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Saori Sakaue
Saori Sakaue
Harvard Medical School
Adresse e-mail validée de broadinstitute.org - Page d'accueil
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
Nature genetics 50 (4), 524-537, 2018
14622018
A cross-population atlas of genetic associations for 220 human phenotypes
S Sakaue, M Kanai, Y Tanigawa, J Karjalainen, M Kurki, S Koshiba, ...
Nature genetics 53 (10), 1415-1424, 2021
13452021
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
6232021
The polygenic and monogenic basis of blood traits and diseases
D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ...
Cell 182 (5), 1214-1231. e11, 2020
5572020
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
5452022
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations
MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ...
Cell 182 (5), 1198-1213. e14, 2020
5162020
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
K Ishigaki, M Akiyama, M Kanai, A Takahashi, E Kawakami, H Sugishita, ...
Nature genetics 52 (7), 669-679, 2020
4402020
Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data
D Shungin, S Haworth, K Divaris, CS Agler, Y Kamatani, M Keun Lee, ...
Nature communications 10 (1), 2773, 2019
2742019
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis
K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara, K Yamaguchi, ...
Nature genetics 54 (11), 1640-1651, 2022
2052022
Characterizing rare and low-frequency height-associated variants in the Japanese population
M Akiyama, K Ishigaki, S Sakaue, Y Momozawa, M Horikoshi, M Hirata, ...
Nature communications 10 (1), 4393, 2019
1732019
Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese
Y Okada, Y Momozawa, S Sakaue, M Kanai, K Ishigaki, M Akiyama, ...
Nature communications 9 (1), 1631, 2018
1642018
Cerebral small vessel disease genomics and its implications across the lifespan
M Sargurupremraj, H Suzuki, X Jian, C Sarnowski, TE Evans, JC Bis, ...
Nature communications 11 (1), 6285, 2020
1502020
A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response
Y Luo, M Kanai, W Choi, X Li, S Sakaue, K Yamamoto, K Ogawa, ...
Nature genetics 53 (10), 1504-1516, 2021
1372021
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium
R Malik, G Chauhan, M Traylor, M Sargurupremraj, Y Okada, A Mishra, ...
International Genomics of Blood Pressure (iGEN-BP) Consortium, 524-537, 2018
1372018
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data
MJ Zhang, K Hou, KK Dey, S Sakaue, KA Jagadeesh, K Weinand, ...
Nature genetics 54 (10), 1572-1580, 2022
1092022
Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan
S Sakaue, M Kanai, J Karjalainen, M Akiyama, M Kurki, N Matoba, ...
Nature medicine 26 (4), 542-548, 2020
1052020
Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population
J Hirata, K Hosomichi, S Sakaue, M Kanai, H Nakaoka, K Ishigaki, ...
Nature genetics 51 (3), 470-480, 2019
962019
Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction
S Sakaue, J Hirata, M Kanai, K Suzuki, M Akiyama, C Lai Too, T Arayssi, ...
Nature communications 11 (1), 1569, 2020
852020
Insights from complex trait fine-mapping across diverse populations
M Kanai, JC Ulirsch, J Karjalainen, M Kurki, KJ Karczewski, E Fauman, ...
medrxiv, 2021.09. 03.21262975, 2021
722021
Transethnic meta-analysis of genome-wide association studies identifies three new loci and characterizes population-specific differences for coronary artery disease
H Matsunaga, K Ito, M Akiyama, A Takahashi, S Koyama, S Nomura, ...
Circulation: Genomic and Precision Medicine 13 (3), e002670, 2020
722020
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