Spirooxindoles: Promising scaffolds for anticancer agents B Yu, DQ Yu, HM Liu European journal of medicinal chemistry 97, 673-698, 2015 | 840 | 2015 |
Design and synthesis of novel 1, 2, 3-triazole-dithiocarbamate hybrids as potential anticancer agents YC Duan, YC Ma, E Zhang, XJ Shi, MM Wang, XW Ye, HM Liu European journal of medicinal chemistry 62, 11-19, 2013 | 309 | 2013 |
Triazole–dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration YC Zheng, YC Duan, JL Ma, RM Xu, X Zi, WL Lv, MM Wang, XW Ye, ... Journal of medicinal chemistry 56 (21), 8543-8560, 2013 | 247 | 2013 |
Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp) H Zhang, H Xu, CR Ashby Jr, YG Assaraf, ZS Chen, HM Liu Medicinal research reviews 41 (1), 525-555, 2021 | 226 | 2021 |
A systematic review of histone lysine‐specific demethylase 1 and its inhibitors YC Zheng, J Ma, Z Wang, J Li, B Jiang, W Zhou, X Shi, X Wang, W Zhao, ... Medicinal research reviews 35 (5), 1032-1071, 2015 | 221 | 2015 |
Isolation and structure elucidation of gymnemic acids, antisweet principles of Gymnema sylvestre HM LIU, F Kiuchi, Y Tsuda Chemical and Pharmaceutical Bulletin 40 (6), 1366-1375, 1992 | 184 | 1992 |
Design, synthesis, and structure–activity relationship of novel LSD1 inhibitors based on pyrimidine–thiourea hybrids as potent, orally active antitumor agents LY Ma, YC Zheng, SQ Wang, B Wang, ZR Wang, LP Pang, M Zhang, ... Journal of medicinal chemistry 58 (4), 1705-1716, 2015 | 175 | 2015 |
Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: Success and challenges B Yu, Z Yu, PP Qi, DQ Yu, HM Liu European Journal of Medicinal Chemistry 95, 35-40, 2015 | 167 | 2015 |
Targeting Brd4 for cancer therapy: inhibitors and degraders Y Duan, Y Guan, W Qin, X Zhai, B Yu, H Liu Medchemcomm 9 (11), 1779-1802, 2018 | 150 | 2018 |
Synthesis and biological evaluation of novel steroidal [17, 16-d][1, 2, 4] triazolo [1, 5-a] pyrimidines LH Huang, YF Zheng, YZ Lu, CJ Song, YG Wang, B Yu, HM Liu Steroids 77 (6), 710-715, 2012 | 134 | 2012 |
Natural product-derived spirooxindole fragments serve as privileged substructures for discovery of new anticancer agents B Yu, YC Zheng, XJ Shi, PP Qi, HM Liu Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2016 | 127 | 2016 |
Design, synthesis and antiproliferative activity studies of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids YC Duan, YC Zheng, XC Li, MM Wang, XW Ye, YY Guan, GZ Liu, ... European journal of medicinal chemistry 64, 99-110, 2013 | 127 | 2013 |
USP7: novel drug target in cancer therapy Z Wang, W Kang, Y You, J Pang, H Ren, Z Suo, H Liu, Y Zheng Frontiers in Pharmacology 10, 427, 2019 | 125 | 2019 |
p‐Coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii T Akiyama, M Shibuya, HM Liu, Y Ebizuka European journal of biochemistry 263 (3), 834-839, 1999 | 120 | 1999 |
Design and synthesis of novel 1, 2, 3-triazole-pyrimidine hybrids as potential anticancer agents LY Ma, LP Pang, B Wang, M Zhang, B Hu, DQ Xue, KP Shao, BL Zhang, ... European journal of medicinal chemistry 86, 368-380, 2014 | 118 | 2014 |
High incidence and endemic spread of NDM-1-positive Enterobacteriaceae in Henan Province, China S Qin, Y Fu, Q Zhang, H Qi, JG Wen, H Xu, L Xu, L Zeng, H Tian, L Rong, ... Antimicrobial agents and chemotherapy 58 (8), 4275-4282, 2014 | 116 | 2014 |
Skp2 in the ubiquitin‐proteasome system: a comprehensive review MD Asmamaw, Y Liu, YC Zheng, XJ Shi, HM Liu Medicinal Research Reviews 40 (5), 1920-1949, 2020 | 114 | 2020 |
Design and synthesis of novel 1, 2, 3-triazole–pyrimidine–urea hybrids as potential anticancer agents LY Ma, B Wang, LP Pang, M Zhang, SQ Wang, YC Zheng, KP Shao, ... Bioorganic & Medicinal Chemistry Letters 25 (5), 1124-1128, 2015 | 114 | 2015 |
LSD1 deletion decreases exosomal PD-L1 and restores T-cell response in gastric cancer DD Shen, JR Pang, YP Bi, LF Zhao, YR Li, LJ Zhao, Y Gao, B Wang, ... Molecular cancer 21 (1), 75, 2022 | 109 | 2022 |
A review of progress in histone deacetylase 6 inhibitors research: structural specificity and functional diversity XH Zhang, Qin-Ma, HP Wu, MY Khamis, YH Li, LY Ma, HM Liu Journal of medicinal chemistry 64 (3), 1362-1391, 2021 | 106 | 2021 |