Juan Carlos Acosta Cobacho

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Ana BanitoGerman Cancer Research Center (DKFZ)Adresse e-mail validée de kitz-heidelberg.de
Lars ZenderProfessor of Medical Oncology, Director & Chair, Dept. of Medical Oncology & Pneumology, University Hospital Tübingen, 72076 Tübingen, GermanyAdresse e-mail validée de med.uni-tuebingen.de
Javier LeonInstituto de Biomedicina y Biotecnología de Cantabria (IBBTEC), Universidad de Cantabria, CSICAdresse e-mail validée de unican.es
Gopuraja DharmalingamEli Lilly and CompanyAdresse e-mail validée de lilly.com
thomas carrollDirector Of Bioinformatics, The Rockefeller UniversityAdresse e-mail validée de rockefeller.edu
Torsten WüstefeldAssociate Professor of Molecular Metabolism, LKC, NTUAdresse e-mail validée de ntu.edu.sg
Snijders apThe Francis Crick InstituteAdresse e-mail validée de crick.ac.uk
M. Dolores DelgadoProfessor University of Cantabria-IBBTECAdresse e-mail validée de unican.es
Salvador AZNAR BENITAHIRB Barcelona and ICREAAdresse e-mail validée de irbbarcelona.org
Ana O'LoghlenSpanish National Research Centre (CSIC - CIB)Adresse e-mail validée de cib.csic.es
gloria pascualAdresse e-mail validée de irbbarcelona.org
Catrin PritchardUniversity of LeicesterAdresse e-mail validée de le.ac.uk
marco da costamaitre de conference biologieAdresse e-mail validée de upmc.fr
Gareth J ThomasProfessor of Experimental Pathology, University of SouthamptonAdresse e-mail validée de soton.ac.uk
Juan Pedro Martinez-BarberaUCL GOS INSTITUTE OF CHILD HEALTH, DEVELOPMENTAL BIOLOGY AND CANCER, 30 GUILFORD STREET, WC1N 1EH, LONDON, UKAdresse e-mail validée de ucl.ac.uk
Nuria FerrandizCancer Research Center, IBMCC-CSICAdresse e-mail validée de usal.es
Joao PassosProfessor, Mayo Clinic, MN, USAAdresse e-mail validée de mayo.edu
Timothy KendallChair of Liver Pathology, University of EdinburghAdresse e-mail validée de ed.ac.uk
Irene Fernández-DuranInstitut d'Investigació contra la Leucèmia Josep CarrerasAdresse e-mail validée de carrerasresearch.org
Sofia Ferreira-GonzalezCIR, Institute for Regeneration and Repair, University of EdinburghAdresse e-mail validée de ed.ac.uk

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Juan Carlos Acosta Cobacho

Institute of Biomedicine and Biotechnology of Cantabria, Universidad de Cantabria, CSIC

Adresse e-mail validée de unican.es - Page d'accueil

Cellular Senescence SASP innate immune signalling cancer molecular biology


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
A complex secretory program orchestrated by the inflammasome controls paracrine senescence JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ... Nature cell biology 15 (8), 978-990, 2013	2173	2013
Chemokine signaling via the CXCR2 receptor reinforces senescence JC Acosta, A O'Loghlen, A Banito, MV Guijarro, A Augert, S Raguz, ... cell 133 (6), 1006-1018, 2008	1977	2008
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (9), 1205-1217, 2015	742	2015
Senescence impairs successful reprogramming to pluripotent stem cells A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ... Genes & development 23 (18), 2134-2139, 2009	730	2009
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS M Barradas, E Anderton, JC Acosta, SD Li, A Banito, ... Genes & development 23 (10), 1177-1182, 2009	401	2009
Senescence: a new weapon for cancer therapy JC Acosta, J Gil Trends in cell biology 22 (4), 211-219, 2012	285	2012
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ... Nature Communications 9 (1), 1020, 2018	151	2018
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype P Hari, FR Millar, N Tarrats, J Birch, A Quintanilla, CJ Rink, ... Science advances 5 (6), eaaw0254, 2019	141	2019
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León Journal of Biological Chemistry 280 (18), 18120-18129, 2005	126	2005
Notch signaling mediates secondary senescence YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ... Cell reports 27 (4), 997-1007. e5, 2019	119	2019
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27KIP1 through SKP2 in human leukemia cells G Bretones, JC Acosta, JM Caraballo, N Ferrándiz, MT Gómez-Casares, ... Journal of Biological Chemistry 286 (11), 9815-9825, 2011	119	2011
Suppression of autophagy impedes glioblastoma development and induces senescence N Gammoh, J Fraser, C Puente, HM Syred, H Kang, T Ozawa, D Lam, ... Autophagy 12 (9), 1431-1439, 2016	114	2016
Control of senescence by CXCR2 and its ligands JC Acosta, A Loghlen, A Banito, S Raguz, J Gil Cell cycle 7 (19), 2956-2959, 2008	113	2008
A role for CXCR2 in senescence, but what about in cancer? JC Acosta, J Gil Cancer research 69 (6), 2167-2170, 2009	106	2009
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, ... Journal of Experimental Medicine 214 (6), 1691-1710, 2017	94	2017
Nuclear pore density controls heterochromatin reorganization during senescence C Boumendil, P Hari, KCF Olsen, JC Acosta, WA Bickmore Genes & Development 33 (3-4), 144-149, 2019	93	2019
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? J Leon, N Ferrandiz, JC Acosta, MD Delgado Cell cycle 8 (8), 1148-1157, 2009	91	2009
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest JC Acosta, N Ferrándiz, G Bretones, V Torrano, R Blanco, C Richard, ... Molecular and cellular biology, 2008	85	2008
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib M Albajar, MT Gómez-Casares, J Llorca, I Mauleon, JP Vaqué, JC Acosta, ... Molecular Cancer Research 9 (5), 564-576, 2011	81	2011
PHD3 regulates p53 protein stability by hydroxylating proline 359 J Rodriguez, A Herrero, S Li, N Rauch, A Quintanilla, K Wynne, A Krstic, ... Cell reports 24 (5), 1316-1329, 2018	72	2018

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