| Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19 ED Hottz, IG Azevedo-Quintanilha, L Palhinha, L Teixeira, EA Barreto, ... Blood, The Journal of the American Society of Hematology 136 (11), 1330-1341, 2020 | 778 | 2020 |
| Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation ED Hottz, JF Lopes, C Freitas, R Valls-de-Souza, MF Oliveira, MT Bozza, ... Blood, The Journal of the American Society of Hematology 122 (20), 3405-3414, 2013 | 384 | 2013 |
| SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes AC Ferreira, VC Soares, IG de Azevedo-Quintanilha, SSG Dias, ... Cell death discovery 7 (1), 43, 2021 | 282 | 2021 |
| Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators SSG Dias, VC Soares, AC Ferreira, CQ Sacramento, ... PLoS pathogens 16 (12), e1009127, 2020 | 271 | 2020 |
| Dengue induces platelet activation, mitochondrial dysfunction and cell death through mechanisms that involve DC-SIGN and caspases ED Hottz, MF Oliveira, PCG Nunes, RMR Nogueira, R Valls-de-Souza, ... Journal of Thrombosis and Haemostasis 11 (5), 951-962, 2013 | 237 | 2013 |
| Platelets in immune response to virus and immunopathology of viral infections ED Hottz, FA Bozza, PT Bozza Frontiers in medicine 5, 121, 2018 | 228 | 2018 |
| Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue ED Hottz, IM Medeiros-de-Moraes, A Vieira-de-Abreu, EF de Assis, ... The Journal of Immunology 193 (4), 1864-1872, 2014 | 200 | 2014 |
| Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3 RA Campbell, H Schwertz, ED Hottz, JW Rowley, BK Manne, ... Blood, The Journal of the American Society of Hematology 133 (19), 2013-2026, 2019 | 175 | 2019 |
| Innate immune receptors in platelets and platelet-leukocyte interactions PRB Dib, AC Quirino-Teixeira, LB Merij, MBM Pinheiro, SV Rozini, ... Journal of Leucocyte Biology 108 (4), 1157-1182, 2020 | 169 | 2020 |
| Platelets in dengue infection E Hottz, ND Tolley, GA Zimmerman, AS Weyrich, FA Bozza Drug Discovery Today: Disease Mechanisms 8 (1-2), e33-e38, 2011 | 121 | 2011 |
| Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue MRO Trugilho, ED Hottz, GVF Brunoro, A Teixeira-Ferreira, PC Carvalho, ... PLoS pathogens 13 (5), e1006385, 2017 | 117 | 2017 |
| Leptin induces proadipogenic and proinflammatory signaling in adipocytes L Palhinha, S Liechocki, ED Hottz, JAS Pereira, CJ de Almeida, ... Frontiers in endocrinology 10, 841, 2019 | 107 | 2019 |
| Breast-cancer extracellular vesicles induce platelet activation and aggregation by tissue factor-independent and-dependent mechanisms FG Gomes, V Sandim, VH Almeida, AMR Rondon, BB Succar, ED Hottz, ... Thrombosis research 159, 24-32, 2017 | 89 | 2017 |
| Persistent platelet activation and apoptosis in virologically suppressed HIV-infected individuals EC Mesquita, ED Hottz, RT Amancio, AB Carneiro, L Palhinha, LE Coelho, ... Scientific reports 8 (1), 14999, 2018 | 69 | 2018 |
| Inflammasome in platelets: allying coagulation and inflammation in infectious and sterile diseases? ED Hottz, APT Monteiro, FA Bozza, PT Bozza Mediators of inflammation 2015 (1), 435783, 2015 | 62 | 2015 |
| Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19 ED Hottz, R Martins-Gonçalves, L Palhinha, IG Azevedo-Quintanilha, ... Blood Advances 6 (17), 5085-5099, 2022 | 54 | 2022 |
| Emerging concepts in dengue pathogenesis: interplay between plasmablasts, platelets, and complement in triggering vasculopathy EJM Nascimento, ED Hottz, TM Garcia-Bates, F Bozza, ETA Marques Jr, ... Critical Reviews™ in Immunology 34 (3), 2014 | 53 | 2014 |
| Simvastatin downregulates the SARS-CoV-2-induced inflammatory response and impairs viral infection through disruption of lipid rafts L Teixeira, JR Temerozo, FS Pereira-Dutra, AC Ferreira, M Mattos, ... Frontiers in Immunology 13, 820131, 2022 | 46 | 2022 |
| Inflammatory signaling in dengue-infected platelets requires translation and secretion of nonstructural protein 1 AC Quirino-Teixeira, SV Rozini, G Barbosa-Lima, DR Coelho, ... Blood advances 4 (9), 2018-2031, 2020 | 44 | 2020 |
| Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway MBF Werneck, E Hottz, PT Bozza, JPB Viola Cell cycle 11 (21), 3997-4008, 2012 | 43 | 2012 |
Patricia T BozzaInstituto Oswaldo Cruz, FIOCRUZAdresse e-mail validée de ioc.fiocruz.br