Suivre
Ahmed R. Ali
Ahmed R. Ali
Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University
Adresse e-mail validée de mans.edu.eg
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Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo [2, 1-b] thiazole derivatives bearing pyrazole moieties
AR Ali, ER El-Bendary, MA Ghaly, IA Shehata
European journal of medicinal chemistry 75, 492-500, 2014
1142014
Novel acetamidothiazole derivatives: synthesis and in vitro anticancer evaluation
AR Ali, ER El-Bendary, MA Ghaly, IA Shehata
European Journal of Medicinal Chemistry 69, 908-919, 2013
352013
Anti-diabetic activities of phenolic compounds of Alternaria sp., an endophyte isolated from the leaves of desert plants growing in Egypt
A Elbermawi, AR Ali, Y Amen, A Ashour, KF Ahmad, ESS Mansour, ...
RSC advances 12 (38), 24935-24945, 2022
162022
Optimization of 1, 4-bis (arylsulfonamido) naphthalene-N, N'-diacetic acids as inhibitors of Keap1-Nrf2 protein-protein interaction to suppress neuroinflammation
DA Abed, S Lee, X Wen, AR Ali, V Mangipudy, LM Aleksunes, L Hu
Bioorganic & medicinal chemistry 44, 116300, 2021
132021
Combination of ligand and structure based virtual screening approaches for the discovery of potential PARP1 inhibitors
MM Al-Sanea, G Chilingaryan, N Abelyan, M Mamikonyan, H Gasparyan, ...
PLoS One 17 (9), e0272065, 2022
122022
Inhibitors of Keap1-Nrf2 protein-protein interaction reduce estrogen responsive gene expression and oxidative stress in estrogen receptor-positive breast cancer
T Xie, H Zahid, AR Ali, R Joyce, G Yang, C Winz, Y Le, R Zhou, ...
Toxicology and applied pharmacology 460, 116375, 2023
72023
6-(2-Morpholinoethyl)-thiazolo [3, 2-a] pyrimidin-5-one: A novel scaffold for the synthesis of potential PI3kα inhibitors
AR Ali, ER El-Bendary, MA Ghaly, IA Shehata
Egyptian journal of basic and applied sciences 5 (2), 183-189, 2018
62018
S-Alkylated quinazolin-4 (3H)-ones as dual EGFR/VEGFR-2 kinases inhibitors: design, synthesis, anticancer evaluation and docking study
SS Tawfik, A Hamdi, AR Ali, AA Elgazar, HW El-Shafey, AS El-Azab, ...
RSC advances 14 (36), 26325-26339, 2024
52024
Optimization of the C2 substituents on the 1,4-bis(arylsulfonamido)naphthalene-N,N′-diacetic acid scaffold for better inhibition of Keap1-Nrf2 protein-protein interaction
DA Abed, AR Ali, S Lee, MU Nguyen, MP Verzi, L Hu
European journal of medicinal chemistry 252, 115302, 2023
52023
Harnessing potential COX-2 engagement for boosting anticancer activity of substituted 2-mercapto-4 (3H)-quinazolinones with promising EGFR/VEGFR-2 inhibitory activities
A Hamdi, SS Tawfik, AR Ali, WA Ewes, A Haikal, AS El-Azab, AH Bakheit, ...
Bioorganic Chemistry 153, 107951, 2024
22024
Design, synthesis, and antitumor screening of new thiazole, thiazolopyrimidine, and thiazolotriazine derivatives as potent inhibitors of VEGFR‐2
AA Abd Elhameed, AR Ali, HA Ghabbour, SM Bayomi, NS El‐Gohary
Drug Development Research, 2023
22023
Metformin: a small molecule with multi-targets and diverse therapeutic applications
FA Badria, AR Ali, A Elbermawi, Y Amen, AF Badria
Metformin-A Prospective Alternative for the Treatment of Chronic Diseases, 2022
22022
Structural modification of C2-substituents on 1, 4-bis (arylsulfonamido) benzene or naphthalene-N, N′-diacetic acid derivatives as potent inhibitors of the Keap1-Nrf2 protein …
S Lee, AR Ali, DA Abed, MU Nguyen, MP Verzi, L Hu
European journal of medicinal chemistry 265, 116104, 2024
12024
One‐Pot Synthesis of 2‐Substituted Indoles and 7‐Azaindoles via Sequential Alkynylation and Cyclization of 2‐Iodo‐N‐mesylarylamines and Alkynes in the Presence of Cu2O
AR Ali, L Hu
Asian journal of organic chemistry, e202400421, 2025
2025
Multi-target directed ligands inspired natural products as an effective approach for the treatment of complex chronic health disorders
AE Shaaban, AR Ali, SN Ayyad, FA Badria
Bioorganic Chemistry, 108075, 2025
2025
Probing structural requirements for thiazole-based mimetics of sunitinib as potent VEGFR-2 inhibitors
AA Abd Elhameed, AR Ali, HA Ghabbour, SM Bayomi, NS El-Gohary
RSC Medicinal Chemistry, 2025
2025
A mini-review on integrase inhibitors: The cornerstone of next-generation HIV treatment
F Shalbi, AR Ali
European Journal of Medicinal Chemistry 279, 116900, 2024
2024
Self-supply of hydrogen peroxide by a bimetal-based nanocatalytic platform to enhance chemodynamic therapy for tumor treatment
T Yan, J Su, T Yan, J Bian, AR Ali, W Yuan, L Wei, Y Wang, M Gao, ...
Nanotechnology 36 (4), 045101, 2024
2024
Exploring the antiviral activity of secondary metabolites from Eriocephalus africanus var. africanus: In vitro and mechanistic in silico study
A Haikal, AA Galala, AR Ali, ME Elnosary, Y Amen, AA Gohar
South African Journal of Botany 174, 318-335, 2024
2024
Chemical composition and toxicity studies on Lantana camara L. flower essential oil and its in silico binding and pharmacokinetics to superoxide dismutase 1 for amyotrophic …
A Haikal, AR Ali
RSC advances 14 (33), 24250-24264, 2024
2024
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