Combination approaches to combat multidrug-resistant bacteria RJ Worthington, C Melander Trends in biotechnology 31 (3), 177-184, 2013 | 734 | 2013 |
Inhibition of HIV fusion with multivalent gold nanoparticles MC Bowman, TE Ballard, CJ Ackerson, DL Feldheim, DM Margolis, ... Journal of the American Chemical Society 130 (22), 6896-6897, 2008 | 468 | 2008 |
Small molecule control of bacterial biofilms RJ Worthington, JJ Richards, C Melander Organic & biomolecular chemistry 10 (37), 7457-7474, 2012 | 367 | 2012 |
Overcoming resistance to β-lactam antibiotics RJ Worthington, C Melander The Journal of organic chemistry 78 (9), 4207-4213, 2013 | 296 | 2013 |
Synergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agents SA Rogers, RW Huigens III, J Cavanagh, C Melander Antimicrobial agents and chemotherapy 54 (5), 2112-2118, 2010 | 269 | 2010 |
Narrow-spectrum antibacterial agents RJ Melander, DV Zurawski, C Melander Medchemcomm 9 (1), 12-21, 2018 | 267 | 2018 |
Controlling bacterial biofilms JJ Richards, C Melander Chembiochem 10 (14), 2287-2294, 2009 | 260 | 2009 |
The challenge of overcoming antibiotic resistance: an adjuvant approach? RJ Melander, C Melander ACS infectious diseases 3 (8), 559-563, 2017 | 240 | 2017 |
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands RK Suto, RS Edayathumangalam, CL White, C Melander, JM Gottesfeld, ... Journal of molecular biology 326 (2), 371-380, 2003 | 209 | 2003 |
Inhibition of Pseudomonas aeruginosa Biofilm Formation with Bromoageliferin Analogues RW Huigens, JJ Richards, G Parise, TE Ballard, W Zeng, R Deora, ... Journal of the American Chemical Society 129 (22), 6966-6967, 2007 | 197 | 2007 |
Biologically inspired strategies for combating bacterial biofilms MS Blackledge, RJ Worthington, C Melander Current opinion in pharmacology 13 (5), 699-706, 2013 | 185 | 2013 |
Sequence specific fluorescence detection of double strand DNA VC Rucker, S Foister, C Melander, PB Dervan Journal of the American Chemical Society 125 (5), 1195-1202, 2003 | 185 | 2003 |
Synthesis and Screening of an Oroidin Library against Pseudomonas aeruginosa Biofilms JJ Richards, TE Ballard, RW Huigens III, C Melander ChemBioChem 9 (8), 1267-1279, 2008 | 180 | 2008 |
Construction and screening of a 2‐aminoimidazole library identifies a small molecule capable of inhibiting and dispersing bacterial biofilms across order, class, and phylum SA Rogers, C Melander Angewandte Chemie 120 (28), 5307-5309, 2008 | 175 | 2008 |
Anti-biofilm compounds derived from marine sponges SD Stowe, JJ Richards, AT Tucker, R Thompson, C Melander, ... Marine drugs 9 (10), 2010-2035, 2011 | 165 | 2011 |
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA· TTC repeats in Friedreich's ataxia R Burnett, C Melander, JW Puckett, LS Son, RD Wells, PB Dervan, ... Proceedings of the National Academy of Sciences 103 (31), 11497-11502, 2006 | 162 | 2006 |
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides JM Gottesfeld, C Melander, RK Suto, H Raviol, K Luger, PB Dervan Journal of Molecular Biology 309 (3), 615-629, 2001 | 160 | 2001 |
Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues JJ Richards, TE Ballard, C Melander Organic & biomolecular chemistry 6 (8), 1356-1363, 2008 | 146 | 2008 |
Controlling bacterial behavior with indole-containing natural products and derivatives RJ Melander, MJ Minvielle, C Melander Tetrahedron 70 (37), 6363-6372, 2014 | 142 | 2014 |
Library-based lead compound discovery: Antioxidants by an analogous synthesis/deconvolutive assay strategy MJ Kurth, LA Ahlberg Randall, C Chen, C Melander, RB Miller, ... The Journal of Organic Chemistry 59 (20), 5862-5864, 1994 | 138 | 1994 |