Stapled helical peptides bearing different anchoring residues X Li, S Chen, WD Zhang, HG Hu Chemical Reviews 120 (18), 10079-10144, 2020 | 215 | 2020 |
A PROTAC peptide induces durable β-catenin degradation and suppresses Wnt-dependent intestinal cancer H Liao, X Li, L Zhao, Y Wang, X Wang, Y Wu, X Zhou, W Fu, L Liu, HG Hu, ... Cell discovery 6 (1), 35, 2020 | 109 | 2020 |
Spirolactonized Si-rhodamine: a novel NIR fluorophore utilized as a platform to construct Si-rhodamine-based probes T Wang, QJ Zhao, HG Hu, SC Yu, X Liu, L Liu, QY Wu Chemical Communications 48 (70), 8781-8783, 2012 | 108 | 2012 |
Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis X Chen, X Zhi, P Pan, J Cui, L Cao, W Weng, Q Zhou, L Wang, X Zhai, ... The FASEB Journal 31 (11), 4855, 2017 | 92 | 2017 |
New triazole derivatives as antifungal agents: Synthesis via click reaction, in vitro evaluation and molecular docking studies Y Zou, Q Zhao, J Liao, H Hu, S Yu, X Chai, M Xu, Q Wu Bioorganic & medicinal chemistry letters 22 (8), 2959-2962, 2012 | 85 | 2012 |
Synthesis, antifungal activities and molecular docking studies of novel 2-(2, 4-difluorophenyl)-2-hydroxy-3-(1H-1, 2, 4-triazol-1-yl) propyl dithiocarbamates Y Zou, S Yu, R Li, Q Zhao, X Li, M Wu, T Huang, X Chai, H Hu, Q Wu European Journal of Medicinal Chemistry 74, 366-374, 2014 | 77 | 2014 |
Synthesis and in vitro inhibitory activity of matrine derivatives towards pro-inflammatory cytokines H Hu, S Wang, C Zhang, L Wang, L Ding, J Zhang, Q Wu Bioorganic & medicinal chemistry letters 20 (24), 7537-7539, 2010 | 71 | 2010 |
Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains L Lu, X Zhai, X Li, S Wang, L Zhang, L Wang, X Jin, L Liang, Z Deng, Z Li, ... Nature Communications 13 (1), 4672, 2022 | 65 | 2022 |
Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design X Li, WD Tolbert, HG Hu, N Gohain, Y Zou, F Niu, WX He, W Yuan, JC Su, ... Chemical Science 10 (5), 1522-1530, 2019 | 65 | 2019 |
Design, synthesis, and biological evaluation of novel 1-(1H-1, 2, 4-triazole-1-yl)-2-(2, 4-difluorophenyl)-3-substituted benzylamino-2-propanols X Chai, J Zhang, S Yu, H Hu, Y Zou, Q Zhao, Z Dan, D Zhang, Q Wu Bioorganic & medicinal chemistry letters 19 (6), 1811-1814, 2009 | 62 | 2009 |
Robust biological fibers based on widely available proteins: facile fabrication and suturing application J Zhang, J Sun, B Li, C Yang, J Shen, N Wang, R Gu, D Wang, D Chen, ... Small 16 (8), 1907598, 2020 | 60 | 2020 |
Synthesis of and Specific Antibody Generation for Glycopeptides with Arginine N‐GlcNAcylation M Pan, S Li, X Li, F Shao, L Liu, HG Hu Angewandte Chemie International Edition 53 (52), 14517-14521, 2014 | 60 | 2014 |
Bioactive compound reveals a novel function for ribosomal protein S5 in hepatic stellate cell activation and hepatic fibrosis WH Xu, HG Hu, Y Tian, SZ Wang, J Li, JZ Li, X Deng, H Qian, L Qiu, ZL Hu, ... Hepatology 60 (2), 648-660, 2014 | 58 | 2014 |
Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14α-demethylase S Yu, X Chai, H Hu, Y Yan, Z Guan, Y Zou, Q Sun, Q Wu European journal of medicinal chemistry 45 (10), 4435-4445, 2010 | 57 | 2010 |
RETRACTED ARTICLE: Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis X Chen, X Zhi, L Cao, W Weng, P Pan, H Hu, C Liu, Q Zhao, Q Zhou, J Cui, ... Cell death & disease 8 (9), e3037-e3037, 2017 | 52 | 2017 |
A novel peptide stapling strategy enables the retention of ring-closing amino acid side chains for the Wnt/β-catenin signalling pathway Y Wu, YH Li, X Li, Y Zou, HL Liao, L Liu, YG Chen, D Bierer, HG Hu Chemical Science 8 (11), 7368-7373, 2017 | 52 | 2017 |
Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14α-demethylase X Chai, J Zhang, H Hu, S Yu, Q Sun, Z Dan, Y Jiang, Q Wu European journal of medicinal chemistry 44 (5), 1913-1920, 2009 | 52 | 2009 |
DUCNP@ Mn–MOF/FOE as a highly selective and bioavailable drug delivery system for synergistic combination cancer therapy X Zhao, S He, B Li, B Liu, Y Shi, W Cong, F Gao, J Li, F Wang, K Liu, ... Nano Letters 23 (3), 863-871, 2023 | 51 | 2023 |
X-3, a mangiferin derivative, stimulates AMP-activated protein kinase and reduces hyperglycemia and obesity in db/db mice J Han, J Yi, F Liang, B Jiang, Y Xiao, S Gao, N Yang, H Hu, WF Xie, ... Molecular and Cellular Endocrinology 405, 63-73, 2015 | 51 | 2015 |
Recent advances in chemical protein synthesis: method developments and biological applications S Dong, JS Zheng, Y Li, H Wang, G Chen, Y Chen, G Fang, J Guo, C He, ... Science China Chemistry 67 (4), 1060-1096, 2024 | 49 | 2024 |