| Matrix metalloproteinases in tumor–host cell communication CC Lynch, LM Matrisian Differentiation: REVIEW 70 (9‐10), 561-573, 2002 | 500 | 2002 |
| Moving targets: Emerging roles for MMPs in cancer progression and metastasis G Shay, CC Lynch, B Fingleton Matrix biology 44, 200-206, 2015 | 475 | 2015 |
| MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL CC Lynch, A Hikosaka, HB Acuff, MD Martin, N Kawai, RK Singh, ... Cancer cell 7 (5), 485-496, 2005 | 473 | 2005 |
| Lipopolysaccharide‐induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion JH Harmey, CD Bucana, W Lu, AM Byrne, S McDonnell, C Lynch, ... International journal of cancer 101 (5), 415-422, 2002 | 352 | 2002 |
| Development of a novel fluorogenic proteolytic beacon for in vivo detection and imaging of tumour-associated matrix metalloproteinase-7 activity. JO McIntyre, B Fingleton, KS Wells, DW Piston, CC Lynch, S Gautam, ... Biochemical Journal 377 (Pt 3), 617, 2004 | 198 | 2004 |
| Differential effects between the loss of MMP‐2 and MMP‐9 on structural and tissue‐level properties of bone JS Nyman, CC Lynch, DS Perrien, S Thiolloy, EC O'Quinn, CA Patil, X Bi, ... Journal of Bone and Mineral Research 26 (6), 1252-1260, 2011 | 145 | 2011 |
| Effect of ablation or inhibition of stromal matrix metalloproteinase-9 on lung metastasis in a breast cancer model is dependent on genetic background MD Martin, KJ Carter, SR Jean-Philippe, M Chang, S Mobashery, ... Cancer research 68 (15), 6251-6259, 2008 | 143 | 2008 |
| Mesenchymal stem cells promote mammary cancer cell migration in vitro via the CXCR2 receptor JL Halpern, A Kilbarger, CC Lynch Cancer letters 308 (1), 91-99, 2011 | 130 | 2011 |
| An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer A Araujo, LM Cook, CC Lynch, D Basanta Cancer research 74 (9), 2391-2401, 2014 | 110 | 2014 |
| Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis CC Lynch Bone 48 (1), 44-53, 2011 | 108 | 2011 |
| Raman and mechanical properties correlate at whole bone-and tissue-levels in a genetic mouse model X Bi, CA Patil, CC Lynch, GM Pharr, A Mahadevan-Jansen, JS Nyman Journal of biomechanics 44 (2), 297-303, 2011 | 107 | 2011 |
| Integrating new discoveries into the “vicious cycle” paradigm of prostate to bone metastases LM Cook, G Shay, A Aruajo, CC Lynch Cancer and Metastasis Reviews 33, 511-525, 2014 | 97 | 2014 |
| Role of matrix metalloproteinases in normal and disease processes S McDonnell, M Morgan, C Lynch Biochemical Society Transactions 27 (4), 734-740, 1999 | 93 | 1999 |
| New approaches to selectively target cancer-associated matrix metalloproteinase activity M Tauro, J McGuire, CC Lynch Cancer and metastasis reviews 33, 1043-1057, 2014 | 90 | 2014 |
| Osteoclast-derived matrix metalloproteinase-9 directly affects angiogenesis in the prostate tumor–bone microenvironment A Bruni-Cardoso, LC Johnson, RL Vessella, TE Peterson, CC Lynch Molecular Cancer Research 8 (4), 459-470, 2010 | 85 | 2010 |
| Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor CC Lynch, T Vargo-Gogola, MD Martin, B Fingleton, HC Crawford, ... Cancer research 67 (14), 6760-6767, 2007 | 83 | 2007 |
| Osteoclast-derived matrix metalloproteinase-7, but not matrix metalloproteinase-9, contributes to tumor-induced osteolysis S Thiolloy, J Halpern, GE Holt, HS Schwartz, GR Mundy, LM Matrisian, ... Cancer research 69 (16), 6747-6755, 2009 | 78 | 2009 |
| Cutting to the chase: how matrix metalloproteinase-2 activity controls breast-cancer-to-bone metastasis M Tauro, CC Lynch Cancers 10 (6), 185, 2018 | 75 | 2018 |
| Dissecting the multiple myeloma-bone microenvironment reveals new therapeutic opportunities G Shay, L Hazlehurst, CC Lynch Journal of Molecular Medicine 94, 21-35, 2016 | 74 | 2016 |
| Cleavage of E‐cadherin by matrix metalloproteinase‐7 promotes cellular proliferation in nontransformed cell lines via activation of RhoA CC Lynch, T Vargo-Gogola, LM Matrisian, B Fingleton Journal of Oncology 2010 (1), 530745, 2010 | 72 | 2010 |
