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Sean Sheehy
Sean Sheehy
Toxicology Research Scientist, Vertex Pharmaceuticals
Adresse e-mail validée de vrtx.com - Page d'accueil
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Muscular thin films for building actuators and powering devices
AW Feinberg, A Feigel, SS Shevkoplyas, S Sheehy, GM Whitesides, ...
Science 317 (5843), 1366-1370, 2007
8712007
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells
BM Maoz, A Herland, EA FitzGerald, T Grevesse, C Vidoudez, ...
Nature biotechnology 36 (9), 865-874, 2018
4202018
Sarcomere alignment is regulated by myocyte shape
MA Bray, SP Sheehy, KK Parker
Cell motility and the cytoskeleton 65 (8), 641-651, 2008
3072008
Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture
AW Feinberg, PW Alford, H Jin, CM Ripplinger, AA Werdich, SP Sheehy, ...
Biomaterials 33 (23), 5732-5741, 2012
3042012
Biohybrid thin films for measuring contractility in engineered cardiovascular muscle
PW Alford, AW Feinberg, SP Sheehy, KK Parker
Biomaterials 31 (13), 3613-3621, 2010
2352010
A tissue-engineered scale model of the heart ventricle
LA MacQueen, SP Sheehy, CO Chantre, JF Zimmerman, FS Pasqualini, ...
Nature biomedical engineering 2 (12), 930-941, 2018
2132018
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip
ML McCain, SP Sheehy, A Grosberg, JA Goss, KK Parker
Proceedings of the National Academy of Sciences 110 (24), 9770-9775, 2013
1692013
Self-organization of muscle cell structure and function
A Grosberg, PL Kuo, CL Guo, NA Geisse, MA Bray, WJ Adams, ...
PLoS computational biology 7 (2), e1001088, 2011
1562011
Myocyte shape regulates lateral registry of sarcomeres and contractility
PL Kuo, H Lee, MA Bray, NA Geisse, YT Huang, WJ Adams, SP Sheehy, ...
The American journal of pathology 181 (6), 2030-2037, 2012
1552012
Fibrous scaffolds for building hearts and heart parts
AK Capulli, LA MacQueen, SP Sheehy, KK Parker
Advanced drug delivery reviews 96, 83-102, 2016
1532016
Nuclear morphology and deformation in engineered cardiac myocytes and tissues
MAP Bray, WJ Adams, NA Geisse, AW Feinberg, SP Sheehy, KK Parker
Biomaterials 31 (19), 5143-5150, 2010
1292010
JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement
AK Capulli, MY Emmert, FS Pasqualini, D Kehl, E Caliskan, JU Lind, ...
Biomaterials 133, 229-241, 2017
1142017
Structural phenotyping of stem cell-derived cardiomyocytes
FS Pasqualini, SP Sheehy, A Agarwal, Y Aratyn-Schaus, KK Parker
Stem cell reports 4 (3), 340-347, 2015
1132015
Quality metrics for stem cell-derived cardiac myocytes
SP Sheehy, F Pasqualini, A Grosberg, SJ Park, Y Aratyn-Schaus, ...
Stem cell reports 2 (3), 282-294, 2014
1132014
Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip
S Dauth, BM Maoz, SP Sheehy, MA Hemphill, T Murty, MK Macedonia, ...
Journal of neurophysiology 117 (3), 1320-1341, 2017
1112017
The structure–function relationships of a natural nanoscale photonic device in cuttlefish chromatophores
LF Deravi, AP Magyar, SP Sheehy, GRR Bell, LM Mäthger, SL Senft, ...
Journal of The Royal Society Interface 11 (93), 20130942, 2014
1072014
The contribution of cellular mechanotransduction to cardiomyocyte form and function
SP Sheehy, A Grosberg, KK Parker
Biomechanics and modeling in mechanobiology 11, 1227-1239, 2012
1072012
Control of myocyte remodeling in vitro with engineered substrates
NA Geisse, SP Sheehy, KK Parker
In Vitro Cellular & Developmental Biology-Animal 45, 343-350, 2009
1072009
Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model
CO Chantre, PH Campbell, HM Golecki, AT Buganza, AK Capulli, ...
Biomaterials 166, 96-108, 2018
1062018
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip
M Yadid, JU Lind, HAM Ardoña, SP Sheehy, LE Dickinson, F Eweje, ...
Science translational medicine 12 (565), eaax8005, 2020
1042020
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