The transcriptional activator Gli2 modulates T-cell receptor signalling through attenuation of AP-1 and NFκB activity AL Furmanski, A Barbarulo, A Solanki, CI Lau, H Sahni, JI Saldana, ... Journal of Cell Science 128 (11), 2085-2095, 2015 | 56 | 2015 |
Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation E Papaioannou, DC Yánez, S Ross, CI Lau, A Solanki, MM Chawda, ... The Journal of Clinical Investigation 129 (8), 3153-3170, 2019 | 53 | 2019 |
IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation DC Yánez, H Sahni, S Ross, A Solanki, CI Lau, E Papaioannou, ... European journal of immunology 49 (1), 66-78, 2019 | 52 | 2019 |
Regulation of murine normal and stress-induced erythropoiesis by Desert Hedgehog C Lau, SV Outram, J Ignacio Saldaña, AL Furmanski, JT Dessens, ... Blood, The Journal of the American Society of Hematology 119 (20), 4741-4751, 2012 | 49 | 2012 |
Sonic Hedgehog regulates thymic epithelial cell differentiation JI Saldana, A Solanki, CI Lau, H Sahni, S Ross, AL Furmanski, M Ono, ... Journal of Autoimmunity 68, 86-97, 2016 | 45 | 2016 |
Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of Shh A Solanki, DC Yanez, S Ross, CI Lau, E Papaioannou, J Li, JI Saldaña, ... Development 145 (3), dev146910, 2018 | 37 | 2018 |
The transcriptional repressor Bcl6 promotes pre-TCR-induced thymocyte differentiation and attenuates Notch1 activation A Solanki, DC Yánez, CI Lau, J Rowell, A Barbarulo, S Ross, H Sahni, ... Development 147 (19), dev192203, 2020 | 29 | 2020 |
The transcription factor Gli3 promotes B cell development in fetal liver through repression of Shh A Solanki, CI Lau, JI Saldaña, S Ross, T Crompton Journal of Experimental Medicine 214 (7), 2041-2058, 2017 | 29 | 2017 |
A genome wide transcriptional model of the complex response to pre-TCR signalling during thymocyte differentiation H Sahni, S Ross, A Barbarulo, A Solanki, CI Lau, A Furmanski, JI Saldaña, ... Oncotarget 6 (30), 28646, 2015 | 25 | 2015 |
Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation CI Lau, DC Yánez, E Papaioannou, S Ross, T Crompton The FEBS journal 289 (24), 8050-8061, 2022 | 24 | 2022 |
Hedgehog signaling promotes TH2 differentiation in naive human CD4 T cells DC Yánez, CI Lau, MM Chawda, S Ross, AL Furmanski, T Crompton Journal of Allergy and Clinical Immunology 144 (5), 1419-1423. e1, 2019 | 24 | 2019 |
The kinesin motor protein Kif7 is required for T-cell development and normal MHC expression on thymic epithelial cells (TEC) in the thymus CI Lau, A Barbarulo, A Solanki, JI Saldaña, T Crompton Oncotarget 8 (15), 24163, 2017 | 24 | 2017 |
Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation CI Lau, DC Yánez, A Solanki, E Papaioannou, JI Saldaña, T Crompton Journal of autoimmunity 93, 131-138, 2018 | 21 | 2018 |
Hedgehog signalling in the embryonic mouse thymus A Barbarulo, CI Lau, K Mengrelis, S Ross, A Solanki, JI Saldaña, ... Journal of developmental biology 4 (3), 22, 2016 | 20 | 2016 |
The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection CI Lau, J Rowell, DC Yanez, A Solanki, S Ross, M Ono, T Crompton Development 148 (15), dev199754, 2021 | 17 | 2021 |
Sonic hedgehog is a determinant of γδ T-cell differentiation in the thymus K Mengrelis, CI Lau, J Rowell, A Solanki, S Norris, S Ross, M Ono, ... Frontiers in Immunology 10, 1629, 2019 | 17 | 2019 |
Systemic pharmacological smoothened inhibition reduces lung T-cell infiltration and ameliorates Th2 inflammation in a mouse model of allergic airway disease DC Yánez, E Papaioannou, MM Chawda, J Rowell, S Ross, CI Lau, ... Frontiers in Immunology 12, 737245, 2021 | 16 | 2021 |
Dysregulated gene expression in oocysts of Plasmodium berghei LAP mutants S Saeed, CI Lau, AZ Tremp, T Crompton, JT Dessens Molecular and biochemical parasitology 229, 1-5, 2019 | 12 | 2019 |
Transplanted human thymus slices induce and support T‐cell development in mice after cryopreservation S Ross, M Cheung, CI Lau, N Sebire, M Burch, P Kilbride, B Fuller, ... European journal of immunology, 2018 | 11 | 2018 |
T cell phenotype in paediatric heart transplant recipients K Mengrelis, F Kucera, N Shahid, E Watt, S Ross, CI Lau, S Adams, ... Pediatric Transplantation 25 (5), e13930, 2021 | 7 | 2021 |