Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis IR Holtman, DD Raj, JA Miller, W Schaafsma, Z Yin, N Brouwer, PD Wes, ... Acta neuropathologica communications 3 (1), 1-18, 2015 | 631 | 2015 |
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease ER Roy, B Wang, Y Wan, G Chiu, A Cole, Z Yin, NE Propson, Y Xu, ... The Journal of clinical investigation 130 (4), 1912-1930, 2020 | 405 | 2020 |
Microglia, lifestyle stress, and neurodegeneration C Madore, Z Yin, J Leibowitz, O Butovsky Immunity 52 (2), 222-240, 2020 | 276 | 2020 |
Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease Z Yin, D Raj, N Saiepour, D Van Dam, N Brouwer, IR Holtman, BJL Eggen, ... Neurobiology of aging 55, 115-122, 2017 | 256 | 2017 |
Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia C Wang, M Xiong, M Gratuze, X Bao, Y Shi, PS Andhey, M Manis, ... Neuron 109 (10), 1657-1674. e7, 2021 | 245 | 2021 |
Increased white matter inflammation in aging-and Alzheimer’s disease brain D Raj*, Z Yin*, M Breur, J Doorduin, IR Holtman, M Olah, ... Frontiers in molecular neuroscience 10, 206 (*co-first authors), 2017 | 176 | 2017 |
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints Z Yin, N Rosenzweig, KL Kleemann, X Zhang, W Brandão, MA Margeta, ... Nature immunology 24 (11), 1839-1853, 2023 | 83 | 2023 |
Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma MA Margeta, Z Yin, C Madore, KM Pitts, SM Letcher, J Tang, S Jiang, ... Immunity 55 (9), 1627-1644. e7, 2022 | 63 | 2022 |
Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease Z Yin, S Herron, S Silveira, K Kleemann, C Gauthier, D Mallah, Y Cheng, ... Nature neuroscience 26 (7), 1196-1207, 2023 | 58 | 2023 |
Low-fat diet with caloric restriction reduces white matter microglia activation during aging Z Yin, DD Raj, W Schaafsma, RA Van der Heijden, SM Kooistra, ... Frontiers in molecular neuroscience 11, 289342, 2018 | 49 | 2018 |
Sex-specific transcriptome of spinal microglia in neuropathic pain due to peripheral nerve injury NT Fiore, Z Yin, D Guneykaya, CD Gauthier, J Hayes, A D’Hary, ... Glia, 2022 | 39 | 2022 |
Progressive motor deficit is mediated by the denervation of neuromuscular junctions and axonal degeneration in transgenic mice expressing mutant (P301S) tau protein Z Yin, F Valkenburg, BE Hornix, I Mantingh-Otter, X Zhou, M Mari, ... Journal of Alzheimer's Disease 60 (s1), S41-S57, 2017 | 28 | 2017 |
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer’s-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative … H Shi, Z Yin, Y Koronyo, DT Fuchs, J Sheyn, MR Davis, JW Wilson, ... Acta Neuropathologica Communications 10 (1), 136, 2022 | 26 | 2022 |
Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males H Abou-El-Hassan, RM Rezende, S Izzy, G Gabriely, T Yahya, ... Nature Communications 14 (1), 4286, 2023 | 16 | 2023 |
Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder D Guneykaya, B Ugursu, F Logiacco, O Popp, MA Feiks, N Meyer, ... Brain, Behavior, and Immunity 111, 61-75, 2023 | 16 | 2023 |
Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models C Wasén, LC Beauchamp, J Vincentini, S Li, DS LeServe, C Gauthier, ... Nature Communications 15 (1), 3872, 2024 | 15 | 2024 |
Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease N Rosenzweig, KL Kleemann, T Rust, M Carpenter, M Grucci, M Aronchik, ... Nature Medicine, 1-14, 2024 | 9 | 2024 |
IL-33 promotes mouse keratinocyte-derived chemokine, an IL-8 homologue, expression in airway smooth muscle cells in ovalbumin-sensitized mice W Wu, Y Xu, X He, Y Lu, Y Guo, Z Yin, J Xie, J Zhao Asian Pac J Allergy Immunol 32 (4), 337-44, 2014 | 8 | 2014 |
Do neuroimaging results impact prognosis of epilepsy surgery? A meta-analysis Z Yin, H Kang, W Wu, M Wang, S Zhu Journal of Huazhong University of Science and Technology [Medical Sciences …, 2013 | 4 | 2013 |
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy W Brandao*, N Jain*, Z Yin*, KL Kleemann, M Carpenter, X Bao, ... Science Translational Medicine 17 (781), eadk3690 (*co-first authors), 2025 | | 2025 |