011 | 37 | 2011 |
Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment M Orzáez, T Guevara, M Sancho, E Pérez-Payá Cell death & disease 3 (10), e415-e415, 2012 | 36 | 2012 |
Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity M Orzaez, M Sancho, S Marchan, L Mondragon, R Montava, JG Valero, ... PloS one 9 (10), e110979, 2014 | 29 | 2014 |
Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications JM Terme, L Millán-Ariño, R Mayor, N Luque, A Izquierdo-Bouldstridge, ... FEBS letters 588 (14), 2353-2362, 2014 | 26 | 2014 |
Optimizing the control of apoptosis by amide/triazole isosteric substitution in a constrained peptoid M Corredor, J Bujons, M Orzáez, M Sancho, E Pérez-Payá, I Alfonso, ... European Journal of Medicinal Chemistry 63, 892-896, 2013 | 24 | 2013 |
Polypeptide modulators of caspase recruitment domain (CARD)-CARD-mediated protein-protein interactions Y Palacios-Rodríguez, G García-Laínez, M Sancho, A Gortat, M Orzáez, ... Journal of Biological Chemistry 286 (52), 44457-44466, 2011 | 21 | 2011 |
BH3-mimetics-and cisplatin-induced cell death proceeds through different pathways depending on the availability of death-related cellular components V Andreu-Fernandez, A Genoves, A Messeguer, M Orzaez, M Sancho, ... PLoS One 8 (2), e56881, 2013 | 19 | 2013 |
Nanodevices for the efficient codelivery of CRISPR-Cas9 editing machinery and an entrapped cargo: a proposal for dual anti-inflammatory therapy A García-Fernández, G Vivo-Llorca, M Sancho, AB García-Jareño, ... Pharmaceutics 14 (7), 1495, 2022 | 16 | 2022 |
Identification of NLRP3PYD Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity S Moasses Ghafary, PM Soriano-Teruel, S Lotfollahzadeh, M Sancho, ... International Journal of Molecular Sciences 23 (3), 1651, 2022 | 16 | 2022 |
Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells M Sancho, A Gortat, AE Herrera, V Andreu-Fernandez, E Ferraro, ... PLoS One 9 (1), e84666, 2014 | 13 | 2014 |