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Lewis Amanda
Lewis Amanda
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Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, TE Moors, PP Navarro, ...
Nature neuroscience 22 (7), 1099-1109, 2019
8952019
Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles
S Hennig, G Kong, T Mannen, A Sadowska, S Kobelke, A Blythe, GJ Knott, ...
Journal of Cell Biology 210 (4), 529-539, 2015
3432015
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
F Laferrière, Z Maniecka, M Pérez-Berlanga, M Hruska-Plochan, ...
Nature neuroscience 22 (1), 65-77, 2019
1702019
The ins and outs of lncRNA structure: How, why and what comes next?
AJ Blythe, AH Fox, CS Bond
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (1), 46-58, 2016
1062016
Determinants of affinity and specificity in RNA-binding proteins
S Helder, AJ Blythe, CS Bond, JP Mackay
Current opinion in structural biology 38, 83-91, 2016
782016
The design and structural characterization of a synthetic pentatricopeptide repeat protein
BS Gully, KR Shah, M Lee, K Shearston, NM Smith, A Sadowska, ...
Acta Crystallographica Section D: Biological Crystallography 71 (2), 196-208, 2015
572015
Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer
H Robinson, JE Ruelcke, A Lewis, CS Bond, AH Fox, V Bharti, S Wani, ...
Clinical and translational medicine 11 (4), e381, 2021
382021
Lewy pathology in Parkinson’s disease consists of a crowded organellar, membranous medley
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, T Moors, PP Navarro, ...
biorxiv, 137976, 2017
342017
Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles
PP Navarro, C Genoud, D Castaño-Díez, A Graff-Meyer, AJ Lewis, ...
Scientific reports 8 (1), 18046, 2018
322018
Imaging of post-mortem human brain tissue using electron and X-ray microscopy
AJ Lewis, C Genoud, M Pont, WDJ Van de Berg, S Frank, H Stahlberg, ...
Current opinion in structural biology 58, 138-148, 2019
272019
The yeast transcription elongation factor Spt4/5 is a sequence‐specific RNA binding protein
AJ Blythe, B Yazar‐Klosinski, MW Webster, E Chen, M Vandevenne, ...
Protein Science 25 (9), 1710-1721, 2016
252016
Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA
D Ho, JA Kretzmann, M Norret, P Toshniwal, JP Veder, H Jiang, ...
Nature nanotechnology 13 (12), 1148-1153, 2018
222018
FTLD‐TDP assemblies seed neoaggregates with subtype‐specific features via a prion‐like cascade
P De Rossi, AJ Lewis, J Furrer, L De Vos, T Demeter, A Zbinden, W Zhong, ...
EMBO reports 22 (12), e53877, 2021
182021
The first transcriptomes from field-collected individual whiteflies (Bemisia tabaci, Hemiptera: Aleyrodidae): a case study of the endosymbiont composition
P Sseruwagi, J Wainaina, J Ndunguru, R Tumuhimbise, F Tairo, JY Guo, ...
Gates Open Research 1, 16, 2018
182018
Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions
I Lam, A Ndayisaba, AJ Lewis, YH Fu, GT Sagredo, A Kuzkina, ...
Neuron 112 (17), 2886-2909. e16, 2024
132024
Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy
C Böing, M Di Fabrizio, D Burger, JGJM Bol, E Huisman, AJM Rozemuller, ...
Brain, awae137, 2024
92024
Alterations in sub-axonal architecture between normal aging and Parkinson’s diseased human brains using label-free cryogenic X-ray nanotomography
HT Tran, EHR Tsai, AJ Lewis, T Moors, J Bol, I Rostami, A Diaz, AJ Jonker, ...
Frontiers in neuroscience 14, 570019, 2020
82020
Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5
A Blythe, S Gunasekara, J Walshe, JP Mackay, GA Hartzog, A Vrielink
Protein Expression and Purification 100, 54-60, 2014
52014
Ultrastructural diversity of alpha-Synuclein pathology in the post-mortem brain of Parkinson patients: implications for Lewy Body formation
A Lewis, L van den Heuvel, M Di Fabrizio, D Burger, E Huisman, ...
bioRxiv, 2024.07. 25.605088, 2024
12024
Structural Characteristics and Properties of the RNA-Binding Protein hnRNPK at Multiple Physical States
QD Le, A Lewis, A Dix-Matthews, P Ringler, A Duff, AE Whitten, R Atkin, ...
International Journal of Molecular Sciences 26 (3), 1356, 2025
2025
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