Genome engineering empowers the diatom Phaeodactylum tricornutum for biotechnology F Daboussi, S Leduc, A Maréchal, G Dubois, V Guyot, C Perez-Michaut, ... Nature communications 5 (1), 3831, 2014 | 473 | 2014 |
Overcoming transcription activator-like effector (TALE) DNA binding domain sensitivity to cytosine methylation J Valton, A Dupuy, F Daboussi, S Thomas, A Maréchal, R Macmaster, ... Journal of Biological Chemistry 287 (46), 38427-38432, 2012 | 303 | 2012 |
Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease S Grizot, J Smith, F Daboussi, J Prieto, P Redondo, N Merino, M Villate, ... Nucleic acids research 37 (16), 5405-5419, 2009 | 212 | 2009 |
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases P Redondo, J Prieto, IG Munoz, A Alibés, F Stricher, L Serrano, ... Nature 456 (7218), 107-111, 2008 | 191 | 2008 |
One-step generation of multiple gene knock-outs in the diatom Phaeodactylum tricornutum by DNA-free genome editing M Serif, G Dubois, AL Finoux, MA Teste, D Jallet, F Daboussi Nature Communications 9 (1), 3924, 2018 | 152 | 2018 |
DNA double-strand break repair signalling: the case of RAD51 post-translational regulation F Daboussi, A Dumay, F Delacôte, BS Lopez Cellular signalling 14 (12), 969-975, 2002 | 140 | 2002 |
Comprehensive analysis of the specificity of transcription activator-like effector nucleases A Juillerat, G Dubois, J Valton, S Thomas, S Stella, A Maréchal, ... Nucleic acids research 42 (8), 5390-5402, 2014 | 129 | 2014 |
Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases F Daboussi, M Zaslavskiy, L Poirot, M Loperfido, A Gouble, V Guyot, ... Nucleic acids research 40 (13), 6367-6379, 2012 | 111 | 2012 |
Genetic and metabolic engineering in diatoms W Huang, F Daboussi Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 104 | 2017 |
ATR/Chk1 pathway is essential for resumption of DNA synthesis and cell survival in UV-irradiated XP variant cells E Despras, F Daboussi, O Hyrien, K Marheineke, PL Kannouche Human molecular genetics 19 (9), 1690-1701, 2010 | 93 | 2010 |
Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™ A Dupuy, J Valton, S Leduc, J Armier, R Galetto, A Gouble, C Lebuhotel, ... PloS one 8 (11), e78678, 2013 | 92 | 2013 |
A homologous recombination defect affects replication-fork progression in mammalian cells F Daboussi, S Courbet, S Benhamou, P Kannouche, MZ Zdzienicka, ... Journal of cell science 121 (2), 162-166, 2008 | 88 | 2008 |
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus IG Munoz, J Prieto, S Subramanian, J Coloma, P Redondo, M Villate, ... Nucleic acids research 39 (2), 729-743, 2011 | 80 | 2011 |
Production of Medium Chain Fatty Acids by Yarrowia lipolytica: Combining Molecular Design and TALEN to Engineer the Fatty Acid Synthase C Rigouin, M Gueroult, C Croux, G Dubois, V Borsenberger, S Barbe, ... ACS synthetic biology 6 (10), 1870-1879, 2017 | 78 | 2017 |
Genome editing in diatoms: achievements and goals PG Kroth, AM Bones, F Daboussi, MI Ferrante, M Jaubert, M Kolot, ... Plant cell reports 37, 1401-1408, 2018 | 74 | 2018 |
APE1 overexpression in XRCC1-deficient cells complements the defective repair of oxidative single strand breaks but increases genomic instability M Sossou, C Flohr-Beckhaus, I Schulz, F Daboussi, B Epe, JP Radicella Nucleic acids research 33 (1), 298-306, 2005 | 57 | 2005 |
Optimized tuning of TALEN specificity using non-conventional RVDs A Juillerat, C Pessereau, G Dubois, V Guyot, A Maréchal, J Valton, ... Scientific reports 5 (1), 8150, 2015 | 53 | 2015 |
Engineering Meganuclease for Precise Plant Genome Modification F Daboussi, TJ Stoddard, F Zhang Advances in New Technology for Targeted Modification of Plant Genomes, 21-38, 2015 | 51 | 2015 |
Mitotic recombination between homologous chromosomes drives genomic diversity in diatoms P Bulankova, M Sekulić, D Jallet, C Nef, C Van Oosterhout, TO Delmont, ... Current Biology 31 (15), 3221-3232. e9, 2021 | 50 | 2021 |
BurrH: a new modular DNA binding protein for genome engineering A Juillerat, C Bertonati, G Dubois, V Guyot, S Thomas, J Valton, ... Scientific Reports 4 (1), 3831, 2014 | 48 | 2014 |