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Peter J. Carman
Peter J. Carman
Adresse e-mail validée de pennmedicine.upenn.edu
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BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton
PJ Carman, R Dominguez
Biophysical reviews 10 (6), 1587-1604, 2018
1462018
Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway
SE Cason, PJ Carman, C Van Duyne, J Goldsmith, R Dominguez, ...
Journal of Cell Biology 220 (7), e202010179, 2021
932021
Mining disaggregase sequence space to safely counter TDP-43, FUS, and α-synuclein proteotoxicity
A Tariq, JB Lin, ME Jackrel, CD Hesketh, PJ Carman, KL Mack, ...
Cell reports 28 (8), 2080-2095. e6, 2019
472019
Structures of the free and capped ends of the actin filament
PJ Carman, KR Barrie, G Rebowski, R Dominguez
Science 380 (6651), 1287-1292, 2023
372023
Structural insights into assembly and function of the RSC chromatin remodeling complex
RW Baker, JM Reimer, PJ Carman, B Turegun, T Arakawa, R Dominguez, ...
Nature Structural & Molecular Biology 28 (1), 71-80, 2021
372021
Tropomodulins control the balance between protrusive and contractile structures by stabilizing actin-tropomyosin filaments
R Kumari, Y Jiu, PJ Carman, S Tojkander, K Kogan, M Varjosalo, ...
Current Biology 30 (5), 767-778. e5, 2020
332020
Novel human cell expression method reveals the role and prevalence of posttranslational modification in nonmuscle tropomyosins
PJ Carman, KR Barrie, R Dominguez
Journal of Biological Chemistry 297 (4), 2021
172021
A solution to the long-standing problem of actin expression and purification
RH Ceron, PJ Carman, G Rebowski, M Boczkowska, RO Heuckeroth, ...
Proceedings of the National Academy of Sciences 119 (41), e2209150119, 2022
152022
Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins
FE Fregoso, M Boczkowska, G Rebowski, PJ Carman, T van Eeuwen, ...
Nature Communications 14 (1), 6894, 2023
82023
BAR domain proteins—a linkage between cellular membranes, signaling pathways, and the actin cytoskeleton. Biophys Rev 10: 1587–1604
PJ Carman, R Dominguez
72018
Transition state of Arp2/3 complex activation by actin-bound dimeric nucleation-promoting factor
T van Eeuwen, M Boczkowska, G Rebowski, PJ Carman, FE Fregoso, ...
Proceedings of the National Academy of Sciences 120 (33), e2306165120, 2023
62023
The LexA–RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation
MB Cory, A Li, CM Hurley, PJ Carman, RA Pumroy, ZM Hostetler, ...
Nature Structural & Molecular Biology, 1-10, 2024
52024
Novel protein production method combining native expression in human cells with an intein-based affinity purification and self-cleavable tag
PJ Carman, R Dominguez
Bio-protocol 12 (6), e4363-e4363, 2022
42022
Conformation of actin subunits at the barbed and pointed ends of F‐actin with and without capping proteins
KR Barrie, PJ Carman, R Dominguez
Cytoskeleton 80 (9-10), 309-312, 2023
32023
Drosophila Tropomodulin is required for multiple actin-dependent processes within developing myofibers
C Zapater, PJ Carman, DB Soffar, SE Windner, R Dominguez, MK Baylies
Development 150 (6), dev201194, 2023
32023
The LexA-RecA* structure reveals a lock-and-key mechanism for SOS activation
MB Cory, A Li, CM Hurley, PJ Carman, RA Pumroy, ZM Hostetler, ...
bioRxiv, 2023.10. 30.564768, 2023
22023
Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core
PJ Carman, G Rebowski, R Dominguez, SS Alqassim
Journal of structural biology 215 (2), 107960, 2023
22023
Molecular mechanisms linking missense ACTG2 mutations to visceral myopathy
RH Ceron, FA Báez-Cruz, NJ Palmer, PJ Carman, M Boczkowska, ...
Science Advances 10 (22), eadn6615, 2024
12024
High resolution structures of Myosin-IC reveal a unique actin-binding orientation, ADP release pathway, and power stroke trajectory
SS Chavali, PJ Carman, H Shuman, EM Ostap, CV Sindelar
bioRxiv, 2025.01. 10.632429, 2025
2025
Design principles to tailor Hsp104 therapeutics
JB Lin, PJ Carman, CW Gambogi, NM Kendsersky, E Chuang, SN Gates, ...
bioRxiv, 2024
2024
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