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Roman Barth
Roman Barth
Postdoc | Schmidt Science Fellow 2024 | Institute for Protein Design | University of Washington
Adresse e-mail validée de uw.edu
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SMC complexes can traverse physical roadblocks bigger than their ring size
B Pradhan, R Barth, E Kim, IF Davidson, B Bauer, T van Laar, W Yang, ...
Cell reports 41 (3), 2022
1102022
CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion
IF Davidson, R Barth, M Zaczek, J van der Torre, W Tang, K Nagasaka, ...
Nature 616 (7958), 822-827, 2023
1052023
Formation of correlated chromatin domains at nanoscale dynamic resolution during transcription
HA Shaban, R Barth, K Bystricky
Nucleic acids research 46 (13), e77-e77, 2018
1042018
Hi-D: nanoscale mapping of nuclear dynamics in single living cells
HA Shaban, R Barth, L Recoules, K Bystricky
Genome biology 21 (1), 95, 2020
912020
Coupling chromatin structure and dynamics by live super-resolution imaging
R Barth, K Bystricky, HA Shaban
Science advances 6 (27), eaaz2196, 2020
802020
Looping the genome with SMC complexes
E Kim, R Barth, C Dekker
Annual review of biochemistry 92 (1), 15-41, 2023
452023
ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment
M Tišma, M Panoukidou, H Antar, YM Soh, R Barth, B Pradhan, A Barth, ...
Science advances 8 (26), eabn3299, 2022
372022
Navigating the crowd: visualizing coordination between genome dynamics, structure, and transcription
HA Shaban, R Barth, K Bystricky
Genome biology 21 (1), 278, 2020
362020
Dynamics as a cause for the nanoscale organization of the genome
R Barth, G Fourel, HA Shaban
Nucleus 11 (1), 83-98, 2020
212020
Single-molecule visualization of twin-supercoiled domains generated during transcription
R Janissen, R Barth, M Polinder, J van der Torre, C Dekker
Nucleic acids research 52 (4), 1677-1687, 2024
192024
Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation
M Tišma, R Janissen, H Antar, A Martin-Gonzalez, R Barth, T Beekman, ...
Nucleic acids research 51 (21), 11856-11875, 2023
182023
Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments
R Barth, B Pradhan, E Kim, IF Davidson, J van der Torre, JM Peters, ...
Scientific reports 13 (1), 8100, 2023
132023
Dynamin A as a one-component division machinery for synthetic cells
N De Franceschi, R Barth, S Meindlhumer, A Fragasso, C Dekker
Nature Nanotechnology 19 (1), 70-76, 2024
122024
Spatially coherent diffusion of human RNA Pol II depends on transcriptional state rather than chromatin motion
R Barth, HA Shaban
Nucleus 13 (1), 196-204, 2022
122022
SMC motor proteins extrude DNA asymmetrically and contain a direction switch
R Barth, IF Davidson, J van der Torre, M Taschner, S Gruber, JM Peters, ...
BioRxiv, 2023.12. 21.572892, 2023
112023
Nanoscale mapping of DNA dynamics reveals activity-driven genome organization in living human cells
HA Shaban, R Barth, K Bystricky
bioRxiv, 405969, 2018
112018
All eukaryotic SMC proteins induce a twist of− 0.6 at each DNA loop extrusion step
R Janissen, R Barth, IF Davidson, JM Peters, C Dekker
Science Advances 10 (50), eadt1832, 2024
102024
Cohesin supercoils DNA during loop extrusion
IF Davidson, R Barth, S Horn, R Janissen, K Nagasaka, G Wutz, ...
bioRxiv, 2024.03. 22.586228, 2024
72024
SMC complexes can traverse physical roadblocks bigger than their ring size. Cell Rep. 41, 111491
B Pradhan, R Barth, E Kim, IF Davidson, B Bauer, T van Laar, W Yang, ...
72022
Telomere protein arrays stall DNA loop extrusion by condensin
BT Analikwu, A Deshayes, J van der Torre, T Guérin, AJ Katan, C Béneut, ...
BioRxiv, 2023.10. 29.564563, 2023
62023
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