| CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer DJ Weisenberger, KD Siegmund, M Campan, J Young, TI Long, ... Nature genetics 38 (7), 787-793, 2006 | 2367 | 2006 |
| A Big Bang model of human colorectal tumor growth A Sottoriva, H Kang, Z Ma, TA Graham, MP Salomon, J Zhao, P Marjoram, ... Nature genetics 47 (3), 209-216, 2015 | 1172 | 2015 |
| Low-level processing of Illumina Infinium DNA methylation beadarrays TJ Triche Jr, DJ Weisenberger, D Van Den Berg, PW Laird, KD Siegmund Nucleic acids research 41 (7), e90-e90, 2013 | 881 | 2013 |
| DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons KD Siegmund, CM Connor, M Campan, TI Long, DJ Weisenberger, ... PloS one 2 (9), e895, 2007 | 526 | 2007 |
| Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression SA Selamat, BS Chung, L Girard, W Zhang, Y Zhang, M Campan, ... Genome research 22 (7), 1197-1211, 2012 | 514 | 2012 |
| Recommendations for the design and analysis of epigenome-wide association studies KB Michels, AM Binder, S Dedeurwaerder, CB Epstein, JM Greally, I Gut, ... Nature methods 10 (10), 949-955, 2013 | 433 | 2013 |
| Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen M Widschwendter, KD Siegmund, HM Müller, H Fiegl, C Marth, ... Cancer research 64 (11), 3807-3813, 2004 | 424 | 2004 |
| Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm S Houshdaran, VK Cortessis, K Siegmund, A Yang, PW Laird, RZ Sokol PloS one 2 (12), e1289, 2007 | 367 | 2007 |
| Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer EM Wolff, HM Byun, HF Han, S Sharma, PW Nichols, KD Siegmund, ... PLoS genetics 6 (4), e1000917, 2010 | 357 | 2010 |
| Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships VK Cortessis, DC Thomas, AJ Levine, CV Breton, TM Mack, KD Siegmund, ... Human genetics 131, 1565-1589, 2012 | 356 | 2012 |
| Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data Y Liu, KD Siegmund, PW Laird, BP Berman Genome biology 13, 1-14, 2012 | 308 | 2012 |
| Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue-and individual-specific DNA methylation patterns HM Byun, KD Siegmund, F Pan, DJ Weisenberger, G Kanel, PW Laird, ... Human molecular genetics 18 (24), 4808-4817, 2009 | 304 | 2009 |
| Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening JN Poynter, KD Siegmund, DJ Weisenberger, TI Long, SN Thibodeau, ... Cancer Epidemiology Biomarkers & Prevention 17 (11), 3208-3215, 2008 | 276 | 2008 |
| Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients MG Friedrich, DJ Weisenberger, JC Cheng, S Chandrasoma, ... Clinical Cancer Research 10 (22), 7457-7465, 2004 | 267 | 2004 |
| Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue EM Wolff, Y Chihara, F Pan, DJ Weisenberger, KD Siegmund, K Sugano, ... Cancer research 70 (20), 8169-8178, 2010 | 225 | 2010 |
| The PREMM1, 2, 6 model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history F Kastrinos, EW Steyerberg, R Mercado, J Balmaña, S Holter, S Gallinger, ... Gastroenterology 140 (1), 73-81. e5, 2011 | 205 | 2011 |
| Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers KD Siegmund, P Marjoram, YJ Woo, S Tavaré, D Shibata Proceedings of the National Academy of Sciences 106 (12), 4828-4833, 2009 | 186 | 2009 |
| The methylenetetrahydrofolate reductase 677C→ T polymorphism and distal colorectal adenoma risk AJ Levine, KD Siegmund, CM Ervin, A Diep, ER Lee, HD Frankl, ... Cancer Epidemiology Biomarkers & Prevention 9 (7), 657-663, 2000 | 169 | 2000 |
| DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma SA Selamat, JS Galler, AD Joshi, MN Fyfe, M Campan, KD Siegmund, ... PloS one 6 (6), e21443, 2011 | 165 | 2011 |
| Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status JN Poynter, RW Haile, KD Siegmund, PT Campbell, JC Figueiredo, ... Cancer epidemiology, biomarkers & prevention 18 (10), 2745-2750, 2009 | 164 | 2009 |
Peter W. LairdVan Andel InstituteAdresse e-mail validée de vai.org
