Gasdermin E suppresses tumour growth by activating anti-tumour immunity Z Zhang, Y Zhang, S Xia, Q Kong, S Li, X Liu, C Junqueira, KF Meza-Sosa, ... Nature 579 (7799), 415-420, 2020 | 1271 | 2020 |
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ... Nature immunology 21 (7), 736-745, 2020 | 803 | 2020 |
Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy Y Zhang, R Kurupati, L Liu, XY Zhou, G Zhang, A Hudaihed, F Filisio, ... Cancer Cell 32 (3), 377-391. e9, 2017 | 539 | 2017 |
Starved and asphyxiated: how can CD8+ T cells within a tumor microenvironment prevent tumor progression Y Zhang, HCJ Ertl Frontiers in immunology 7, 32, 2016 | 115 | 2016 |
Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+ T cells within tumors Y Zhang, HCJ Ertl Oncotarget 7 (17), 23282, 2016 | 106 | 2016 |
Targeting stem-loop 1 of the SARS-CoV-2 5′ UTR to suppress viral translation and Nsp1 evasion SM Vora, P Fontana, T Mao, V Leger, Y Zhang, TM Fu, J Lieberman, ... Proceedings of the National Academy of Sciences 119 (9), e2117198119, 2022 | 94 | 2022 |
The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells S Sen Santara, DJ Lee, Â Crespo, JJ Hu, C Walker, X Ma, Y Zhang, ... Nature 616 (7956), 348-356, 2023 | 88 | 2023 |
Lighting a Fire: Can We Harness Pyroptosis to Ignite Antitumor Immunity? Z Zhang, Y Zhang, J Lieberman Cancer immunology research 9 (1), 2-7, 2021 | 87 | 2021 |
SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism M Shi, L Wang, P Fontana, S Vora, Y Zhang, TM Fu, J Lieberman, H Wu BioRxiv, 2020 | 74 | 2020 |
TGF-β-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38 MAPK, MAP2K4 and MAP2K7 S Min, L Li, M Zhang, Y Zhang, X Liang, Y Xie, Q He, Y Li, J Sun, Q Liu, ... Genes & Immunity 13 (8), 621-631, 2012 | 71 | 2012 |
Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown Y Zhang, X Xie, PN Yeganeh, DJ Lee, D Valle-Garcia, KF Meza-Sosa, ... Proceedings of the National Academy of Sciences 118 (9), 2021 | 62 | 2021 |
Antigen presentation by dendritic cells in tumors is disrupted by altered metabolism that involves pyruvate kinase M2 and its interaction with SOCS3 Z Zhang, Q Liu, Y Che, X Yuan, L Dai, B Zeng, G Jiao, Y Zhang, X Wu, ... Cancer research 70 (1), 89-98, 2010 | 52 | 2010 |
SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage KF Meza-Sosa, R Miao, F Navarro, Z Zhang, Y Zhang, JJ Hu, ... Molecular Cell 82 (4), 785-802. e10, 2022 | 35 | 2022 |
The effect of adjuvanting cancer vaccines with herpes simplex virus glycoprotein D on melanoma-driven CD8+ T cell exhaustion Y Zhang, HCJ Ertl The Journal of Immunology 193 (4), 1836-1846, 2014 | 29 | 2014 |
Methods and compositions for treating cancer HCJ Ertl, Y Zhang US Patent 9,402,888, 2016 | 15 | 2016 |
Small-molecule GSDMD agonism in tumors stimulates antitumor immunity without toxicity P Fontana, G Du, Y Zhang, H Zhang, SM Vora, JJ Hu, M Shi, AB Tufan, ... Cell, 2024 | 10 | 2024 |
The Relationship between Internet Addiction and Internalizing Problems in Overweight/Obese Adolescents: A Moderated Mediation Model Z Wei, Z Zheng, Y Zhang, R Song, J Zhu, G Wan, Z Peng The North American Journal of Medicine and Science 10 (4), 139-147, 2017 | 7 | 2017 |
Aging: T cell metabolism within tumors Y Zhang, HCJ Ertl Aging (Albany NY) 8 (6), 1163, 2016 | 6 | 2016 |
Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation Y Zhang, P Naderi Yeganeh, H Zhang, SY Wang, Z Li, B Gu, DJ Lee, ... Nature Immunology, 1-13, 2024 | 5 | 2024 |
T and B Cell Metabolism in Older Adults Y Zhang, HCJ Ertl Immunometabolism 2 (3), 2020 | 2 | 2020 |