| Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells X Ye, B Zerlanko, A Kennedy, G Banumathy, R Zhang, PD Adams Molecular cell 27 (2), 183-196, 2007 | 253 | 2007 |
| Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis AL Kennedy, JP Morton, I Manoharan, DM Nelson, NB Jamieson, ... Molecular cell 42 (1), 36-49, 2011 | 237 | 2011 |
| Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias CG Mullighan, A Kennedy, X Zhou, I Radtke, LA Phillips, SA Shurtleff, ... Leukemia 21 (9), 2000-2009, 2007 | 224 | 2007 |
| Genetic predisposition to MDS: clinical features and clonal evolution AL Kennedy, A Shimamura Blood, The Journal of the American Society of Hematology 133 (10), 1071-1085, 2019 | 146 | 2019 |
| Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome AL Kennedy, KC Myers, J Bowman, CJ Gibson, ND Camarda, E Furutani, ... Nature Communications 12 (1), 1334, 2021 | 134 | 2021 |
| Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma AL Kennedy, M Vallurupalli, L Chen, B Crompton, G Cowley, F Vazquez, ... Oncotarget 6 (30), 30178, 2015 | 98 | 2015 |
| Senescent mouse cells fail to overtly regulate the HIRA histone chaperone and do not form robust Senescence Associated Heterochromatin Foci AL Kennedy, T McBryan, GH Enders, FB Johnson, R Zhang, PD Adams Cell division 5, 1-11, 2010 | 75 | 2010 |
| Pediatric CNS-isolated hemophagocytic lymphohistiocytosis LA Benson, H Li, LA Henderson, IH Solomon, A Soldatos, J Murphy, ... Neurology: Neuroimmunology & Neuroinflammation 6 (3), e560, 2019 | 68 | 2019 |
| Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1 PC Scacheri, JS Crabtree, AL Kennedy, GP Swain, JM Ward, SJ Marx, ... Mammalian Genome 15, 872-877, 2004 | 67 | 2004 |
| Pediatric NUT-midline carcinoma: Therapeutic success employing a sarcoma based multimodal approach S Storck, AL Kennedy, KJ Marcus, L Teot, J Vaughn, AK Gnekow, B Märkl, ... Pediatric hematology and oncology 34 (4), 231-237, 2017 | 63 | 2017 |
| Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy AL Kennedy, PD Adams, JP Morton Small GTPases 2 (5), 36-49, 2011 | 39 | 2011 |
| Dissecting ELANE neutropenia pathogenicity by human HSC gene editing S Rao, Y Yao, JS de Brito, Q Yao, AH Shen, RE Watkinson, AL Kennedy, ... Cell Stem Cell 28 (5), 833-845. e5, 2021 | 38 | 2021 |
| Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability PC Scacheri, AL Kennedy, K Chin, MT Miller, JG Hodgson, JW Gray, ... Cancer research 64 (19), 7039-7044, 2004 | 27 | 2004 |
| Central nervous system–restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation H Li, LA Benson, LA Henderson, IH Solomon, AL Kennedy, A Soldatos, ... Blood Advances 3 (4), 503-507, 2019 | 17 | 2019 |
| The frequent and clinically benign anomalies of chromosomes 7 and 20 in Shwachman-diamond syndrome may be subject to further clonal variations AW Khan, A Kennedy, E Furutani, K Myers, A Frattini, F Acquati, P Roccia, ... Molecular Cytogenetics 14, 1-9, 2021 | 12 | 2021 |
| V804M RET mutation in MEN 2A: first report PC Scacheri, JS Crabtree, AL Kennedy, GP Swain, JM Ward, SJ Marx, ... JOURNAL OF INTERNAL MEDICINE 255 (6), 712-712, 2004 | 8 | 2004 |
| Targeting EZH2 for the treatment of hepatosplenic T-cell lymphoma Y Pikman, AS Conway, AL Robichaud, S Kitara, AJ Church, AL Kennedy, ... Blood Advances 4 (7), 1265-1269, 2020 | 7 | 2020 |
| Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma. Oncotarget. 2015; 6: 30178–93 AL Kennedy, M Vallurupalli, L Chen, B Crompton, G Cowley, F Vazquez, ... PubMed Abstract| Publisher Full Text| Free Full Text, 0 | 7 | |
| Pediatric Acute Myeloid Leukemia with Nucleophosmin Mutations Is Characterized by a Gene Expression Signature with Dysregulated HOX Gene Expression Distinct from … CG Mullighan, AL Kennedy, X Zhou, SA Shurtleff, JR Downing Blood, The Journal of the American Society of Hematology 106 (11), 2993-2993, 2005 | 5 | 2005 |
| Large genomic deletions in Shwachman-Diamond syndrome LJ McReynolds, K Jones, K Teshome, A Kennedy, A Shimamura, N Giri, ... Blood 132, 2586, 2018 | 2 | 2018 |
