| Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing SK Leung, AR Jeffries, I Castanho, BT Jordan, K Moore, JP Davies, ... Cell reports 37 (7), 2021 | 117 | 2021 |
| Transcriptional signatures of tau and amyloid neuropathology I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ... Cell reports 30 (6), 2040-2054. e5, 2020 | 60 | 2020 |
| Characterizing the properties of bisulfite sequencing data: maximizing power and sensitivity to identify between-group differences in DNA methylation D Seiler Vellame, I Castanho, A Dahir, J Mill, E Hannon BMC genomics 22, 1-16, 2021 | 25 | 2021 |
| Phospholipase D1 ablation disrupts mouse longitudinal hippocampal axis organization and functioning L Santa-Marinha, I Castanho, RR Silva, FV Bravo, AM Miranda, T Meira, ... Cell reports 30 (12), 4197-4208. e6, 2020 | 22 | 2020 |
| Epigenetic processes in Alzheimer's disease I Castanho, K Lunnon Chromatin Signaling and Neurological Disorders, 153-180, 2019 | 15 | 2019 |
| Full-length transcript sequencing of human and mouse identifies widespread isoform diversity and alternative splicing in the cerebral cortex AR Jeffries, SK Leung, I Castanho, K Moore, JP Davies, EL Dempster, ... bioRxiv, 2020.10. 14.339200, 2020 | 9 | 2020 |
| Novel CYP1B1-RMDN2 Alzheimer’s disease locus identified by genome-wide association analysis of cerebral tau deposition on PET K Nho, SL Risacher, L Apostolova, PJ Bice, J Brosch, R Deardorff, ... medRxiv, 2023.02. 27.23286048, 2023 | 4 | 2023 |
| The Neuroepigenetic Landscape of Vertebrate and Invertebrate Models of Neurodegenerative Diseases TH Sundaramoorthy, I Castanho Epigenetics Insights 15, 25168657221135848, 2022 | 4 | 2022 |
| Transcriptional signatures of tau and amyloid neuropathology. Cell Rep 30: 2040–2054. e5 I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ... | 4 | 2020 |
| Long-read transcript sequencing identifies differential isoform expression in the entorhinal cortex in a transgenic model of tau pathology SK Leung, RA Bamford, AR Jeffries, I Castanho, B Chioza, CS Flaxman, ... Nature Communications 15 (1), 6458, 2024 | 3 | 2024 |
| Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson’s disease: A DNA co-methylation network analysis J Harvey, AR Smith, LS Weymouth, RG Smith, I Castanho, L Hubbard, ... Research Square, 2023 | 2 | 2023 |
| CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET K Nho, SL Risacher, LG Apostolova, PJ Bice, JR Brosch, R Deardorff, ... Nature Communications 15 (1), 8251, 2024 | 1 | 2024 |
| Understanding Alzheimer’s disease resilience at the cellular level I Castanho, PN Yeganeh, S Shah, D Prokopenko, R Tanzi, W Hide, ... Alzheimer's Association International Conference, 2022 | 1 | 2022 |
| Fluorescence-activated nuclei sorting (FANS) of purified neural cell populations from mouse cortex for multi-omic profiling SS Policicchio, I Castanho, B Chioza, J Burrage, J Mill, EL Dempster, ... | 1 | 2022 |
| Functional genomic characterisation of animal models of AD: relevance to human dementia I Castanho PQDT-UK & Ireland, 2019 | 1 | 2019 |
| Transcriptional signatures of progressive neuropathology in transgenic tau and amyloid mouse models I Castanho, TK Murray, E Hannon, A Jeffries, E Walker, E Laing, H Baulf, ... bioRxiv, 548578, 2019 | 1 | 2019 |
| Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease I Castanho, PN Yeganeh, CA Boix, SL Morgan, H Mathys, D Prokopenko, ... bioRxiv, 2025.01. 13.632801, 2025 | | 2025 |
| Deciphering the molecular and cellular underpinnings of cognitive resilience in Alzheimer’s disease I Castanho, PN Yeganeh, CA Boix, H Mathys, D Prokopenko, B White, ... Alzheimer's & Dementia 20, e090374, 2024 | | 2024 |
| Isoform characterisation & splicing signatures of AD‐risk genes using long‐read sequencing SK Leung, I Castanho, A Jeffries, K Moore, E Dempster, JT Brown, ... Alzheimer's & Dementia 19, e074237, 2023 | | 2023 |
| Epigenetic insights into neuropsychiatric and cognitive symptoms in Parkinson's disease: A DNA co-methylation network analysis K Lunnon, J Harvey, A Smith, L Weymouth, R Smith, I Castanho, ... | | 2023 |
Jonathan MillProfessor of Epigenetics, University of Exeter and King's College LondonAdresse e-mail validée de exeter.ac.uk
