The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling M Carty, R Goodbody, M Schröder, J Stack, PN Moynagh, AG Bowie Nature immunology 7 (10), 1074-1081, 2006 | 724 | 2006 |
BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis JE Quinn, RD Kennedy, PB Mullan, PM Gilmore, M Carty, PG Johnston, ... Cancer research 63 (19), 6221-6228, 2003 | 597 | 2003 |
Detection of viral infections by innate immunity M Carty, C Guy, AG Bowie Biochemical pharmacology 183, 114316, 2021 | 358 | 2021 |
Evaluating the role of Toll-like receptors in diseases of the central nervous system M Carty, AG Bowie Biochemical pharmacology 81 (7), 825-837, 2011 | 203 | 2011 |
Recent insights into the role of Toll-like receptors in viral infection M Carty, AG Bowie Clinical & Experimental Immunology 161 (3), 397-406, 2010 | 161 | 2010 |
Cell survival and cytokine release after inflammasome activation is regulated by the Toll-IL-1R protein SARM M Carty, J Kearney, KA Shanahan, E Hams, R Sugisawa, D Connolly, ... Immunity 50 (6), 1412-1424. e6, 2019 | 139 | 2019 |
Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle JC Hedges, BC Oxhorn, M Carty, LP Adam, IA Yamboliev, WT Gerthoffer American Journal of Physiology-Cell Physiology 278 (4), C718-C726, 2000 | 125 | 2000 |
Innate antiviral signalling in the central nervous system M Carty, L Reinert, SR Paludan, AG Bowie Trends in immunology 35 (2), 79-87, 2014 | 79 | 2014 |
BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3 PM Gilmore, N McCabe, JE Quinn, RD Kennedy, JJ Gorski, HN Andrews, ... Cancer research 64 (12), 4148-4154, 2004 | 62 | 2004 |
SARM: From immune regulator to cell executioner M Carty, AG Bowie Biochemical pharmacology 161, 52-62, 2019 | 55 | 2019 |
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration E Ozaki, L Gibbons, NGB Neto, P Kenna, M Carty, M Humphries, ... Life science alliance 3 (5), 2020 | 53 | 2020 |
Coupling of M2 muscarinic receptors to ERK MAP kinases and caldesmon phosphorylation in colonic smooth muscle AK Cook, M Carty, CA Singer, IA Yamboliev, WT Gerthoffer American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (3 …, 2000 | 50 | 2000 |
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation F Gu, A Krüger, HG Roggenkamp, R Alpers, D Lodygin, V Jaquet, F Möckl, ... Science signaling 14 (709), eabe3800, 2021 | 41 | 2021 |
SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter C Gürtler, M Carty, J Kearney, SA Schattgen, A Ding, KA Fitzgerald, ... The Journal of Immunology 192 (10), 4821-4832, 2014 | 34 | 2014 |
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, ECO Brien, ... Nature Communications 14 (1), 3513, 2023 | 26 | 2023 |
Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses A Dempsey, SE Keating, M Carty, AG Bowie Journal of Biological Chemistry 293 (39), 14989-15001, 2018 | 24 | 2018 |
Alum activates the bovine NLRP3 inflammasome C Harte, AL Gorman, S McCluskey, M Carty, AG Bowie, CJ Scott, ... Frontiers in Immunology 8, 1494, 2017 | 24 | 2017 |
Role played by BRCA1 in regulating the cellular response to stress PM Gilmore, JE Quinn, PB Mullan, HN Andrews, N McCabe, M Carty, ... Biochemical Society Transactions 31 (1), 257-262, 2003 | 22 | 2003 |
SARM1 ablation is protective and preserves spatial vision in an in vivo mouse model of retinal ganglion cell degeneration LK Finnegan, N Chadderton, PF Kenna, A Palfi, M Carty, AG Bowie, ... International Journal of Molecular Sciences 23 (3), 1606, 2022 | 20 | 2022 |
CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages CG Doran, R Sugisawa, M Carty, F Roche, C Fergus, K Hokamp, VP Kelly, ... Journal of Biological Chemistry 297 (6), 2021 | 19 | 2021 |