Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers VS Mandala, MJ McKay, AA Shcherbakov, AJ Dregni, A Kolocouris, ... Nature structural & molecular biology 27 (12), 1202-1208, 2020 | 427 | 2020 |
In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments AJ Dregni, VS Mandala, H Wu, MR Elkins, HK Wang, I Hung, ... Proceedings of the National Academy of Sciences 116 (33), 16357-16366, 2019 | 92 | 2019 |
Chemokines and galectins form heterodimers to modulate inflammation V Eckardt, MC Miller, X Blanchet, R Duan, J Leberzammer, J Duchene, ... EMBO reports 21 (4), e47852, 2020 | 87 | 2020 |
The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations MD Gelenter, KJ Smith, SY Liao, VS Mandala, AJ Dregni, MS Lamm, ... Nature structural & molecular biology 26 (7), 592-598, 2019 | 77 | 2019 |
Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles AJ Dregni, P Duan, H Xu, L Changolkar, N El Mammeri, VMY Lee, ... Nature communications 13 (1), 2967, 2022 | 55 | 2022 |
Inclusion of the C-terminal domain in the β-sheet core of heparin-fibrillized three-repeat tau protein revealed by solid-state nuclear magnetic resonance spectroscopy AJ Dregni, HK Wang, H Wu, P Duan, J Jin, WF DeGrado, M Hong Journal of the American Chemical Society 143 (20), 7839-7851, 2021 | 42 | 2021 |
Microtubule-binding core of the tau protein N El Mammeri, AJ Dregni, P Duan, HK Wang, M Hong Science Advances 8 (29), eabo4459, 2022 | 41 | 2022 |
Hydration and dynamics of full-length tau amyloid fibrils investigated by solid-state nuclear magnetic resonance AJ Dregni, P Duan, M Hong Biochemistry 59 (24), 2237-2248, 2020 | 36 | 2020 |
pH-and calcium-dependent aromatic network in the SARS-CoV-2 envelope protein J Medeiros-Silva, NH Somberg, HK Wang, MJ McKay, VS Mandala, ... Journal of the American Chemical Society 144 (15), 6839-6850, 2022 | 34 | 2022 |
Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β-Amyloid Fibrils Studied Using 19F Solid-State NMR P Duan, KJ Chen, G Wijegunawardena, AJ Dregni, HK Wang, H Wu, ... Journal of the American Chemical Society 144 (3), 1416-1430, 2022 | 33 | 2022 |
Water orientation and dynamics in the closed and open influenza B virus M2 proton channels MD Gelenter, VS Mandala, MJM Niesen, DA Sharon, AJ Dregni, ... Communications Biology 4 (1), 338, 2021 | 30 | 2021 |
SARS-CoV-2 envelope protein forms clustered pentamers in lipid bilayers NH Somberg, WW Wu, J Medeiros-Silva, AJ Dregni, H Jo, WF DeGrado, ... Biochemistry 61 (21), 2280-2294, 2022 | 27 | 2022 |
High-pH structure of EmrE reveals the mechanism of proton-coupled substrate transport AA Shcherbakov, PJ Spreacker, AJ Dregni, KA Henzler-Wildman, M Hong Nature Communications 13 (1), 991, 2022 | 21 | 2022 |
Atomic structure of the open SARS-CoV-2 E viroporin J Medeiros-Silva, AJ Dregni, NH Somberg, P Duan, M Hong Science Advances 9 (41), eadi9007, 2023 | 20 | 2023 |
Amyloid fibril structures of tau: Conformational plasticity of the second microtubule-binding repeat N El Mammeri, P Duan, AJ Dregni, M Hong Science advances 9 (28), eadh4731, 2023 | 15 | 2023 |
Structure of the nonhelical filament of the Alzheimer’s disease tau core P Duan, AJ Dregni, NE Mammeri, M Hong Proceedings of the National Academy of Sciences 120 (44), e2310067120, 2023 | 14 | 2023 |
Pulsed Third-Spin-Assisted Recoupling NMR for Obtaining Long-Range 13C–13C and 15N–13C Distance Restraints MD Gelenter, AJ Dregni, M Hong The Journal of Physical Chemistry B 124 (33), 7138-7151, 2020 | 14 | 2020 |
The cytoplasmic domain of the SARS-CoV-2 envelope protein assembles into a β-sheet bundle in lipid bilayers AJ Dregni, MJ McKay, W Surya, M Queralt-Martin, J Medeiros-Silva, ... Journal of Molecular Biology 435 (5), 167966, 2023 | 12 | 2023 |
Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function MC Miller, IV Nesmelova, VA Daragan, H Ippel, M Michalak, A Dregni, ... Biochemical Journal 477 (17), 3147-3165, 2020 | 12 | 2020 |
Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation NE Mammeri, AJ Dregni, P Duan, M Hong Proceedings of the National Academy of Sciences 121 (10), e2316175121, 2024 | 10 | 2024 |