| What is flux balance analysis? JD Orth, I Thiele, BØ Palsson Nature biotechnology 28 (3), 245-248, 2010 | 4438 | 2010 |
| Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ... Nature biotechnology 34 (8), 828-837, 2016 | 3763 | 2016 |
| A protocol for generating a high-quality genome-scale metabolic reconstruction I Thiele, BØ Palsson Nature protocols 5 (1), 93-121, 2010 | 2079 | 2010 |
| A genome‐scale metabolic reconstruction for Escherichia coli K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information AM Feist, CS Henry, JL Reed, M Krummenacker, AR Joyce, PD Karp, ... Molecular systems biology 3 (1), 121, 2007 | 1770 | 2007 |
| Global reconstruction of the human metabolic network based on genomic and bibliomic data NC Duarte, SA Becker, N Jamshidi, I Thiele, ML Mo, TD Vo, R Srivas, ... Proceedings of the National Academy of Sciences 104 (6), 1777-1782, 2007 | 1696 | 2007 |
| Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2. 0 J Schellenberger, R Que, RMT Fleming, I Thiele, JD Orth, AM Feist, ... Nature protocols 6 (9), 1290-1307, 2011 | 1657 | 2011 |
| Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network J Förster, I Famili, P Fu, BØ Palsson, J Nielsen Genome research 13 (2), 244-253, 2003 | 1452 | 2003 |
| Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110 A Varma, BO Palsson Applied and environmental microbiology 60 (10), 3724-3731, 1994 | 1357 | 1994 |
| An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR) JL Reed, TD Vo, CH Schilling, BO Palsson Genome biology 4, 1-12, 2003 | 1334 | 2003 |
| A comprehensive genome‐scale reconstruction of Escherichia coli metabolism—2011 JD Orth, TM Conrad, J Na, JA Lerman, H Nam, AM Feist, BØ Palsson Molecular systems biology 7 (1), 535, 2011 | 1323 | 2011 |
| Genome-scale models of microbial cells: evaluating the consequences of constraints ND Price, JL Reed, BØ Palsson Nature Reviews Microbiology 2 (11), 886-897, 2004 | 1310 | 2004 |
| COBRApy: constraints-based reconstruction and analysis for python A Ebrahim, JA Lerman, BO Palsson, DR Hyduke BMC systems biology 7, 1-6, 2013 | 1308 | 2013 |
| The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities JS Edwards, BO Palsson Proceedings of the National Academy of Sciences 97 (10), 5528-5533, 2000 | 1288 | 2000 |
| In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data JS Edwards, RU Ibarra, BO Palsson Nature biotechnology 19 (2), 125-130, 2001 | 1282 | 2001 |
| A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013 | 1230 | 2013 |
| Metabolic flux balancing: basic concepts, scientific and practical use A Varma, BO Palsson Bio/technology 12 (10), 994-998, 1994 | 1218 | 1994 |
| Systems biology: properties of reconstructed networks BØ Palsson Cambridge university press, 2006 | 1184 | 2006 |
| Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0 L Heirendt, S Arreckx, T Pfau, SN Mendoza, A Richelle, A Heinken, ... Nature protocols 14 (3), 639-702, 2019 | 1180 | 2019 |
| Reconstruction of biochemical networks in microorganisms AM Feist, MJ Herrgård, I Thiele, JL Reed, BØ Palsson Nature Reviews Microbiology 7 (2), 129-143, 2009 | 1105 | 2009 |
| Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth RU Ibarra, JS Edwards, BO Palsson Nature 420 (6912), 186-189, 2002 | 1078 | 2002 |
