| Synthesis, anti-Toxoplasma gondii and antimicrobial activities of benzaldehyde 4-phenyl-3-thiosemicarbazones and 2-[(phenylmethylene) hydrazono]-4-oxo-3-phenyl-5 … TM de Aquino, AP Liesen, REA da Silva, VT Lima, CS Carvalho, ... Bioorganic & medicinal chemistry 16 (1), 446-456, 2008 | 164 | 2008 |
| Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1, 3, 4-thiadiazoles AP Liesen, TM de Aquino, CS Carvalho, VT Lima, JM de Araújo, ... European Journal of Medicinal Chemistry 45 (9), 3685-3691, 2010 | 157 | 2010 |
| Tiossemicarbazonas: métodos de obtenção, aplicações sintéticas e importância biológica RP Tenório, AJS Góes, JG Lima, AR Faria, AJ Alves, TM Aquino Química Nova 28, 1030-1037, 2005 | 117 | 2005 |
| 2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro KA da Franca Rodrigues, CN de Sousa Dias, PL do Nascimento Néris, ... European journal of medicinal chemistry 106, 1-14, 2015 | 79 | 2015 |
| Synthesis, Structure-Activity Relationships (SAR) and in Silico Studies of Coumarin Derivatives with Antifungal Activity RSA De Araújo, FQS Guerra, E de O. Lima, CA De Simone, JF Tavares, ... International journal of molecular sciences 14 (1), 1293-1309, 2013 | 68 | 2013 |
| Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi EF Silva-Júnior, EPS Silva, PHB França, JPN Silva, EO Barreto, EB Silva, ... Bioorganic & medicinal chemistry 24 (18), 4228-4240, 2016 | 64 | 2016 |
| The new era of drug discovery: The power of computer-aided drug design (CADD) IJS Nascimento, TM de Aquino, EF da Silva-Júnior Letters in Drug Design & Discovery 19 (11), 951-955, 2022 | 60 | 2022 |
| Antileishmanial activity of new thiophene–indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies MB Félix, ER de Souza, MCA de Lima, DKG Frade, VL Serafim, ... Bioorganic & Medicinal Chemistry 24 (18), 3972-3977, 2016 | 58 | 2016 |
| Active essential oils and their components in use against neglected diseases and arboviruses EC Luna, IS Luna, L Scotti, AFM Monteiro, MT Scotti, RO de Moura, ... Oxidative medicine and cellular longevity 2019 (1), 6587150, 2019 | 54 | 2019 |
| The medicinal chemistry of Chikungunya virus EF da Silva-Júnior, GO Leoncini, ÉES Rodrigues, TM Aquino, ... Bioorganic & Medicinal Chemistry 25 (16), 4219-4244, 2017 | 54 | 2017 |
| An electrochemical biosensor based on Hairpin-DNA modified gold electrode for detection of DNA damage by a hybrid cancer drug intercalation KL Untiveros, EG da Silva, FC de Abreu, EF da Silva-Júnior, ... Biosensors and Bioelectronics 133, 160-168, 2019 | 49 | 2019 |
| Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity S Das, CJ da Silva, MM Silva, MDA Dantas, Â de Fátima, ALTG Ruiz, ... Journal of advanced research 9, 51-61, 2018 | 47 | 2018 |
| Drug repurposing: A strategy for discovering inhibitors against emerging viral infections IJ dos Santos Nascimento, TM de Aquino, EF da Silva-Júnior Current Medicinal Chemistry 28 (15), 2887-2942, 2021 | 46 | 2021 |
| Preliminary antifungal and cytotoxic evaluation of synthetic cycloalkyl [b] thiophene derivatives with PLS-DA analysis BCC Souza, TB De Oliveira, TM Aquino, MCA de Lima, IR Pitta, ... Acta Pharmaceutica 62 (2), 221-236, 2012 | 46 | 2012 |
| Molecular modeling and physicochemical properties of supramolecular complexes of limonene with α-and β-cyclodextrins P dos Passos Menezes, PBP Dos Santos, GAA Dória, BMH de Sousa, ... AAPS PharmSciTech 18, 49-57, 2017 | 45 | 2017 |
| An update on Staphylococcus aureus NorA efflux pump inhibitors KLC Monteiro, TM de Aquino, FJB Mendonça Junior Current topics in medicinal chemistry 20 (24), 2168-2185, 2020 | 44 | 2020 |
| Molecular docking studies applied to a dataset of cruzain inhibitors EF da Silva-Junior, PH Barcellos Franca, FF Ribeiro, ... Current Computer-Aided Drug Design 14 (1), 68-78, 2018 | 41 | 2018 |
| Cruzain and rhodesain inhibitors: last decade of advances in seeking for new compounds against American and African trypanosomiases IJ dos Santos Nascimento, TM de Aquino, EF da Silva-Júnior Current topics in medicinal chemistry 21 (21), 1871-1899, 2021 | 40 | 2021 |
| Improvement of solubility and antifungal activity of a new aminothiophene derivative by complexation with 2-hydroxypropyl-β-cyclodextrin GRA Eleamen, SC Costa, RG Lima-Neto, RP Neves, LA Rolim, ... Journal of the Brazilian Chemical Society 28, 116-125, 2017 | 40 | 2017 |
| Kinetic and physical-chemical study of the inclusion complex of β-cyclodextrin containing carvacrol P dos Passos Menezes, MR Serafini, YMBG de Carvalho, DVS Santana, ... Journal of Molecular Structure 1125, 323-330, 2016 | 40 | 2016 |
Edeildo Ferreira da Silva JuniorLaboratório de Química Medicinal, Universidade Federal de AlagoasAdresse e-mail validée de iqb.ufal.br