| Retinoic acid signaling pathways in development and diseases BC Das, P Thapa, R Karki, S Das, S Mahapatra, TC Liu, I Torregroza, ... Bioorganic & medicinal chemistry 22 (2), 673-683, 2014 | 328 | 2014 |
| Boron chemicals in diagnosis and therapeutics BC Das, P Thapa, R Karki, C Schinke, S Das, S Kambhampati, ... Future medicinal chemistry 5 (6), 653-676, 2013 | 300 | 2013 |
| Synthesis of 2, 6-diaryl-substituted pyridines and their antitumor activities JK Son, LX Zhao, A Basnet, P Thapa, R Karki, Y Na, Y Jahng, TC Jeong, ... European journal of medicinal chemistry 43 (4), 675-682, 2008 | 186 | 2008 |
| 2, 4, 6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship A Basnet, P Thapa, R Karki, Y Na, Y Jahng, BS Jeong, TC Jeong, CS Lee, ... Bioorganic & medicinal chemistry 15 (13), 4351-4359, 2007 | 165 | 2007 |
| Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2, 4-diphenyl-6-aryl pyridines R Karki, P Thapa, MJ Kang, TC Jeong, JM Nam, HL Kim, Y Na, WJ Cho, ... Bioorganic & medicinal chemistry 18 (9), 3066-3077, 2010 | 119 | 2010 |
| A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases HB Kwon, C Park, KH Jeon, E Lee, SE Park, KY Jun, TM Kadayat, ... Journal of Medicinal Chemistry 58 (3), 1100-1122, 2015 | 107 | 2015 |
| Design, synthesis, and antitumor evaluation of 2, 4, 6-triaryl pyridines containing chlorophenyl and phenolic moiety P Thapa, R Karki, M Yun, TM Kadayat, E Lee, HB Kwon, Y Na, WJ Cho, ... European journal of medicinal chemistry 52, 123-136, 2012 | 79 | 2012 |
| Dihydroxylated 2, 4, 6-triphenyl pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study R Karki, P Thapa, HY Yoo, TM Kadayat, PH Park, Y Na, E Lee, KH Jeon, ... European journal of medicinal chemistry 49, 219-228, 2012 | 75 | 2012 |
| 2-Thienyl-4-furyl-6-aryl pyridine derivatives: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study P Thapa, R Karki, U Thapa, Y Jahng, MJ Jung, JM Nam, Y Na, Y Kwon, ... Bioorganic & medicinal chemistry 18 (1), 377-386, 2010 | 74 | 2010 |
| Synthesis of 2, 4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship U Thapa, P Thapa, R Karki, M Yun, JH Choi, Y Jahng, E Lee, KH Jeon, ... European journal of medicinal chemistry 46 (8), 3201-3209, 2011 | 61 | 2011 |
| 2, 6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure–activity relationship, and docking study A Basnet, P Thapa, R Karki, H Choi, JH Choi, M Yun, BS Jeong, Y Jahng, ... Bioorganic & medicinal chemistry letters 20 (1), 42-47, 2010 | 58 | 2010 |
| Synthesis of 2-(thienyl-2-yl or-3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure … P Thapa, R Karki, H Choi, JH Choi, M Yun, BS Jeong, MJ Jung, JM Nam, ... Bioorganic & Medicinal Chemistry 18 (6), 2245-2254, 2010 | 53 | 2010 |
| Folate-PEG conjugates of a far-red light-activatable paclitaxel prodrug to improve selectivity toward folate receptor-positive cancer cells P Thapa, M Li, R Karki, M Bio, P Rajaputra, G Nkepang, S Woo, Y You ACS omega 2 (10), 6349-6360, 2017 | 44 | 2017 |
| Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2, 6-diphenyl-4-aryl pyridines R Karki, C Song, TM Kadayat, TBT Magar, G Bist, A Shrestha, Y Na, ... Bioorganic & medicinal chemistry 23 (13), 3638-3654, 2015 | 38 | 2015 |
| Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2, 4, 6-triphenyl pyridines as potent and selective topoisomerase II inhibitors R Karki, C Park, KY Jun, JG Jee, JH Lee, P Thapa, TM Kadayat, Y Kwon, ... European journal of medicinal chemistry 84, 555-565, 2014 | 38 | 2014 |
| Discovery of dihydroxylated 2, 4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor KY Jun, H Kwon, SE Park, E Lee, R Karki, P Thapa, JH Lee, ES Lee, ... European journal of medicinal chemistry 80, 428-438, 2014 | 38 | 2014 |
| Synthesis and biological activity of 2, 4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison R Karki, C Park, KY Jun, TM Kadayat, ES Lee, Y Kwon European Journal of Medicinal Chemistry 90, 360-378, 2015 | 35 | 2015 |
| Use of zebrafish in chemical biology and drug discovery BC Das, L McCormick, P Thapa, R Karki, T Evans Future medicinal chemistry 5 (17), 2103-2116, 2013 | 32 | 2013 |
| Synthesis, Topoisomerase I and II Inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2, 4, 6-trisubstituted pyridine containing … BS Jeong, HY Choi, P Thapa, R Karki, EY Lee, JM Nam, YH Na, EM Ha, ... Bulletin of the Korean Chemical Society 32 (1), 303-306, 2011 | 30 | 2011 |
| Modification of C11, C28, C2, 3, 23 or C2, 23, 28 functional groups on asiatic acid and evaluation of hepatoprotective effects LX Zhao, H Park, S Jew, MK Lee, YC Kim, P Thapa, R Karki, YD Jahng, ... Bulletin of the Korean Chemical Society 28 (6), 970-976, 2007 | 30 | 2007 |
Pritam ThapaKansas City VA Medical CenterAdresse e-mail validée de va.gov
