Therapeutic potential of spirooxindoles as antiviral agents N Ye, H Chen, EA Wold, PY Shi, J Zhou ACS infectious diseases 2 (6), 382-392, 2016 | 409 | 2016 |
Small molecule inhibitors targeting activator protein 1 (AP-1) miniperspective N Ye, Y Ding, C Wild, Q Shen, J Zhou Journal of medicinal chemistry 57 (16), 6930-6948, 2014 | 284 | 2014 |
Direct activation of Bax protein for cancer therapy Z Liu, Y Ding, N Ye, C Wild, H Chen, J Zhou Medicinal research reviews 36 (2), 313-341, 2016 | 249 | 2016 |
Discovery and development of natural product oridonin-inspired anticancer agents Y Ding, C Ding, N Ye, Z Liu, EA Wold, H Chen, C Wild, Q Shen, J Zhou European journal of medicinal chemistry 122, 102-117, 2016 | 179 | 2016 |
Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 “therapeutic window” Y Zhu, H Chen, S Boulton, F Mei, N Ye, G Melacini, J Zhou, X Cheng Scientific reports 5 (1), 9344, 2015 | 124 | 2015 |
Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel … N Ye, CH Chen, TT Chen, Z Song, JX He, XJ Huan, SS Song, Q Liu, ... Journal of medicinal chemistry 56 (7), 2885-2903, 2013 | 91 | 2013 |
Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders N Ye, JL Neumeyer, RJ Baldessarini, X Zhen, A Zhang Chem. Rev 113 (5), 274-302, 2013 | 85 | 2013 |
Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis C Ding, Y Zhang, H Chen, Z Yang, C Wild, N Ye, CD Ester, A Xiong, ... Journal of medicinal chemistry 56 (21), 8814-8825, 2013 | 83 | 2013 |
Recent advances in dopaminergic strategies for the treatment of Parkinson’s disease Q Mao, W Qin, A Zhang, N Ye Acta Pharmacologica Sinica 41 (4), 471-482, 2020 | 70 | 2020 |
Small molecules selectively targeting sigma-1 receptor for the treatment of neurological diseases N Ye, W Qin, S Tian, Q Xu, EA Wold, J Zhou, XC Zhen Journal of medicinal chemistry 63 (24), 15187-15217, 2020 | 68 | 2020 |
A review: conventional and supercritical hydro/solvothermal synthesis of ultrafine particles as cathode in lithium battery N Ye, T Yan, Z Jiang, W Wu, T Fang Ceramics International 44 (5), 4521-4537, 2018 | 66 | 2018 |
BH4 domain of Bcl-2 as a novel target for cancer therapy Z Liu, C Wild, Y Ding, N Ye, H Chen, EA Wold, J Zhou Drug discovery today 21 (6), 989-996, 2016 | 66 | 2016 |
Poly (ADP-ribose) polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials B Yuan, N Ye, SS Song, YT Wang, Z Song, HD Chen, CH Chen, XJ Huan, ... Cancer Letters 386, 47-56, 2017 | 60 | 2017 |
Discovery of potent anticancer agent HJC0416, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3) H Chen, Z Yang, C Ding, A Xiong, C Wild, L Wang, N Ye, G Cai, ... European journal of medicinal chemistry 82, 195-203, 2014 | 57 | 2014 |
Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets P Wang, Z Liu, H Chen, N Ye, X Cheng, J Zhou Bioorganic & medicinal chemistry letters 27 (8), 1633-1639, 2017 | 55 | 2017 |
Suppression of the growth and invasion of human head and neck squamous cell carcinomas via regulating STAT3 signaling and the miR-21/β-catenin axis with HJC0152 Y Wang, S Wang, Y Wu, Y Ren, Z Li, X Yao, C Zhang, N Ye, C Jing, ... Molecular cancer therapeutics 16 (4), 578-590, 2017 | 55 | 2017 |
Recent Advances in the Discovery of Small Molecules Targeting Exchange Proteins Directly Activated by cAMP (EPAC) Miniperspective H Chen, C Wild, X Zhou, N Ye, X Cheng, J Zhou Journal of medicinal chemistry 57 (9), 3651-3665, 2014 | 54 | 2014 |
Identification of N-propylnoraporphin-11-yl 5-(1, 2-dithiolan-3-yl) pentanoate as a new anti-Parkinson's agent possessing a dopamine D2 and serotonin 5-HT1A dual-agonist profile H Zhang, N Ye, S Zhou, L Guo, L Zheng, Z Liu, B Gao, X Zhen, A Zhang Journal of medicinal chemistry 54 (13), 4324-4338, 2011 | 54 | 2011 |
ent-Kaurane-based regio-and stereoselective inverse electron demand hetero-Diels–Alder reactions: synthesis of dihydropyran-fused diterpenoids C Ding, L Wang, H Chen, C Wild, N Ye, Y Ding, T Wang, MA White, ... Organic & biomolecular chemistry 12 (42), 8442-8452, 2014 | 49 | 2014 |
Structure–Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N′-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange … N Ye, Y Zhu, H Chen, Z Liu, FC Mei, C Wild, H Chen, X Cheng, J Zhou Journal of medicinal chemistry 58 (15), 6033-6047, 2015 | 48 | 2015 |