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Christoph Schultheiß
Christoph Schultheiß
University Hospital Basel, Department of Biomedicine
Adresse e-mail validée de unibas.ch - Page d'accueil
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The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
C Schultheiß, E Willscher, L Paschold, C Gottschick, B Klee, SS Henkes, ...
Cell Reports Medicine 3 (6), 100663, 2022
3632022
Next-generation sequencing of T and B cell receptor repertoires from COVID-19 patients showed signatures associated with severity of disease
C Schultheiß, L Paschold, D Simnica, M Mohme, E Willscher, ...
Immunity 53 (2), 442-455. e4, 2020
3362020
HLA class I–associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children
RA Porritt, L Paschold, MN Rivas, MH Cheng, LM Yonker, H Chandnani, ...
The Journal of Clinical Investigation 131 (10), 2021
1962021
Clonal expansion and activation of tissue-resident memory-like TH17 cells expressing GM-CSF in the lungs of patients with severe COVID-19
Y Zhao, C Kilian, JE Turner, L Bosurgi, K Roedl, P Bartsch, AC Gnirck, ...
Science Immunology 6 (56), eabf6692, 2021
1692021
Liquid biomarkers of macrophage dysregulation and circulating spike protein illustrate the biological heterogeneity in patients with post‐acute sequelae of COVID‐19
C Schultheiß, E Willscher, L Paschold, C Gottschick, B Klee, L Bosurgi, ...
Journal of Medical Virology 95 (1), e28364, 2023
642023
Efficacy of Ipilimumab vs FOLFOX in combination with Nivolumab and Trastuzumab in patients with previously untreated ERBB2-positive esophagogastric adenocarcinoma: The AIO …
A Stein, L Paschold, J Tintelnot, E Goekkurt, SS Henkes, D Simnica, ...
JAMA oncology 8 (8), 1150-1158, 2022
602022
Next‐generation immunosequencing reveals pathological T‐cell architecture in autoimmune hepatitis
C Schultheiß, D Simnica, E Willscher, A Oberle, L Fanchi, N Bonzanni, ...
Hepatology 73 (4), 1436-1448, 2021
432021
PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
A Stein, D Simnica, C Schultheiß, R Scholz, J Tintelnot, E Gökkurt, ...
Journal for Immunotherapy of Cancer 9 (7), 2021
422021
Nanobody targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies
J Tintelnot, N Baum, C Schultheiß, F Braig, M Trentmann, J Finter, ...
Molecular Cancer Therapeutics 18 (4), 823-833, 2019
302019
Detection of SARS-CoV-2 derived small RNAs and changes in circulating small RNAs associated with COVID-19
C Grehl, C Schultheiss, K Hoffmann, M Binder, T Altmann, I Grosse, ...
Viruses 13 (8), 1593, 2021
292021
SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
L von Wenserski, C Schultheiß, S Bolz, S Schliffke, D Simnica, E Willscher, ...
Leukemia 35 (4), 1073-1086, 2021
292021
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
C Schultheiß, L Paschold, E Willscher, D Simnica, A Wöstemeier, ...
Iscience 24 (11), 2021
282021
SARS-CoV-2–specific antibody rearrangements in prepandemic immune repertoires of risk cohorts and patients with COVID-19
L Paschold, D Simnica, E Willscher, MJGT Vehreschild, J Dutzmann, ...
The Journal of clinical investigation 131 (1), 2021
282021
From online data collection to identification of disease mechanisms: The IL-1beta, IL-6 and TNF-alpha; cytokine triad is associated with post-acute sequelae of COVID-19 in a …
C Schultheiß, E Willscher, L Paschold, C Gottschick, B Klee, SS Henkes, ...
MedRxiv, 2021
282021
High-throughput immunogenetics reveals a lack of physiological T cell clusters in patients with autoimmune cytopenias
D Simnica, S Schliffke, C Schultheiß, N Bonzanni, LF Fanchi, N Akyüz, ...
Frontiers in Immunology 10, 1897, 2019
262019
B cells in autoimmune hepatitis: bystanders or central players?
C Schultheiß, S Steinmann, AW Lohse, M Binder
Seminars in Immunopathology 44 (4), 411-427, 2022
202022
Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
RA Porritt, L Paschold, MN Rivas, MH Cheng, LM Yonker, H Chandnani, ...
bioRxiv, 2020
202020
Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts
D Simnica, C Schultheiß, M Mohme, L Paschold, E Willscher, A Fitzek, ...
Clinical & Translational Immunology 10 (9), e1340, 2021
192021
Translational analysis and final efficacy of the AVETUX trial–Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
J Tintelnot, I Ristow, M Sauer, D Simnica, C Schultheiß, R Scholz, ...
Frontiers in Oncology 12, 993611, 2022
182022
Rapid hypermutation B cell trajectory recruits previously primed B cells upon third SARS-CoV-2 mRNA vaccination
L Paschold, B Klee, C Gottschick, E Willscher, S Diexer, C Schultheiß, ...
Frontiers in Immunology 13, 2022
152022
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