NF-κB, inflammation, immunity and cancer: coming of age K Taniguchi, M Karin Nature Reviews Immunology 18 (5), 309-324, 2018 | 2539 | 2018 |
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth SI Grivennikov, K Wang, D Mucida, CA Stewart, B Schnabl, D Jauch, ... Nature 491 (7423), 254-258, 2012 | 1445 | 2012 |
IL-6 and related cytokines as the critical lynchpins between inflammation and cancer K Taniguchi, M Karin Seminars in immunology 26 (1), 54-74, 2014 | 824 | 2014 |
A gp130–Src–YAP module links inflammation to epithelial regeneration K Taniguchi, LW Wu, SI Grivennikov, PR De Jong, I Lian, FX Yu, K Wang, ... Nature 519 (7541), 57-62, 2015 | 655 | 2015 |
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development H Nakagawa, A Umemura, K Taniguchi, J Font-Burgada, D Dhar, H Ogata, ... Cancer cell 26 (3), 331-343, 2014 | 541 | 2014 |
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype H Brems, M Chmara, M Sahbatou, E Denayer, K Taniguchi, R Kato, ... Nature genetics 39 (9), 1120-1126, 2007 | 541 | 2007 |
Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer J Font-Burgada, S Shalapour, S Ramaswamy, B Hsueh, D Rossell, ... Cell 162 (4), 766-779, 2015 | 494 | 2015 |
p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 456 | 2016 |
Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma S Finkin, D Yuan, I Stein, K Taniguchi, A Weber, K Unger, JL Browning, ... Nature immunology 16 (12), 1235-1244, 2015 | 385 | 2015 |
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis K Wang, MK Kim, G Di Caro, J Wong, S Shalapour, J Wan, W Zhang, ... Immunity 41 (6), 1052-1063, 2014 | 367 | 2014 |
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis T Moroishi, HW Park, B Qin, Q Chen, Z Meng, SW Plouffe, K Taniguchi, ... Genes & development 29 (12), 1271-1284, 2015 | 364 | 2015 |
Fructose stimulated de novo lipogenesis is promoted by inflammation J Todoric, G Di Caro, S Reibe, DC Henstridge, CR Green, A Vrbanac, ... Nature metabolism 2 (10), 1034-1045, 2020 | 274 | 2020 |
The commonly used antimicrobial additive triclosan is a liver tumor promoter MF Yueh, K Taniguchi, S Chen, RM Evans, BD Hammock, M Karin, ... Proceedings of the National Academy of Sciences 111 (48), 17200-17205, 2014 | 270 | 2014 |
Clinical and mutational spectrum of neurofibromatosis type 1–like syndrome L Messiaen, S Yao, H Brems, T Callens, A Sathienkijkanchai, E Denayer, ... Jama 302 (19), 2111-2118, 2009 | 228 | 2009 |
Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition A Umemura, EJ Park, K Taniguchi, JH Lee, S Shalapour, MA Valasek, ... Cell metabolism 20 (1), 133-144, 2014 | 190 | 2014 |
TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis S Inokuchi-Shimizu, EJ Park, YS Roh, L Yang, B Zhang, J Song, S Liang, ... The Journal of clinical investigation 124 (8), 3566-3578, 2014 | 185 | 2014 |
Inflammation-induced tumorigenesis and metastasis S Hibino, T Kawazoe, H Kasahara, S Itoh, T Ishimoto, ... International journal of molecular sciences 22 (11), 5421, 2021 | 183 | 2021 |
Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling E Sanchez-Lopez, E Flashner-Abramson, S Shalapour, Z Zhong, ... Oncogene 35 (20), 2634-2644, 2016 | 173 | 2016 |
Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation H Shaked, LJ Hofseth, A Chumanevich, AA Chumanevich, J Wang, ... Proceedings of the National Academy of Sciences 109 (35), 14007-14012, 2012 | 173 | 2012 |
Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia T Taketomi, D Yoshiga, K Taniguchi, T Kobayashi, A Nonami, R Kato, ... Nature neuroscience 8 (7), 855-857, 2005 | 156 | 2005 |