The dynamic and stress-adaptive signaling hub of 14-3-3: emerging mechanisms of regulation and context-dependent protein–protein interactions KL Pennington, TY Chan, MP Torres, JL Andersen Oncogene 37 (42), 5587-5604, 2018 | 362 | 2018 |
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth TY Chan, CM Egbert, JE Maxson, A Siddiqui, LJ Larsen, K Kohler, ... Nature communications 12 (1), 1-17, 2021 | 23 | 2021 |
Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift MMP Speirs, AC Swensen, TY Chan, PM Jones, JC Holman, MCB Harris, ... Oncotarget 10 (4), 449, 2019 | 8 | 2019 |
Novel Binding Partners for CCT and PhLP1 Suggest a Common Folding Mechanism for WD40 Proteins with a 7-Bladed Beta-Propeller Structure WS Mak, TM Tsang, TY Chan, GL Lukov Proteomes 9 (4), 40, 2021 | 1 | 2021 |
Elucidation of a unique regulatory mechanism for TNK1 provides potential therapeutic targeting opportunities in cancer TY Chan, C Egbert, L Larsen, J Tsang, J Maxson, E Roshan, CJ Whatcott, ... Cancer Research 81 (13 Supplement), 2307-2307, 2021 | 1 | 2021 |
The ubiquitin-binding non-receptor tyrosine kinase TNK1 is regulated by a MARK-mediated interaction with 14-3-3 CM Egbert, TY Chan, L Larsen, ER Balasooriya, K Kohler, J Tsang, ... Cancer Research 81 (13 Supplement), 2306-2306, 2021 | | 2021 |
Discovery of a Novel Regulatory Mechanism of TNK1 by 14-3-3 and Its Ubiquitin Association Domain Provides a Potential Therapeutic Targeting Opportunity in Cancer TY Chan Brigham Young University, 2020 | | 2020 |
Immune Inflammatory Consequences of Mutations in the Autophagy Gene ATG9A PJ Hauk, MJ Morgan, C Banks, TY Chan, JK Abbott, M Schedel, ... Journal of Allergy and Clinical Immunology 139 (2), AB388, 2017 | | 2017 |
Lipidomic profiling identifies modified sphingosine kinase 1 regulation, and cell-fate signaling in pancreatic cancer AC Swensen, TY Chan, JL Andersen, JT Prince, JC Price Investigation of Dynamic Biological Systems Using Direct Injection and …, 2016 | | 2016 |
14-3-3z-mediated oncogenic signaling downstream of HER2 in breast cancer TY Chan, C Banks, B Peterson, J Andersen Cancer Research 76 (14 Supplement), 4568-4568, 2016 | | 2016 |
Mutations of the LYL1 gene in patients with T‐cell acute lymphoblastic leukemia (59.7) TY Chan, F Zohren, B Ballard, M Goodell, K Rabin, G Lukov The FASEB Journal 28, 59.7, 2014 | | 2014 |
Phosducin‐like protein and CCT interact with G protein β‐like, β propeller proteins (567.4) TM Tsang, WS Mak, TY Chan, G Lukov The FASEB Journal 28, 567.4, 2014 | | 2014 |