| Transcriptional regulation of autophagy by an FXR–CREB axis S Seok, T Fu, SE Choi, Y Li, R Zhu, S Kumar, X Sun, G Yoon, Y Kang, ... Nature 516 (7529), 108-111, 2014 | 443 | 2014 |
| A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... Nature communications 4 (1), 2035, 2013 | 344 | 2013 |
| Nucleotide excision repair is a potential therapeutic target in multiple myeloma R Szalat, MK Samur, M Fulciniti, M Lopez, P Nanjappa, A Cleynen, K Wen, ... Leukemia 32 (1), 111-119, 2018 | 49 | 2018 |
| Role of apurinic/apyrimidinic nucleases in the regulation of homologous recombination in myeloma: mechanisms and translational significance S Kumar, S Talluri, J Pal, X Yuan, R Lu, P Nanjappa, MK Samur, ... Blood Cancer Journal 8 (10), 92, 2018 | 45 | 2018 |
| Dysregulated APOBEC3G causes DNA damage and promotes genomic instability in multiple myeloma S Talluri, MK Samur, L Buon, S Kumar, LB Potluri, J Shi, RH Prabhala, ... Blood cancer journal 11 (10), 166, 2021 | 37 | 2021 |
| Dual PAK4-NAMPT inhibition impacts growth and survival, and increases sensitivity to DNA-damaging agents in Waldenström Macroglobulinemia N Li, MA Lopez, M Linares, S Kumar, S Oliva, J Martinez-Lopez, L Xu, ... Clinical cancer research 25 (1), 369-377, 2019 | 32 | 2019 |
| Agonist-mediated docking of androgen receptor onto the mitotic chromatin platform discriminates intrinsic mode of action of prostate cancer drugs S Kumar, NK Chaturvedi, S Kumar, RK Tyagi Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (1), 59-73, 2008 | 30 | 2008 |
| Cross-talk between androgen receptor and pregnane and xenobiotic receptor reveals existence of a novel modulatory action of anti-androgenic drugs S Kumar, B Jaiswal, S Kumar, S Negi, RK Tyagi Biochemical pharmacology 80 (7), 964-976, 2010 | 26 | 2010 |
| The roles of homologous recombination and the immune system in the genomic evolution of cancer B Nandi, S Talluri, S Kumar, C Yenumula, JS Gold, R Prabhala, ... Journal of translational science 5 (2), 10.15761/JTS. 1000282, 2018 | 21 | 2018 |
| Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma DA Alagpulinsa, S Kumar, S Talluri, P Nanjappa, L Buon, C Chakraborty, ... Blood Advances 3 (23), 3968-3972, 2019 | 13 | 2019 |
| Impact of RAD51C-mediated homologous recombination on genomic integrity in Barrett’s adenocarcinoma cells J Pal, P Nanjappa, S Kumar, J Shi, L Buon, NC Munshi, MA Shammas Journal of gastroenterology and hepatology research 6 (1), 2286, 2017 | 13 | 2017 |
| Integrated genomics and comprehensive validation reveal drivers of genomic evolution in esophageal adenocarcinoma S Kumar, L Buon, S Talluri, M Roncador, C Liao, J Zhao, J Shi, ... Communications Biology 4 (1), 617, 2021 | 10 | 2021 |
| Rad51 is implicated in DNA damage, Chemoresistance and immune dysregulation in solid tumors C Liao, S Talluri, J Zhao, S Mu, S Kumar, J Shi, L Buon, NC Munshi, ... Cancers 14 (22), 5697, 2022 | 9 | 2022 |
| Elevated APE1 dysregulates homologous recombination and cell cycle driving genomic evolution, tumorigenesis, and chemoresistance in esophageal adenocarcinoma S Kumar, J Zhao, S Talluri, L Buon, S Mu, LB Potluri, C Liao, J Shi, ... Gastroenterology 165 (2), 357-373, 2023 | 6 | 2023 |
| RAD51 inhibitor reverses etoposide-induced genomic toxicity and instability in esophageal adenocarcinoma cells C Liao, J Zhao, S Kumar, C Chakraborty, S Talluri, NC Munshi, ... Archives of clinical toxicology 2 (1), 3, 2020 | 6 | 2020 |
| Stable cellular models of nuclear receptor PXR for high-throughput evaluation of small molecules S Negi, SK Singh, S Kumar, S Kumar, RK Tyagi Toxicology in Vitro 52, 222-234, 2018 | 4 | 2018 |
| Risk assessment to evaluate if crayons complying with the Consumer Product Safety Improvement Act of 2008 for Lead, also comply with California Proposition 65 GR Ahmad, S Kumar, D Ahmad, MA Shammas Frontiers in Public Health 5, 130, 2017 | 3 | 2017 |
| Elevated APE1 mediates dysregulation of homologous recombination in myeloma: mechanisms and translational significance S Kumar, M Gkotzamanidou, J Pal, R Lu, P Nanjappa, J Shi, M Shammas, ... Blood 124 (21), 2074, 2014 | 3 | 2014 |
| Apurinic/apyrimidinic nuclease 1 drives genomic evolution contributing to chemoresistance and tumorigenesis in solid tumor S Kumar, J Zhao, S Talluri, L Buon, S Mu, B Potluri, C Liao, J Shi, ... bioRxiv, 2022.04. 20.488830, 2022 | 2 | 2022 |
| Nuclease activity is associated with genomic instability as well as survival in myeloma; underlying mechanisms and significance MA Shammas, L Buon, J Lin, MK Samur, JM Patel, A Vahia, P Nanjappa, ... Blood 126 (23), 2420, 2015 | 2 | 2015 |
Purushothama NanjappaLead Research Associate, Dana Farber Cancer Institute/Harvard Medical schoolAdresse e-mail validée de dfci.harvard.edu
