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Tsz Yin Chan
Tsz Yin Chan
Ph.D
Adresse e-mail validée de byu.edu
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The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions
KL Pennington, TY Chan, MP Torres, JL Andersen
Oncogene 37 (42), 5587-5604, 2018
3622018
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth
TY Chan, CM Egbert, JE Maxson, A Siddiqui, LJ Larsen, K Kohler, ...
Nature communications 12 (1), 1-17, 2021
232021
Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift
MMP Speirs, AC Swensen, TY Chan, PM Jones, JC Holman, MCB Harris, ...
Oncotarget 10 (4), 449, 2019
82019
Novel Binding Partners for CCT and PhLP1 Suggest a Common Folding Mechanism for WD40 Proteins with a 7-Bladed Beta-Propeller Structure
WS Mak, TM Tsang, TY Chan, GL Lukov
Proteomes 9 (4), 40, 2021
12021
Elucidation of a unique regulatory mechanism for TNK1 provides potential therapeutic targeting opportunities in cancer
TY Chan, C Egbert, L Larsen, J Tsang, J Maxson, E Roshan, CJ Whatcott, ...
Cancer Research 81 (13 Supplement), 2307-2307, 2021
12021
The ubiquitin-binding non-receptor tyrosine kinase TNK1 is regulated by a MARK-mediated interaction with 14-3-3
CM Egbert, TY Chan, L Larsen, ER Balasooriya, K Kohler, J Tsang, ...
Cancer Research 81 (13 Supplement), 2306-2306, 2021
2021
Discovery of a Novel Regulatory Mechanism of TNK1 by 14-3-3 and Its Ubiquitin Association Domain Provides a Potential Therapeutic Targeting Opportunity in Cancer
TY Chan
Brigham Young University, 2020
2020
Immune Inflammatory Consequences of Mutations in the Autophagy Gene ATG9A
PJ Hauk, MJ Morgan, C Banks, TY Chan, JK Abbott, M Schedel, ...
Journal of Allergy and Clinical Immunology 139 (2), AB388, 2017
2017
Lipidomic profiling identifies modified sphingosine kinase 1 regulation, and cell-fate signaling in pancreatic cancer
AC Swensen, TY Chan, JL Andersen, JT Prince, JC Price
Investigation of Dynamic Biological Systems Using Direct Injection and …, 2016
2016
14-3-3z-mediated oncogenic signaling downstream of HER2 in breast cancer
TY Chan, C Banks, B Peterson, J Andersen
Cancer Research 76 (14 Supplement), 4568-4568, 2016
2016
Mutations of the LYL1 gene in patients with T‐cell acute lymphoblastic leukemia (59.7)
TY Chan, F Zohren, B Ballard, M Goodell, K Rabin, G Lukov
The FASEB Journal 28, 59.7, 2014
2014
Phosducin‐like protein and CCT interact with G protein β‐like, β propeller proteins (567.4)
TM Tsang, WS Mak, TY Chan, G Lukov
The FASEB Journal 28, 567.4, 2014
2014
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