‪H Eric Xu (徐华强), Professor‬

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237 articles

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Karsten MelcherVan Andel InstituteAdresse e-mail validée de vai.org
Millard H LambertComputational Chemist, GlaxoSmithKlineAdresse e-mail validée de gsk.com
Wanchao YinShanghai Institute of Materia MedicaAdresse e-mail validée de simm.ac.cn
Yan ZhangZhejiang University School of MedicineAdresse e-mail validée de zju.edu.cn
Yuanzheng HeHarbin Institute of TechnologyAdresse e-mail validée de hit.edu.cn
Steven KliewerProfessorAdresse e-mail validée de utsouthwestern.edu
Tim WillsonProfessor, UNC Eshelman School of Pharmacy, UNC Chapel HillAdresse e-mail validée de unc.edu
Wei Yi 易伟Key Laboratory of Molecular Target and Clinical Pharmacology & State Key Laboratory of RespiratoryAdresse e-mail validée de simm.ac.cn
Ming-Wei WangChinese Academy of Sciences/Fudan UniversityAdresse e-mail validée de simm.ac.cn
Parker W de WaalD. E. Shaw ResearchAdresse e-mail validée de DEShawResearch.com
Eu Leong YONGProfessor of Obstetrics and Gynecology, National University of SingaporeAdresse e-mail validée de nus.edu.sg
Yanyong KangBristol Myers SquibbAdresse e-mail validée de bms.com
Jian-Kang ZhuSouthern University of Science and TechnologyAdresse e-mail validée de sustech.edu.cn
Patrick R GriffinProfessor of Molecular Medicine, UF Scripps Biomedical ResearchAdresse e-mail validée de scripps.edu
Xin GuNovartis Gene TherapiesAdresse e-mail validée de novartis.com
Yanting YinJanssen-Pharmaceutical company of Johnson & JohnsonAdresse e-mail validée de vai.org
Eileen Tan Mei HuiNational University of SingaporeAdresse e-mail validée de nus.edu.sg
Ng Ley MoyNational University of SingaporeAdresse e-mail validée de nus.edu.sg
BL RothDepartment of Pharmacology, University of North Carolina Medical SchoolAdresse e-mail validée de med.unc.edu
XP HuangUniversity of North CarolinaAdresse e-mail validée de unc.edu

Suivre

H Eric Xu (徐华强), Professor

Shanghai Institute of Materia Medica, CAS; Tsinghua; Duke; UTSW; MIT; VARI/GlaxoWellcome/GSK

Adresse e-mail validée de simm.ac.cn

drug design GPCR nuclear hormone receptors structural biology


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Amyloid beta: structure, biology and structure-based therapeutic development G Chen, T Xu, Y Yan, Y Zhou, Y Jiang, K Melcher, HE Xu Acta pharmacologica sinica 38 (9), 1205-1235, 2017	2026	2017
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ... Molecular cell 3 (3), 397-403, 1999	1528	1999
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ... Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001	1473	2001
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir W Yin, C Mao, X Luan, DD Shen, Q Shen, H Su, X Wang, F Zhou, W Zhao, ... Science 368 (6498), 1499-1504, 2020	1280	2020
Androgen receptor: structure, role in prostate cancer and drug discovery MH Tan, J Li, HE Xu, K Melcher, E Yong Acta Pharmacologica Sinica 36 (1), 3-23, 2015	1108	2015
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ... Cell 110 (1), 93-105, 2002	1014	2002
DWARF 53 acts as a repressor of strigolactone signalling in rice L Jiang, X Liu, G Xiong, H Liu, F Chen, L Wang, X Meng, G Liu, H Yu, ... Nature 504 (7480), 401-405, 2013	874	2013
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ... Nature 523 (7562), 561-567, 2015	871	2015
Structural features for functional selectivity at serotonin receptors D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ... Science 340 (6132), 615-619, 2013	823	2013
A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors K Melcher, LM Ng, XE Zhou, FF Soon, Y Xu, KM Suino-Powell, SY Park, ... Nature 462 (7273), 602-608, 2009	801	2009
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ... Nature 415 (6873), 813-817, 2002	777	2002
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors RT Gampe, VG Montana, MH Lambert, AB Miller, RK Bledsoe, MV Milburn, ... Molecular cell 5 (3), 545-555, 2000	756	2000
Structural basis for molecular recognition of folic acid by folate receptors C Chen, J Ke, XE Zhou, W Yi, JS Brunzelle, J Li, EL Yong, HE Xu, ... Nature 500 (7463), 486-489, 2013	752	2013
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ... Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001	688	2001
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ... Science 331 (6024), 1621-1624, 2011	686	2011
Identification of a physiologically relevant endogenous ligand for PPARα in liver MV Chakravarthy, IJ Lodhi, L Yin, RRV Malapaka, HE Xu, J Turk, ... Cell 138 (3), 476-488, 2009	657	2009
Structural basis for molecular recognition at serotonin receptors C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ... Science 340 (6132), 610-614, 2013	619	2013
Digoxin and its derivatives suppress T_H17 cell differentiation by antagonizing RORγt activity JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ... Nature 472 (7344), 486-490, 2011	612	2011
Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases FF Soon, LM Ng, XE Zhou, GM West, A Kovach, MHE Tan, ... Science 335 (6064), 85-88, 2012	581	2012
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans DL Motola, CL Cummins, V Rottiers, KK Sharma, T Li, Y Li, ... Cell 124 (6), 1209-1223, 2006	569	2006

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