Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons ST Schafer, ACM Paquola, S Stern, D Gosselin, M Ku, M Pena, TJM Kuret, ... Nature neuroscience 22 (2), 243-255, 2019 | 259 | 2019 |
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetzki, L Böhnke, ... Cell stem cell 28 (9), 1533-1548. e6, 2021 | 195 | 2021 |
Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium S Stern, R Santos, MC Marchetto, APD Mendes, GA Rouleau, S Biesmans, ... Molecular psychiatry 23 (6), 1453-1465, 2018 | 179 | 2018 |
Efficient generation of CA3 neurons from human pluripotent stem cells enables modeling of hippocampal connectivity in vitro A Sarkar, A Mei, ACM Paquola, S Stern, C Bardy, JR Klug, S Kim, ... Cell stem cell 22 (5), 684-697. e9, 2018 | 137 | 2018 |
An epilepsy-associated KCNT1 mutation enhances excitability of human iPSC-derived neurons by increasing slack KNa currents IH Quraishi, S Stern, KP Mangan, Y Zhang, SR Ali, MR Mercier, ... Journal of Neuroscience 39 (37), 7438-7449, 2019 | 94 | 2019 |
Cooperativity, specificity, and evolutionary stability of Polycomb targeting in Drosophila B Schuettengruber, NO Elkayam, T Sexton, M Entrevan, S Stern, ... Cell reports 9 (1), 219-233, 2014 | 81 | 2014 |
Prediction of response to drug therapy in psychiatric disorders S Stern, S Linker, KC Vadodaria, MC Marchetto, FH Gage Open biology 8 (5), 180031, 2018 | 65 | 2018 |
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients R Santos, SB Linker, S Stern, APD Mendes, MN Shokhirev, G Erikson, ... Molecular psychiatry 26 (6), 2440-2456, 2021 | 60 | 2021 |
Mechanisms underlying the hyperexcitability of CA3 and dentate gyrus hippocampal neurons derived from patients with bipolar disorder S Stern, A Sarkar, T Stern, A Mei, APD Mendes, Y Stern, G Goldberg, ... Biological psychiatry 88 (2), 139-149, 2020 | 55 | 2020 |
Serotonin in psychiatry: in vitro disease modeling using patient-derived neurons KC Vadodaria, S Stern, MC Marchetto, FH Gage Cell and tissue research 371, 161-170, 2018 | 48 | 2018 |
Modeling genetic epileptic encephalopathies using brain organoids DJ Steinberg, S Repudi, A Saleem, I Kustanovich, S Viukov, B Abudiab, ... EMBO Molecular Medicine 13 (8), e13610, 2021 | 43 | 2021 |
Brain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms of Parkinson's Disease Advanced Materials, 2023 | 42 | 2023 |
IQSEC2 mutation associated with epilepsy, intellectual disability, and autism results in hyperexcitability of patient-derived neurons and deficient synaptic transmission B Brant, T Stern, HA Shekhidem, L Mizrahi, I Rosh, Y Stern, P Ofer, ... Molecular psychiatry 26 (12), 7498-7508, 2021 | 37 | 2021 |
The NO answer for autism spectrum disorder MK Tripathi, SK Ojha, M Kartawy, W Hamoudi, A Choudhary, S Stern, ... Advanced Science 10 (22), 2205783, 2023 | 35 | 2023 |
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients S Stern, S Lau, A Manole, I Rosh, MM Percia, R Ben Ezer, MN Shokhirev, ... npj Parkinson's Disease 8 (1), 103, 2022 | 34 | 2022 |
A physiological instability displayed in hippocampal neurons derived from lithium-nonresponsive bipolar disorder patients S Stern, A Sarkar, D Galor, T Stern, A Mei, Y Stern, APD Mendes, ... Biological psychiatry 88 (2), 150-158, 2020 | 34 | 2020 |
Involvement of potassium and cation channels in hippocampal abnormalities of embryonic Ts65Dn and Tc1 trisomic mice S Stern, M Segal, E Moses EBioMedicine 2 (9), 1048-1062, 2015 | 31 | 2015 |
Chronaxie measurements in patterned neuronal cultures from rat hippocampus S Stern, A Agudelo-Toro, A Rotem, E Moses, A Neef PloS one 10 (7), e0132577, 2015 | 27 | 2015 |
Mood stabilizers in psychiatric disorders and mechanisms learnt from in vitro model systems R Nayak, I Rosh, I Kustanovich, S Stern International journal of molecular sciences 22 (17), 9315, 2021 | 25 | 2021 |
Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations Y Hussein, U Tripathi, A Choudhary, R Nayak, D Peles, I Rosh, T Rabinski, ... Translational Psychiatry 13 (1), 246, 2023 | 24 | 2023 |