Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 121 | 2022 |
Evolutionary dynamics of neoantigens in growing tumors E Lakatos, MJ Williams, RO Schenck, WCH Cross, J Househam, L Zapata, ... Nature genetics 52 (10), 1057-1066, 2020 | 113 | 2020 |
The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022 | 87 | 2022 |
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues C Gabbutt, RO Schenck, DJ Weisenberger, C Kimberley, A Berner, ... Nature biotechnology 40 (5), 720-730, 2022 | 42 | 2022 |
The genomic landscape of 2,023 colorectal cancers AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... Nature 633 (8028), 127-136, 2024 | 29 | 2024 |
Phenotypic noise and plasticity in cancer evolution FJH Whiting, J Househam, AM Baker, A Sottoriva, TA Graham Trends in Cell Biology 34 (6), 451-464, 2024 | 12 | 2024 |
Integrated quality control of allele-specific copy numbers, mutations and tumour purity from cancer whole genome sequencing assays J Househam, R Bergamin, S Milite, N Calonaci, A Antonello, MJ Williams, ... bioRxiv, 2021.02. 13.429885, 2022 | 10* | 2022 |
Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions AJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ... bioRxiv, 2022.11. 16.515599, 2022 | 8 | 2022 |
Factor VIII cross-matches to the human proteome reduce the predicted inhibitor risk in missense mutation hemophilia A DP Hart, N Uzun, S Skelton, A Kakoschke, J Househam, DS Moss, ... Haematologica 104 (3), 599, 2018 | 8 | 2018 |
Computational validation of clonal and subclonal copy number alterations from bulk tumor sequencing using CNAqc A Antonello, R Bergamin, N Calonaci, J Househam, S Milite, MJ Williams, ... Genome Biology 25 (1), 38, 2024 | 2 | 2024 |
Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer E Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ... bioRxiv, 2024 | 1 | 2024 |
Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instability Q Guo, J Househam, E Lakatos, S Nowinski, I Al Bakir, H Grant, ... bioRxiv, 2024.10. 03.616572, 2024 | 1 | 2024 |
Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinoma M Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Salié, ... Research Square, 2023 | 1 | 2023 |
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, C Kimberley, ... bioRxiv, 2021.07. 14.451265, 2021 | 1 | 2021 |
153P Determinants of tumour-immune evolutionary trajectory in colorectal cancer E Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ... Annals of Oncology 35, S68, 2024 | | 2024 |
416P Evolutionary and immune microenvironment dynamics determine response to neoadjuvant treatment of oesophageal adenocarcinoma M Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Salié, ... Annals of Oncology 35, S168-S169, 2024 | | 2024 |
Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma B Bátai, L Kiss, L Varga, Á Nagy, J Househam, AM Baker, T László, ... Modern Pathology 37 (5), 100465, 2024 | | 2024 |
Large-scale, low-cost, and accurate measurement of cancer evolutionary dynamics from clinical patient samples C Gabbutt, M Duran-Ferrer, H Grant, D Mallo, F Nadeu, J Househam, ... Cancer Research 84 (6_Supplement), 4300-4300, 2024 | | 2024 |
Spatially resolving the dynamics of immunoediting in advanced colorectal cancer V Gunasri, N Trahearn, E Lakatos, J Househam, T Heide, GD Cresswell, ... JOURNAL OF PATHOLOGY 261, S29-S29, 2023 | | 2023 |
Evolutionary dynamics of 1,976 lymphoid malignancies predict clinical outcome C Gabbutt, M Duran-Ferrer, H Grant, D Mallo, F Nadeu, J Househam, ... medRxiv, 2023.11. 10.23298336, 2023 | | 2023 |