Suivre
Xin Li, PhD
Xin Li, PhD
Instructor/Faculty at BCM - Baylor College of Medicine
Adresse e-mail validée de bcm.edu - Page d'accueil
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Année
Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy
X Li, Y Song
Journal of Hematology & Oncology 13, 1-14, 2020
3542020
Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
JJ Qin, X Li, C Hunt, W Wang, H Wang, R Zhang
Genes & diseases 5 (3), 204-219, 2018
992018
Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ
X Li, J Sheng, G Huang, R Ma, F Yin, D Song, C Zhao, S Ma
European journal of medicinal chemistry 97, 32-41, 2015
822015
Targeting MDM2 for novel molecular therapy: Beyond oncology
W Wang, JJ Qin, M Rajaei, X Li, X Yu, C Hunt, R Zhang
Medicinal Research Reviews 40 (3), 856-880, 2020
762020
Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ
X Li, S Ma
European journal of medicinal chemistry 95, 1-15, 2015
642015
Structure, function and inhibition of critical protein–protein interactions involving mixed lineage leukemia 1 and its fusion oncoproteins
X Li, Y Song
Journal of Hematology & Oncology 14 (1), 1-33, 2021
592021
Structure and function of SARS-CoV and SARS-CoV-2 main proteases and their inhibition: A comprehensive review
X Li, Y Song
European Journal of Medicinal Chemistry, 115772, 2023
532023
MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53
W Wang, JW Cheng, JJ Qin, B Hu, X Li, B Nijampatnam, SE Velu, J Fan, ...
Cancer letters 459, 156-167, 2019
452019
A Novel Inhibitor of MDM2 Oncogene Blocks Metastasis of Hepatocellular Carcinoma and Overcomes Chemoresistance
RZ Wei Wang, Bo Hu, Jiang-Jiang Qin, Jianwen Cheng, Xin Li, Mehrdad Rajaeia ...
Genes & Diseases, 2019
422019
Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives
C Cong, H Wang, Y Hu, C Liu, S Ma, X Li, J Cao, S Ma
European journal of medicinal chemistry 46 (7), 3105-3111, 2011
342011
Targeting the NFAT1-MDM2-MDMX Network Inhibits the Proliferation and Invasion of Prostate Cancer Cells, Independent of p53 and Androgen
JJ Qin, X Li, W Wang, X Zi, R Zhang
Frontiers in Pharmacology 8, 917, 2017
302017
Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease
S Nie, J Zhao, X Wu, Y Yao, F Wu, YL Lin, X Li, AR Kneubehl, MB Vogt, ...
European journal of medicinal chemistry 225, 113767, 2021
272021
Prevention of prostate cancer by natural product MDM2 inhibitor GS25: in vitro and in vivo activities and molecular mechanisms
W Wang, JJ Qin, X Li, G Tao, Q Wang, X Wu, J Zhou, X Zi, R Zhang
Carcinogenesis 39 (8), 1026-1036, 2018
272018
Inhibiting β-catenin by β-carboline-type MDM2 inhibitor for pancreatic cancer therapy
JJ Qin, W Wang, X Li, R Zhang
Frontiers in pharmacology 9, 320167, 2018
252018
Synthesis and antibacterial evaluation of novel 11, 4 ″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria
X Li, S Ma, M Yan, Y Wang, S Ma
European journal of medicinal chemistry 59, 209-217, 2013
242013
Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth
F Wu, S Nie, Y Yao, T Huo, X Li, X Wu, J Zhao, YL Lin, Y Zhang, Q Mo, ...
Theranostics 11 (17), 8172, 2021
212021
A proteolysis-targeting chimera molecule selectively degrades ENL and inhibits malignant gene expression and tumor growth
X Li, Y Yao, F Wu, Y Song
Journal of Hematology & Oncology 15 (1), 41, 2022
192022
Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division
WC Chai, JJ Whittall, SW Polyak, K Foo, X Li, CJ Dutschke, AD Ogunniyi, ...
Frontiers in Microbiology, 3266, 2022
152022
Synthesis and Biological Evaluation of Novel FtsZ‐targeted 3‐arylalkoxy‐2, 6‐difluorobenzamides as Potential Antimicrobial Agents
S Qiang, C Wang, H Venter, X Li, Y Wang, L Guo, R Ma, S Ma
Chemical biology & drug design 87 (2), 257-264, 2016
152016
Synthesis and antibacterial activity of 4″-O-(trans-β-arylacrylamido)carbamoyl azithromycin analogs
M Yan, X Ma, R Dong, X Li, C Zhao, Z Guo, Y Shen, F Liu, R Ma, S Ma
European Journal of Medicinal Chemistry 103, 506-515, 2015
132015
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