α-Synuclein promotes SNARE-complex assembly in vivo and in vitro J Burré, M Sharma, T Tsetsenis, V Buchman, MR Etherton, TC Südhof Science 329 (5999), 1663-1667, 2010 | 2233 | 2010 |
Cell biology and pathophysiology of α-synuclein J Burré, M Sharma, TC Südhof Cold Spring Harbor perspectives in medicine 8 (3), a024091, 2018 | 636 | 2018 |
α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation J Burré, M Sharma, TC Südhof Proceedings of the National Academy of Sciences 111 (40), E4274-E4283, 2014 | 580 | 2014 |
The ΔF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR K Du, M Sharma, GL Lukacs Nature structural & molecular biology 12 (1), 17-25, 2005 | 439 | 2005 |
Properties of native brain α-synuclein J Burré, S Vivona, J Diao, M Sharma, AT Brunger, TC Südhof Nature 498 (7453), E4-E6, 2013 | 427 | 2013 |
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2 J Diao, J Burré, S Vivona, DJ Cipriano, M Sharma, M Kyoung, TC Südhof, ... elife 2, e00592, 2013 | 416 | 2013 |
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes M Sharma, F Pampinella, C Nemes, M Benharouga, J So, K Du, ... The Journal of cell biology 164 (6), 923-933, 2004 | 405 | 2004 |
The complexity of tau in Alzheimer’s disease NN Naseri, H Wang, J Guo, M Sharma, W Luo Neuroscience letters 705, 183-194, 2019 | 385 | 2019 |
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function M Etherton, C Földy, M Sharma, K Tabuchi, X Liu, M Shamloo, ... Proceedings of the National Academy of Sciences 108 (33), 13764-13769, 2011 | 381 | 2011 |
CASK Functions as a Mg2+-independent neurexin kinase K Mukherjee, M Sharma, H Urlaub, GP Bourenkov, R Jahn, TC Südhof, ... Cell 133 (2), 328-339, 2008 | 320 | 2008 |
CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity M Sharma, J Burré, TC Südhof Nature cell biology 13 (1), 30-39, 2011 | 299 | 2011 |
Conformational and temperature-sensitive stability defects of the ΔF508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments M Sharma, M Benharouga, W Hu, GL Lukacs Journal of Biological Chemistry 276 (12), 8942-8950, 2001 | 274 | 2001 |
Definition of a molecular pathway mediating α-synuclein neurotoxicity J Burré, M Sharma, TC Südhof Journal of Neuroscience 35 (13), 5221-5232, 2015 | 249 | 2015 |
Systematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activities J Burré, M Sharma, TC Südhof Journal of Neuroscience 32 (43), 15227-15242, 2012 | 217 | 2012 |
CSPα knockout causes neurodegeneration by impairing SNAP‐25 function M Sharma, J Burré, P Bronk, Y Zhang, W Xu, TC Südhof The EMBO journal 31 (4), 829-841, 2012 | 174 | 2012 |
An autism‐associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor‐mediated synaptic transmission in hippocampus MR Etherton, K Tabuchi, M Sharma, J Ko, TC Südhof The EMBO journal 30 (14), 2908-2919, 2011 | 164 | 2011 |
Determinants of the nuclear localization of the heterodimeric DNA fragmentation factor (ICAD/CAD) D Lechardeur, L Drzymala, M Sharma, D Zylka, R Kinach, J Pacia, ... The Journal of cell biology 150 (2), 321-334, 2000 | 122 | 2000 |
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ A Pertsinidis, K Mukherjee, M Sharma, ZP Pang, SR Park, Y Zhang, ... Proceedings of the National Academy of Sciences 110 (30), E2812-E2820, 2013 | 116 | 2013 |
α-Synuclein in synaptic function and dysfunction M Sharma, J Burré Trends in neurosciences 46 (2), 153-166, 2023 | 101 | 2023 |
Proteasome inhibition alleviates SNARE-dependent neurodegeneration M Sharma, J Burré, TC Südhof Science translational medicine 4 (147), 147ra113-147ra113, 2012 | 92 | 2012 |