Differentiated smooth muscle cells generate a subpopulation of resident vascular progenitor cells in the adventitia regulated by Klf4 MW Majesky, H Horita, A Ostriker, S Lu, JN Regan, A Bagchi, XR Dong, ... Circulation research 120 (2), 296-311, 2017 | 201 | 2017 |
Alcohol activates TGF‐beta but inhibits BMP receptor‐mediated Smad signaling and Smad4 binding to hepcidin promoter in the liver LN Gerjevic, N Liu, S Lu, DD Harrison-Findik International journal of hepatology 2012 (1), 459278, 2012 | 65 | 2012 |
Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis S Lu, AJ Jolly, KA Strand, AM Dubner, MF Mutryn, KS Moulton, ... JCI insight 5 (23), 2020 | 52 | 2020 |
FoxO3 increases miR-34a to cause palmitate-induced cholangiocyte lipoapoptosis SK Natarajan, BA Stringham, AM Mohr, CJ Wehrkamp, S Lu, MA Phillippi, ... Journal of lipid research 58 (5), 866-875, 2017 | 48 | 2017 |
PTEN (phosphatase and tensin homolog) protects against Ang II (Angiotensin II)-induced pathological vascular fibrosis and remodeling—brief report S Lu, KA Strand, MF Mutryn, RM Tucker, AJ Jolly, SB Furgeson, ... Arteriosclerosis, thrombosis, and vascular biology 40 (2), 394-403, 2020 | 44 | 2020 |
PTEN deficiency promotes pathological vascular remodeling of human coronary arteries KS Moulton, M Li, K Strand, S Burgett, P McClatchey, R Tucker, ... JCI insight 3 (4), 2018 | 41 | 2018 |
Autophagy and cancer SZ Lu, DD Harrison-Findik World journal of biological chemistry 4 (3), 64, 2013 | 36 | 2013 |
TLR4 signaling and the inhibition of liver hepcidin expression by alcohol E Zmijewski, S Lu, DD Harrison-Findik World Journal of Gastroenterology: WJG 20 (34), 12161, 2014 | 34 | 2014 |
The effect of alcohol and hydrogen peroxide on liver hepcidin gene expression in mice lacking antioxidant enzymes, glutathione peroxidase-1 or catalase DD Harrison-Findik, S Lu Biomolecules 5 (2), 793-807, 2015 | 31 | 2015 |
Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodelling AJ Jolly, S Lu, KA Strand, AM Dubner, MF Mutryn, RA Nemenoff, ... Cardiovascular Research 118 (6), 1452-1465, 2022 | 29 | 2022 |
High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog) Central Role for … KA Strand, S Lu, MF Mutryn, L Li, Q Zhou, BT Enyart, AJ Jolly, AM Dubner, ... Arteriosclerosis, Thrombosis, and Vascular Biology 40 (8), 1854-1869, 2020 | 27 | 2020 |
Saturated fatty acids induce post-transcriptional regulation of HAMP mRNA via AU-rich element-binding protein, human antigen R (HuR) S Lu, JL Mott, DD Harrison-Findik Journal of Biological Chemistry 290 (40), 24178-24189, 2015 | 26 | 2015 |
Regulation of heme oxygenase expression by alcohol, hypoxia and oxidative stress LN Gerjevic, S Lu, JP Chaky, DD Harrison-Findik World Journal of Biological Chemistry 2 (12), 252, 2011 | 25 | 2011 |
Ceramide induces human hepcidin gene transcription through JAK/STAT3 pathway S Lu, SK Natarajan, JL Mott, KK Kharbanda, DD Harrison-Findik PLoS One 11 (1), e0147474, 2016 | 23 | 2016 |
Lack of hepcidin expression attenuates steatosis and causes fibrosis in the liver S Lu, RG Bennett, KK Kharbanda, DD Harrison-Findik World Journal of Hepatology 8 (4), 211, 2016 | 20 | 2016 |
Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response EK Kleczko, AT Le, TK Hinz, TT Nguyen, A Navarro, CJ Hu, AM Selman, ... Cancer letters 556, 216062, 2023 | 17 | 2023 |
Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis AJ Jolly, S Lu, AM Dubner, KA Strand, MF Mutryn, A Pilotti-Riley, ... JCI insight 8 (9), 2023 | 16 | 2023 |
Inductively coupled mass spectrometry analysis of biometals in conditional Hamp1 and Hamp1 and Hamp2 transgenic mouse models S Lu, J Seravalli, D Harrison-Findik Transgenic research 24, 765-773, 2015 | 14 | 2015 |
Effect of alcohol exposure on hepatic superoxide generation and hepcidin expression DD Harrison-Findik, S Lu, EM Zmijewski, J Jones, MC Zimmerman World Journal of Biological Chemistry 4 (4), 119, 2013 | 12 | 2013 |
Smooth muscle–derived adventitial progenitor cells direct atherosclerotic plaque composition complexity in a Klf4-dependent manner AM Dubner, S Lu, AJ Jolly, KA Strand, MF Mutryn, T Hinthorn, T Noble, ... JCI insight 8 (22), 2023 | 8 | 2023 |