| Targeting ferroptosis as a vulnerability in cancer G Lei, L Zhuang, B Gan Nature Reviews Cancer 22 (7), 381-396, 2022 | 1347 | 2022 |
| DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 593 (7860), 586-590, 2021 | 1231 | 2021 |
| The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression G Lei, Y Zhang, P Koppula, X Liu, J Zhang, SH Lin, JA Ajani, Q Xiao, ... Cell research 30 (2), 146-162, 2020 | 926 | 2020 |
| Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ... Nature cell biology 25 (3), 404-414, 2023 | 607 | 2023 |
| mTORC1 couples cyst (e) ine availability with GPX4 protein synthesis and ferroptosis regulation Y Zhang, RV Swanda, L Nie, X Liu, C Wang, H Lee, G Lei, C Mao, ... Nature communications 12 (1), 1-14, 2021 | 497 | 2021 |
| Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer X Liu, K Olszewski, Y Zhang, EW Lim, J Shi, X Zhang, J Zhang, H Lee, ... Nature cell biology 22 (4), 476-486, 2020 | 397 | 2020 |
| Ferroptosis, radiotherapy, and combination therapeutic strategies G Lei, C Mao, Y Yan, L Zhuang, B Gan Protein & cell 12 (11), 836-857, 2021 | 310 | 2021 |
| A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ... Nature communications 13 (1), 2206, 2022 | 272 | 2022 |
| PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer T Hong, G Lei, X Chen, H Li, X Zhang, N Wu, Y Zhao, Y Zhang, J Wang Redox biology 42, 101928, 2021 | 235 | 2021 |
| Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ... Oncogene 40 (20), 3533-3547, 2021 | 145 | 2021 |
| SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells Y Yan, H Teng, Q Hang, L Kondiparthi, G Lei, A Horbath, X Liu, C Mao, ... Nature communications 14 (1), 3673, 2023 | 122 | 2023 |
| The roles of ferroptosis in cancer: tumor suppression, tumor microenvironment, and therapeutic interventions G Lei, L Zhuang, B Gan Cancer cell 42 (4), 513-534, 2024 | 62 | 2024 |
| mTORC1 and ferroptosis: Regulatory mechanisms and therapeutic potential G Lei, L Zhuang, B Gan Bioessays 43 (8), 2100093, 2021 | 61 | 2021 |
| Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma S Song, Q Chen, Y Li, G Lei, A Scott, L Huo, CY Li, JS Estrella, A Correa, ... Gut 70 (12), 2238-2248, 2021 | 50 | 2021 |
| The beneficial role of sunitinib in tumor immune surveillance by regulating tumor PD‐L1 H Li, X Kuang, L Liang, Y Ye, YC Zhang, J Li, F Ma, J Tao, G Lei, S Zhao, ... Advanced Science 8 (2), 2001596, 2021 | 50 | 2021 |
| KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition P Koppula, K Olszewski, Y Zhang, L Kondiparthi, X Liu, G Lei, M Das, ... Iscience 24 (6), 2021 | 44 | 2021 |
| Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance H Lee, A Horbath, L Kondiparthi, JK Meena, G Lei, S Dasgupta, X Liu, ... Nature communications 15 (1), 79, 2024 | 36 | 2024 |
| H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death Y Zhang, J Shi, X Liu, Z Xiao, G Lei, H Lee, P Koppula, W Cheng, C Mao, ... Cancer research 80 (11), 2243-2256, 2020 | 34 | 2020 |
| Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 596 (7873), E13-E13, 2021 | 21 | 2021 |
| PKCβII–ACSL4 pathway mediating ferroptosis execution and anti‐tumor immunity G Lei, A Horbath, Z Li, B Gan Cancer Communications 42 (7), 583, 2022 | 19 | 2022 |