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Christopher J. Pirozzi
Christopher J. Pirozzi
Adresse e-mail validée de dm.duke.edu
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Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
Y Jiao, PJ Killela, ZJ Reitman, BA Rasheed, CM Heaphy, RF de Wilde, ...
Oncotarget 3 (7), 709, 2012
7082012
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas
PJ Killela, CJ Pirozzi, P Healy, ZJ Reitman, E Lipp, BA Rasheed, R Yang, ...
Oncotarget 5 (6), 1515, 2014
3042014
The implications of IDH mutations for cancer development and therapy
CJ Pirozzi, H Yan
Nature Reviews Clinical Oncology, 1-17, 2021
2652021
KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation
C Guo, LH Chen, Y Huang, CC Chang, P Wang, CJ Pirozzi, X Qin, X Bao, ...
Oncotarget 4 (11), 2144, 2013
1592013
Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target
C Guo, CJ Pirozzi, GY Lopez, H Yan
Current opinion in neurology 24 (6), 648, 2011
1102011
The genetic landscape of anaplastic astrocytoma
PJ Killela, CJ Pirozzi, ZJ Reitman, S Jones, BA Rasheed, E Lipp, ...
Oncotarget 5 (6), 1452, 2014
832014
Cic loss promotes gliomagenesis via aberrant neural stem cell proliferation and differentiation
R Yang, LH Chen, LJ Hansen, AB Carpenter, CJ Moure, H Liu, CJ Pirozzi, ...
Cancer research 77 (22), 6097-6108, 2017
572017
Mutant IDH1 disrupts the mouse subventricular zone and alters brain tumor progression
CJ Pirozzi, AB Carpenter, MS Waitkus, CY Wang, H Zhu, LJ Hansen, ...
Molecular Cancer Research 15 (5), 507-520, 2017
512017
Adaptive evolution of the GDH2 allosteric domain promotes gliomagenesis by resolving IDH1R132H-induced metabolic liabilities
MS Waitkus, CJ Pirozzi, CJ Moure, BH Diplas, LJ Hansen, AB Carpenter, ...
Cancer research 78 (1), 36-50, 2018
462018
MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation
LJ Hansen, R Sun, R Yang, SX Singh, LH Chen, CJ Pirozzi, CJ Moure, ...
Cancer research 79 (13), 3383-3394, 2019
442019
Mutant IDH1 is required for IDH1 mutated tumor cell growth
G Jin, CJ Pirozzi, LH Chen, GY Lopez, CG Duncan, J Feng, I Spasojevic, ...
Oncotarget 3 (8), 774, 2012
412012
Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe
Y Liu, AB Carpenter, CJ Pirozzi, H Yuan, MS Waitkus, Z Zhou, L Hansen, ...
Nanotechnology 30 (27), 275101, 2019
322019
Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors
ZJ Reitman, CJ Pirozzi, H Yan
Acta neuropathologica 126 (6), 789-792, 2013
302013
Releasing the block: setting differentiation free with mutant IDH inhibitors
CJ Pirozzi, ZJ Reitman, H Yan
Cancer cell 23 (5), 570-572, 2013
262013
CRISPR editing of mutant IDH1 R132H induces a CpG methylation-low state in patient-derived glioma models of G-CIMP
CJ Moure, BH Diplas, LH Chen, R Yang, CJ Pirozzi, Z Wang, I Spasojevic, ...
Molecular Cancer Research 17 (10), 2042-2050, 2019
252019
TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist
C Xu, H Liu, CJ Pirozzi, LH Chen, PK Greer, BH Diplas, L Zhang, ...
Acta neuropathologica communications 9 (1), 1-12, 2021
132021
Epigenetic regulation of Fanconi anemia genes implicates PRMT5 blockage as a strategy for tumor chemosensitization
C Du, SW Li, SX Singh, K Roso, MA Sun, CJ Pirozzi, R Yang, JL Li, Y He
Molecular Cancer Research, 2021
102021
Preclinical Immunotherapeutic Animal Models for Brain Tumors
V Chandramohan, L Sanchez-Perez, Y He, CJ Pirozzi, KL Congdon, ...
Translational Immunotherapy of Brain Tumors, 111-147, 2017
42017
Tumor-Specific Mutations in Gliomas and Their Implications for Immunotherapy
CJ Pirozzi, AB Carpenter, T Hennika, OJ Becher, H Yan
Translational Immunotherapy of Brain Tumors, 83-107, 2017
32017
Glioma Research in the era of medical big data
F Wang, CJ Pirozzi, X Li
Cancer Translational Medicine 4 (4), 95, 2018
22018
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