Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function M Piwecka, P Glažar, LR Hernandez-Miranda, S Memczak, SA Wolf, ... Science 357 (6357), eaam8526, 2017 | 1143 | 2017 |
An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration SM Lehmann, C Krüger, B Park, K Derkow, K Rosenberger, J Baumgart, ... Nature neuroscience 15 (6), 827-835, 2012 | 837 | 2012 |
Clathrin regenerates synaptic vesicles from endosomes S Watanabe, T Trimbuch, M Camacho-Pérez, BR Rost, B Brokowski, ... Nature 515 (7526), 228-233, 2014 | 341 | 2014 |
A vicious cycle involving release of heat shock protein 60 from injured cells and activation of toll-like receptor 4 mediates neurodegeneration in the CNS S Lehnardt, E Schott, T Trimbuch, D Laubisch, C Krueger, G Wulczyn, ... Journal of Neuroscience 28 (10), 2320-2331, 2008 | 327 | 2008 |
Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses NL Kononenko, D Puchkov, GA Classen, AM Walter, A Pechstein, ... Neuron 82 (5), 981-988, 2014 | 234 | 2014 |
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling T Trimbuch, P Beed, J Vogt, S Schuchmann, N Maier, M Kintscher, ... Cell 138 (6), 1222-1235, 2009 | 172 | 2009 |
Should I stop or should I go? The role of complexin in neurotransmitter release T Trimbuch, C Rosenmund Nature Reviews Neuroscience 17 (2), 118-125, 2016 | 163 | 2016 |
Synaptotagmin-1 drives synchronous Ca2+-triggered fusion by C2B-domain-mediated synaptic-vesicle-membrane attachment S Chang, T Trimbuch, C Rosenmund Nature neuroscience 21 (1), 33-40, 2018 | 154 | 2018 |
Functional synergy between the Munc13 C-terminal C1 and C2 domains X Liu, AB Seven, M Camacho, V Esser, J Xu, T Trimbuch, B Quade, L Su, ... elife 5, e13696, 2016 | 127 | 2016 |
Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN J Xu, M Camacho, Y Xu, V Esser, X Liu, T Trimbuch, YZ Pan, C Ma, ... Elife 6, e22567, 2017 | 124 | 2017 |
Synaptojanin and endophilin mediate neck formation during ultrafast endocytosis S Watanabe, LE Mamer, S Raychaudhuri, D Luvsanjav, J Eisen, ... Neuron 98 (6), 1184-1197. e6, 2018 | 116 | 2018 |
RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses MK Grauel, M Maglione, S Reddy-Alla, CG Willmes, MM Brockmann, ... Proceedings of the National Academy of Sciences 113 (41), 11615-11620, 2016 | 110 | 2016 |
Membrane bridging by Munc13-1 is crucial for neurotransmitter release B Quade, M Camacho, X Zhao, M Orlando, T Trimbuch, J Xu, W Li, ... Elife 8, e42806, 2019 | 108 | 2019 |
Distinct functions of syntaxin-1 in neuronal maintenance, synaptic vesicle docking, and fusion in mouse neurons G Vardar, S Chang, M Arancillo, YJ Wu, T Trimbuch, C Rosenmund Journal of Neuroscience 36 (30), 7911-7924, 2016 | 102 | 2016 |
Human endogenous retrovirus HERV-K (HML-2) RNA causes neurodegeneration through Toll-like receptors P Dembny, AG Newman, M Singh, M Hinz, M Szczepek, C Krüger, ... JCI insight 5 (7), 2020 | 100 | 2020 |
Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming M Camacho, J Basu, T Trimbuch, S Chang, C Pulido-Lozano, SS Chang, ... Nature communications 8 (1), 15293, 2017 | 94 | 2017 |
Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture MA Herman, F Ackermann, T Trimbuch, C Rosenmund Journal of Neuroscience 34 (35), 11781-11791, 2014 | 93 | 2014 |
Role of the transmembrane potential in the membrane proton leak A Rupprecht, EA Sokolenko, V Beck, O Ninnemann, M Jaburek, ... Biophysical Journal 98 (8), 1503-1511, 2010 | 92 | 2010 |
Re-examining how complexin inhibits neurotransmitter release T Trimbuch, J Xu, D Flaherty, DR Tomchick, J Rizo, C Rosenmund Elife 3, e02391, 2014 | 88 | 2014 |
Titration of Syntaxin1 in mammalian synapses reveals multiple roles in vesicle docking, priming, and release probability M Arancillo, SW Min, S Gerber, A Münster-Wandowski, YJ Wu, M Herman, ... Journal of Neuroscience 33 (42), 16698-16714, 2013 | 83 | 2013 |