| Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells AE Boitano, J Wang, R Romeo, LC Bouchez, AE Parker, SE Sutton, ... Science 329 (5997), 1345-1348, 2010 | 1289 | 2010 |
| Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling BC DiNatale, IA Murray, JC Schroeder, CA Flaveny, TS Lahoti, ... Toxicological sciences 115 (1), 89-97, 2010 | 694 | 2010 |
| The uremic toxin 3-indoxyl sulfate is a potent endogenous agonist for the human aryl hydrocarbon receptor JC Schroeder, BC DiNatale, IA Murray, CA Flaveny, Q Liu, ... Biochemistry 49 (2), 393-400, 2010 | 339 | 2010 |
| Broad anti-tumor activity of a small molecule that selectively targets the Warburg effect and lipogenesis CA Flaveny, K Griffett, BEDM El-Gendy, M Kazantzis, M Sengupta, ... Cancer cell 28 (1), 42-56, 2015 | 209 | 2015 |
| Ligand selectivity and gene regulation by the human aryl hydrocarbon receptor in transgenic mice CA Flaveny, IA Murray, CR Chiaro, GH Perdew Molecular pharmacology 75 (6), 1412-1420, 2009 | 153 | 2009 |
| Fluorophore-NanoLuc BRET Reporters Enable Sensitive In Vivo Optical Imaging and Flow Cytometry for Monitoring Tumorigenesis FX Schaub, MS Reza, CA Flaveny, W Li, AM Musicant, S Hoxha, M Guo, ... Cancer research 75 (23), 5023-5033, 2015 | 137 | 2015 |
| Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity IA Murray, JL Morales, CA Flaveny, BC DiNatale, C Chiaro, K Gowdahalli, ... Molecular pharmacology 77 (2), 247-254, 2010 | 123 | 2010 |
| Differential gene regulation by the human and mouse aryl hydrocarbon receptor CA Flaveny, IA Murray, GH Perdew Toxicological Sciences 114 (2), 217-225, 2010 | 122 | 2010 |
| Ah receptor represses acute-phase response gene expression without binding to its cognate response element RD Patel, IA Murray, CA Flaveny, A Kusnadi, GH Perdew Laboratory investigation 89 (6), 695-707, 2009 | 121 | 2009 |
| The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis K Griffett, RD Welch, CA Flaveny, GR Kolar, BA Neuschwander-Tetri, ... Molecular metabolism 4 (4), 353-357, 2015 | 95 | 2015 |
| Transgenic humanized AHR mouse reveals differences between human and mouse AHR ligand selectivity CA Flaveny, GH Perdew Molecular and cellular pharmacology 1 (3), 119, 2009 | 92 | 2009 |
| Pyrvinium attenuates Hedgehog signaling downstream of smoothened B Li, DL Fei, CA Flaveny, N Dahmane, V Baubet, Z Wang, F Bai, XH Pei, ... Cancer research 74 (17), 4811-4821, 2014 | 88 | 2014 |
| Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties IA Murray, G Krishnegowda, BC DiNatale, C Flaveny, C Chiaro, JM Lin, ... Chemical research in toxicology 23 (5), 955-966, 2010 | 86 | 2010 |
| Antagonism of aryl hydrocarbon receptor signaling by 6, 2′, 4′-trimethoxyflavone IA Murray, CA Flaveny, BC DiNatale, CR Chairo, JC Schroeder, ... Journal of Pharmacology and Experimental Therapeutics 332 (1), 135-144, 2010 | 82 | 2010 |
| Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis B Li, CA Flaveny, C Giambelli, DL Fei, L Han, BI Hang, F Bai, XH Pei, ... PloS one 9 (7), e101969, 2014 | 73 | 2014 |
| Inhibition of the key metabolic pathways, glycolysis and lipogenesis, of oral cancer by bitter melon extract S Sur, H Nakanishi, C Flaveny, JE Ippolito, J McHowat, DA Ford, RB Ray Cell Communication and Signaling 17, 1-13, 2019 | 70 | 2019 |
| LXR-inverse agonism stimulates immune-mediated tumor destruction by enhancing CD8 T-cell activity in triple negative breast cancer KJ Carpenter, AC Valfort, N Steinauer, A Chatterjee, S Abuirqeba, ... Scientific reports 9 (1), 19530, 2019 | 62 | 2019 |
| The mouse and human Ah receptor differ in recognition of LXXLL motifs C Flaveny, RK Reen, A Kusnadi, GH Perdew Archives of biochemistry and biophysics 471 (2), 215-223, 2008 | 62 | 2008 |
| Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-α-naphthoflavone IA Murray, CA Flaveny, CR Chiaro, AK Sharma, RS Tanos, JC Schroeder, ... Molecular Pharmacology 79 (3), 508-519, 2011 | 61 | 2011 |
| Hedgehog signaling regulates bladder cancer growth and tumorigenicity DL Fei, A Sanchez-Mejias, Z Wang, C Flaveny, J Long, S Singh, ... Cancer research 72 (17), 4449-4458, 2012 | 60 | 2012 |