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Michael Keough
Michael Keough
Adresse e-mail validée de ualberta.ca
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Pathophysiology of the brain extracellular matrix: a new target for remyelination
LW Lau, R Cua, MB Keough, S Haylock-Jacobs, VW Yong
Nature Reviews Neuroscience 14 (10), 722-729, 2013
6462013
Expanding antigen-specific regulatory networks to treat autoimmunity
X Clemente-Casares, J Blanco, P Ambalavanan, J Yamanouchi, S Singha, ...
Nature 530 (7591), 434-440, 2016
5252016
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation
A Fernández-Castañeda, P Lu, AC Geraghty, E Song, MH Lee, J Wood, ...
Cell 185 (14), 2452-2468. e16, 2022
4132022
Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination
LW Lau, MB Keough, S Haylock‐Jacobs, R Cua, A Döring, S Sloka, ...
Annals of neurology 72 (3), 419-432, 2012
2782012
An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination
MB Keough, JA Rogers, P Zhang, SK Jensen, EL Stephenson, T Chen, ...
Nature communications 7 (1), 11312, 2016
2312016
Remyelination after spinal cord injury: is it a target for repair?
JR Plemel, MB Keough, GJ Duncan, JS Sparling, VW Yong, PK Stys, ...
Progress in neurobiology 117, 54-72, 2014
2122014
Mechanisms of lysophosphatidylcholine‐induced demyelination: A primary lipid disrupting myelinopathy
JR Plemel, NJ Michaels, N Weishaupt, AV Caprariello, MB Keough, ...
Glia 66 (2), 327-347, 2018
2022018
A critical threshold of rehabilitation involving brain-derived neurotrophic factor is required for poststroke recovery
CL MacLellan, MB Keough, S Granter-Button, GA Chernenko, S Butt, ...
Neurorehabilitation and neural repair 25 (8), 740-748, 2011
1872011
Glioblastoma remodelling of human neural circuits decreases survival
S Krishna, A Choudhury, MB Keough, K Seo, L Ni, S Kakaizada, A Lee, ...
Nature 617 (7961), 599-607, 2023
1692023
Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system
KS Rawji, AMH Young, T Ghosh, NJ Michaels, R Mirzaei, J Kappen, ...
Acta Neuropathologica 139, 893-909, 2020
1272020
Overcoming neurite‐inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix
RC Cua, LW Lau, MB Keough, R Midha, SS Apte, VW Yong
Glia 61 (6), 972-984, 2013
1062013
Experimental demyelination and remyelination of murine spinal cord by focal injection of lysolecithin
MB Keough, SK Jensen, VW Yong
Journal of visualized experiments: JoVE, 52679, 2015
1012015
Laquinimod reduces neuroaxonal injury through inhibiting microglial activation
MK Mishra, J Wang, MB Keough, Y Fan, C Silva, S Sloka, L Hayardeny, ...
Annals of clinical and translational neurology 1 (6), 409-422, 2014
962014
Glioma synapses recruit mechanisms of adaptive plasticity
KR Taylor, T Barron, A Hui, A Spitzer, B Yalçin, AE Ivec, AC Geraghty, ...
Nature 623 (7986), 366-374, 2023
952023
Multimodal enhancement of remyelination by exercise with a pivotal role for oligodendroglial PGC1α
SK Jensen, NJ Michaels, S Ilyntskyy, MB Keough, O Kovalchuk, VW Yong
Cell reports 24 (12), 3167-3179, 2018
912018
Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis
JR Plemel, AV Caprariello, MB Keough, TJ Henry, S Tsutsui, TH Chu, ...
Journal of Cell Biology 216 (4), 1163-1181, 2017
822017
Remyelination therapy for multiple sclerosis
MB Keough, VW Yong
Neurotherapeutics 10 (1), 44-54, 2013
822013
Chondroitin sulphate proteoglycans: extracellular matrix proteins that regulate immunity of the central nervous system
S Haylock-Jacobs, MB Keough, L Lau, VW Yong
Autoimmunity reviews 10 (12), 766-772, 2011
692011
Targeting the chondroitin sulfate proteoglycans: evaluating fluorinated glucosamines and xylosides in screens pertinent to multiple sclerosis
EL Stephenson, P Zhang, S Ghorbani, A Wang, J Gu, MB Keough, ...
ACS Central Science 5 (7), 1223-1234, 2019
402019
Surgical or endovascular management of middle cerebral artery aneurysms: a randomized comparison
TE Darsaut, MB Keough, A Sagga, VKY Chan, A Diouf, W Boisseau, ...
World Neurosurgery 149, e521-e534, 2021
322021
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