| The NaV1.7 sodium channel: from molecule to man SD Dib-Hajj, Y Yang, JA Black, SG Waxman Nature Reviews Neuroscience 14 (1), 49-62, 2013 | 638 | 2013 |
| Nav1. 8 expression is not restricted to nociceptors in mouse peripheral nervous system SD Shields, HS Ahn, Y Yang, C Han, RP Seal, JN Wood, SG Waxman, ... PAIN® 153 (10), 2017-2030, 2012 | 284 | 2012 |
| Small-fiber neuropathy Nav1. 8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons J Huang, Y Yang, P Zhao, MM Gerrits, JGJ Hoeijmakers, K Bekelaar, ... Journal of Neuroscience 33 (35), 14087-14097, 2013 | 141 | 2013 |
| Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel Y Yang, SD Dib-Hajj, J Zhang, Y Zhang, L Tyrrell, M Estacion, ... Nature communications 3 (1), 1186, 2012 | 106 | 2012 |
| The domain II S4-S5 linker in Nav1. 9: a missense mutation enhances activation, impairs fast inactivation, and produces human painful neuropathy C Han, Y Yang, BTA de Greef, JGJ Hoeijmakers, MM Gerrits, ... Neuromolecular medicine 17, 158-169, 2015 | 97 | 2015 |
| Pharmacotherapy for pain in a family with inherited erythromelalgia guided by genomic analysis and functional profiling P Geha, Y Yang, M Estacion, BR Schulman, H Tokuno, AV Apkarian, ... JAMA neurology 73 (6), 659-667, 2016 | 95 | 2016 |
| Resilience to pain: a peripheral component identified using induced pluripotent stem cells and dynamic clamp MA Mis, Y Yang, BS Tanaka, C Gomis-Perez, S Liu, F Dib-Hajj, T Adi, ... Journal of Neuroscience 39 (3), 382-392, 2019 | 94 | 2019 |
| PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors Y Shi, Z Wu, N Cui, W Shi, Y Yang, X Zhang, A Rojas, BT Ha, C Jiang American Journal of Physiology-Regulatory, Integrative and Comparative …, 2007 | 94 | 2007 |
| Nav1. 7-A1632G mutation from a family with inherited erythromelalgia: enhanced firing of dorsal root ganglia neurons evoked by thermal stimuli Y Yang, J Huang, MA Mis, M Estacion, L Macala, P Shah, BR Schulman, ... Journal of Neuroscience 36 (28), 7511-7522, 2016 | 86 | 2016 |
| Oxidative stress inhibits vascular KATP channels by S-glutathionylation Y Yang, W Shi, N Cui, Z Wu, C Jiang Journal of Biological Chemistry 285 (49), 38641-38648, 2010 | 82 | 2010 |
| NaV1. 7 as a pharmacogenomic target for pain: moving toward precision medicine Y Yang, MA Mis, M Estacion, SD Dib-Hajj, SG Waxman Trends in pharmacological sciences 39 (3), 258-275, 2018 | 73 | 2018 |
| Familial gain-of-function Nav1. 9 mutation in a painful channelopathy C Han, Y Yang, RH Te Morsche, JPH Drenth, JM Politei, SG Waxman, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (3), 233-240, 2017 | 71 | 2017 |
| Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ... Cell reports 36 (5), 2021 | 70 | 2021 |
| Functional elements on SIRPα IgV domain mediate cell surface binding to CD47 Y Liu, Q Tong, Y Zhou, HW Lee, JJ Yang, HJ Bühring, YT Chen, B Ha, ... Journal of molecular biology 365 (3), 680-693, 2007 | 66 | 2007 |
| Lipopolysaccharides up-regulate Kir6. 1/SUR2B channel expression and enhance vascular KATP channel activity via NF-κB-dependent signaling W Shi, N Cui, Z Wu, Y Yang, S Zhang, H Gai, D Zhu, C Jiang Journal of Biological Chemistry 285 (5), 3021-3029, 2010 | 63 | 2010 |
| Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10. 2–R327H demonstrate the role of this residue in stabilizing the channel closed state Y Yang, DV Vasylyev, F Dib-Hajj, KR Veeramah, MF Hammer, ... Journal of Neuroscience 33 (42), 16586-16593, 2013 | 57 | 2013 |
| KATP channel action in vascular tone regulation: from genetics to diseases SHI Wei-Wei, Y Yang, SHI Yun, J Chun Sheng li xue bao:[Acta physiologica Sinica] 64 (1), 1, 2012 | 54 | 2012 |
| Molecular basis and structural insight of vascular KATP channel gating by S-glutathionylation Y Yang, W Shi, X Chen, N Cui, AS Konduru, Y Shi, TC Trower, S Zhang, ... Journal of Biological Chemistry 286 (11), 9298-9307, 2011 | 53 | 2011 |
| PKA-dependent activation of the vascular smooth muscle isoform of KATP channels by vasoactive intestinal polypeptide and its effect on relaxation of the mesenteric resistance … Y Yang, Y Shi, S Guo, S Zhang, N Cui, W Shi, D Zhu, C Jiang Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (1), 88-96, 2008 | 53 | 2008 |
| Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury X Chen, J Zhang, Y Song, P Yang, Y Yang, Z Huang, K Wang Acta Pharmaceutica Sinica B 10 (9), 1634-1645, 2020 | 51 | 2020 |
Stephen G. WaxmanYaleAdresse e-mail validée de yale.edu
