| Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 560* | 2021 |
| Massively parallel assessment of human variants with base editor screens RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ... Cell 184 (4), 1064-1080. e20, 2021 | 264 | 2021 |
| Optimization of AsCas12a for combinatorial genetic screens in human cells PC DeWeirdt, KR Sanson, AK Sangree, M Hegde, RE Hanna, MN Feeley, ... Nature biotechnology 39 (1), 94-104, 2021 | 169* | 2021 |
| Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei, MM Alfajaro, Q Shi, ... Cell 184 (9), 2394-2411. e16, 2021 | 165 | 2021 |
| Genetic screens in isogenic mammalian cell lines without single cell cloning PC DeWeirdt, AK Sangree, RE Hanna, KR Sanson, M Hegde, C Strand, ... Nature communications 11 (1), 752, 2020 | 110 | 2020 |
| Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses A Rebendenne, P Roy, B Bonaventure, AL Chaves Valadão, L Desmarets, ... bioRxiv, 2021.05. 19.444823, 2021 | 104* | 2021 |
| Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2 AK Sangree, AL Griffith, ZM Szegletes, P Roy, PC DeWeirdt, M Hegde, ... Nature Communications 13 (1), 1318, 2022 | 45 | 2022 |
| Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection J Wei, A Patil, CK Collings, MM Alfajaro, Y Liang, WL Cai, MS Strine, ... Nature Genetics 55 (3), 471-483, 2023 | 27 | 2023 |
| Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells WF Lenoir, M Morgado, PC DeWeirdt, M McLaughlin, AL Griffith, ... Nature communications 12 (1), 6506, 2021 | 25 | 2021 |
| Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening PC DeWeirdt, AV McGee, F Zheng, I Nwolah, M Hegde, JG Doench Nature communications 13 (1), 1-11, 2022 | 21 | 2022 |
| DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner MS Strine, WL Cai, J Wei, MM Alfajaro, RB Filler, SB Biering, S Sarnik, ... PLoS biology 21 (6), e3002097, 2023 | 12 | 2023 |
| Chromatin complex dependencies reveal targeting opportunities in leukemia FJ Najm, P DeWeirdt, MM Moore, SM Bevill, CA El Farran, KA Macias, ... Nature Communications 14 (1), 448, 2023 | 7 | 2023 |
| DefensePredictor: A Machine Learning Model to Discover Novel Prokaryotic Immune Systems PC DeWeirdt, EM Mahoney, MT Laub bioRxiv, 2025.01. 08.631726, 2025 | | 2025 |
| Abstract PR014: Combinatorial genetic screens to map synthetic lethal interactions and identify new cancer drug targets in KRAS mutant cancers R Arafeh, L Chang, L Sawyer, H Wang, J McFarland, J Dempster, ... Molecular Cancer Therapeutics 23 (6_Supplement), PR014-PR014, 2024 | | 2024 |
| Abstract B015: Combinatorial genetic screens to map synthetic lethal interactions and identify new cancer drug targets in KRAS mutant cancers R Arafeh, L Chang, L Sawyer, H Wang, J McFarland, J Dempster, ... Molecular Cancer Therapeutics 23 (6_Supplement), B015-B015, 2024 | | 2024 |
